Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Displaying 56 results

Traits related to biotic stress tolerance

Fungal resistance: Enhanced resistance to the pathogen Sclerotinia sclerotiorum.
(Sun et al., 2018)
SDN1
CRISPR/Cas
Yangzhou University, China
Fungal resistance: contribute to Sclerotinia sclerotiorum resistance.
(Zhang et al., 2022)
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Oilseed rape mutant with non-abscising floral organs. Clerotinia stem rot (SSR), caused by Sclerotinia sclerotiorum is a detrimental fungal disease for oilseed rape. Petal infection is crucial to the prevalence of SSR in oilseed rape. Oilseed rape varieties with abscission-defective floral organs were predicted to be less susceptible to Sclerotinia infection and to have a longer flowering period to enhance tourism income.
( Wu et al., 2022 )
SDN1
CRISPR/Cas
Yangzhou University, China
High resistance to powdery mildew under semi-commercial growth conditions.
( Shnaider et al., 2022 )
SDN1
CRISPR/Cas
Agricultural Research Organization Volcani Center, Israel
Fungal resistance: reduced susceptibility to Verticillium longisporum, a pathogen causing Verticillium stem striping. No fungicide treatments are currently available to control this disease.
(Pröbsting et al., 2020)
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
NPZ Innovation GmbH, Germany
Virus resistance: Immunity to cucumber vein yellowing virus infection (Ipomovirus) and resistance to the potyviruses Zucchini yellow mosaic virus and Papaya ring spot mosaic virus.
(Chandrasekaran et al., 2016)
SDN1
CRISPR/Cas
Volcani Center, Israel
Viral resistance: Increased resistance against watermelon mosaic virus (WMV), papaya ringspot virus (PRSV), and zucchini yellow mosaic virus (ZYMV).
(Fidan et al., 2023)
SDN1
CRISPR/Cas
Akdeniz University
Research and Development Department AD ROSSEN Seeds, Turkey
Visual detection of brassica yellows virus (BrYV), an economically important virus on cruciferous species. This assay allows for convenient, portable, rapid, low-cost, highly sensitive and specific detection and has great potential for on-site monitoring of BrYV.
( Xu et al., 2023 )
SDN1
CRISPR/Cas
Guizhou University, China
Fungal resistance: broad-spectrum stress tolerance including Pseudoperonospora cubernsis (P. cubensis) resistance. P. cubensis is the causal agent of cucurbit downy mildew, responsible for devastating losses worldwide of cucumber, cantaloupe, pumpkin, watermelon and squash.
(Dong et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California, USA
Resistance against a protist pathogen: stable resistance against clubroot disease. Clubroot disease is caused by the protist Plasmodiophora brassicae Woronin and can result in a 10-15% yield loss in Brassica species as well as related crops.
(Hu et al., 2023)
SDN1
CRISPR/Cas
Saskatoon Research and Development Centre, Canada
Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands

Traits related to abiotic stress tolerance

Enhanced drought tolerance
( Wu et al., 2020 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Reduction in cadmium accumulation. Cadmium is a heavy metal, harmful for human health.
( Yao et al., 2022 )
SDN1
CRISPR/Cas
Sichuan University
Science and Technology Innovation Center of Sichuan Modern Seed Industry Group, China
Improved drought tolerance.
( Linghu et al., 2023 )
SDN1
CRISPR/Cas
Hybrid Rapeseed Research Center of Shaanxi Province
Northwest A &
F University, China
Broad-spectrum stress tolerance: enhanced low temperature, salinity, Pseudoperonospora cubensis and water-deficit tolerance.
(Dong et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California, USA

Traits related to improved food/feed quality

Improved fatty acid content: increased content of oleic acid, reduced erucic acid levels and slightly decreased polyunsaturated fatty acids content. Fatty acid composition is important for human health and shelf life.
(Shi et al., 2022)
SDN1
CRISPR/Cas
Zhejiang Academy of Agricultural Sciences, China
Boosted cytokinin biosynthesis and elevated cucumber fruit wart formation. Warty fruit is an important quality trait that greatly affects market value and fruit appearance.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Modified fatty acid profile: increased oleic acid, decreased linoleic and linolenic acid content.
(Huang et al., 2020)
SDN1
CRISPR/Cas
National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, China
Yellow-seed production, a desirable trait with great potential for improving seed quality in Brassica crops. The formation of seed colour is due to the deposition of the oxidized form of a flavonoid, called proanthocyanidins (PA). Yellow seeds have a higher oil content.
( Zhai et al., 2019 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Regulate cucumber fruit wart formation. Warty fruit in cucumber is an important quality trait that greatly affects fruit appearance.
( Wang et al., 2021 )
SDN1
CRISPR/Cas
China Agricultural University, China
Fine-tuning sugar content. Consumer preference varies along regional, cultural, and age lines, thus the solution is to create a continuum of phenotypic “taste” changes
( Xing et al., 2020 )

BE
Chinese Academy of Sciences
China Agricultural University, China
Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Sashidhar et al., 2020 )
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel
Max-Planck-Institute for Evolutionary Biology, Germany
Altered lignin composition: decreased syringyl monolignol / guaiacylmonolignol (S/G) ratio. The monolignol ratio has been proposed to affect biomass recalcitrance and the resistance to plant disease.
(Cao et al., 2021)
SDN1
CRISPR/Cas
SouthwestUniversity, China
University of Wisconsin, USA
Increasing seed oil content (SOC).
( Zhang et al., 2022 )
SDN1
CRISPR/Cas
Huazhong University of Science and Technology, China
Improved fatty acid composition. The content and abundance of fatty acids play an important role in nutritional and processing applications of oilseeds.
( Okuzaki et al., 2018 )
SDN1
CRISPR/Cas
Tamagawa University
Osaka Prefecture University
Tamagawa University, Japan
Decreases in palmitic acid, increased total C18 and reduced total saturated fatty acid contents. Reduced saturated fat content is connected to lowered cardiovascular disease rate.
( Gupta et al., 2012 )
SDN1
ZFN
Dow AgroSciences
Sangamo BioSciences, USA
Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )
SDN1
CRISPR/Cas
Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia
Low erucic acid (EA) content. Composition of fatty acids affects the edible and processing quality of vegetable oils. EA is potentially to cause health problems.
( Liu et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
National Research Council Canada, Canada
Nattokinase (NK) producing cucumber. NK is effective in the prevention and treatment of cardiovascular disease.
( Ni et al., 2023 )
SDN2
CRISPR/Cas
Xuzhou University of Technology
Nankai University, China
Increased phosphorus and anthocyanin content.
( Zhang et al., 2023 )
SDN