Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Displaying 41 results

Traits related to biotic stress tolerance

Fungal resistance: Increased tolerance against Fusarium oxysporum f. sp. lycopersici, causing vascular wilt.
(Ijaz et al., 2022)
SDN1
CRISPR/Cas
University of Agriculture, Pakistan
Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA
Viral resistance: to Cotton Leaf Curl Kokhran Virus, causing Cotton leaf curl disease (CLCuD), a very devastating and prevalent disease. CLCuD causes huge losses to the textile and other industries.
(Hamza et al., 2021)
SDN1
CRISPR/Cas
National Institute for Biotechnology and Genetic Engineering, Pakistan
Broad-spectrum resistance against multiple Potato virus Y (PVY)-strains.
( Noureen et al., 2022 )
SDN1
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences (PIEAS)
University Institute of Biochemistry and Biotechnology (UIBB), Pakistan
Viral resistance: resistance to rice tungro spherical virus, causing rice tungro disease (RTD). RTD is a serious threat for rice production in tropical Asia.
(Macovei et al., 2018)
SDN1
CRISPR/Cas
International Rice Research Institute (IRRI), Philippines
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Xu et al., 2021)
SDN1
TALENs
Shanghai Jiao Tong University, China
Crop Diseases Research Institute, Pakistan
Viral resistance: reduced cotton leaf curl viral (CLCuV) load with asymptomatic plants. <br /> CLCuV causes a very devastating and prevalent disease. It causes huge losses to textile and other industries.
(Shakoor et al., 2023)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Pacific Biosciences
CureVac Manufacturing GmbH, Germany
Broad-spectrum disease resistance without yield loss.
( Sha et al., 2023 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Chengdu Normal University
Jiangxi Academy of Agricultural Sciences
Anhui Agricultural University
BGI-Shenzhen
Northwest A&
F University
Shandong Academy of Agricultural Sciences, China
Université de Bordeaux, France
University of California
The Joint BioEnergy Institute, USA
University of Adelaide, Australia
Bacterial resistance: improved resistance to Xanthomonas oryzae, which causes bacterial blight, a devastating rice disease resulting in yield losses.
(Oliva et al., 2019)
SDN1
CRISPR/Cas
International Rice Research Institute, Philippines
University of Missouri
University of Florida
Iowa State University
Donald Danforth Plant Science Center, USA
Université Montpellier, France
Heinrich Heine Universität Düsseldorf
Max Planck Institute for Plant Breeding Research
Erfurt University of Applied Sciences, Germany
Nagoya University, Japan
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zafar et al., 2020)
SDN1
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences
University of Information Technology
Engineering and Management Sciences
Constituent College of Pakistan Institute of Engineering and Applied Sciences, Pakistan
Viral resistance: increased resistance to chickpea chlorotic dwarf virus (CpCDV).
(Malik et al., 2023)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Traits related to abiotic stress tolerance

Drought and salt tolerance.
( Curtin et al., 2018 )
SDN1
CRISPR/Cas
University of Minnesota, USA
The University of Newcastle, Australia

Traits related to improved food/feed quality

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )
SDN1
CRISPR/Cas
Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia
Improved cold storage and processing traits: lower levels of reduced sugars
(Yasmeen et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab, Pakistan
Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)
SDN1
CRISPR/Cas
Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia
Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )
SDN1
CRISPR/Cas
Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia
Specific differences in grain morphology, composition and (1,3;1,4)-β-glucan content. Barley rich in (1,3;1,4)-β-glucan, a source of fermentable dietary fibre, is useful to protect against various human health conditions. However, low grain (1,3;1,4)-β-glucan content is preferred for brewing and distilling.
( Garcia-Gimenez et al., 2020 )
SDN1
CRISPR/Cas
The James Hutton Institute
University of Dundee, UK
University of Adelaide
La Trobe University, Australia
Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

BE
Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia
Reduce malnutrition by decreasing antinutrient phytic acid (PA) and increasing Iron and Zinc accumulation. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)
SDN1
CRISPR/Cas
Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia
Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )
SDN1
CRISPR/Cas
Zhejiang University, China
La Trobe University, Australia
Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
Reduced browning and acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods and is regarded as a potential carcinogen and neurotoxin.
( Nguyen Phuoc Ly et al., 2023 )
SDN1
CRISPR/Cas
Murdoch University, Australia

Traits related to increased plant yield and growth

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )
SDN1
CRISPR/Cas
University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China
Increase in 1000-grain weight, grain area, grain width, grain length, plant height, and spikelets per spike.
( Errum et al., 2023 )
SDN1
CRISPR/Cas
National Agricultural Research Centre (NARC)
PARC Institute of Advanced Studies in Agriculture (PIASA)
Pakistan Agricultural Research Council, Pakistan
Reduced seed dormancy: rapid and uniform germination of seeds is important for rice production. Mutant seeds began to germinate 1 day after sowing, while WT seeds needed 2 days.
(Jung et al., 2019)
SDN1
CRISPR/Cas
Hankyong National University
Chungbuk National University
Hanyang University, China
Central Luzon State University, Philippines
Increase in plant height, tiller number, grain protein content and yield. 1.5- to 2.8-fold increase in total chlorophyll content in the flag leaf at the grain filling stage. Delayed senescence by 10–14 days. High nitrogen content in shoots under low nitrogen conditions.
( Karunarathne et al., 2022 )
SDN1
CRISPR/Cas
Murdoch University
Department of Primary Industries and Regional Development, Australia
Transformation of a climbing woody perennial, developing axillary inflorescences after many years of juvenility, into a compact plant with rapid terminal flower and fruit development.
( Varkonyi-Gasic et al., 2022 )
SDN1
CRISPR/Cas
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research), University of Auckland, New Zealand
Control grain size and seed coat color.
( Tra et al., 2021 )

BE
International Rice Research Institute, Philippines
Dahlem Center of Plant Sciences Freie Universität, Germany
Synthetic Biology, Biofuel and Genome Editing R&
D Reliance Industries Ltd, India
Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )
SDN1
CRISPR/Cas
Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, Korea
Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
Murdoch University, Australia
Improved spikelet number per panicle led to increased grain yield per plant.
( Ludwig et al., 2023 )
SDN1
CRISPR/Cas
International Rice Research Institute (IRRI), Philippines
University of Pavia, Italy
Increased grain yield without side effect.
( Gho et al., 2022 )
SDN1
CRISPR/Cas
Kyung Hee University, South Korea
International Rice Research Institute, Philippines

Traits related to industrial utilization

Early heading: in regions with short growing seasons, early maturing varieties to escape frost damage are required.
(Sohail et al., 2022)
SDN1
CRISPR/Cas
China National Rice Research Institute
Northern Center of China National Rice Research Institute
Zhejiang A&
F University, China
Mir Chakar Khan Rind University
Agriculture Research System Khyber, Pakistan
Ministry of Agriculture, Bangladesh
Agriculture Research Center, Egypt
Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )
SDN1
CRISPR/Cas
The University of Adelaide, Australia
Huaiyin Normal University, China

Traits related to herbicide tolerance

Herbicide tolerance (ALS-targeting)
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu Academy of Agricultural Sciences
Jiangsu University, China
CSIRO Agriculture and Food, Australia
Herbicide tolerance: Bispyribac-sodium (BS). BS is a pyrimidinyl carboxy herbicide.
(Zafar et al., 2023)
SDN2
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences
Engineering and Management Sciences (BUITEMS), Pakistan
Herbicide glyphosate tolerance.
( Arndell et al., 2019 )
SDN1
CRISPR/Cas
CSIRO
New South Wales Department of Primary Industries
The University of Adelaide, Australia
Imazethapyr, imazapic
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu University, China
CSIRO Agriculture and Food, Australia

Traits related to product color/flavour

Reduced citrate content. Citrate is a common primary metabolite which often characterizes fruit flavour.
( Fu et al., 2023 )
SDN1
CRISPR/Cas
Zhejiang University, China
University of Florida, USA
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research) Mt Albert
University of Auckland, New Zealand
Albinism and dwarfing.
( Naim et al., 2018 )
SDN1
CRISPR/Cas
Queensland University of Technology, Australia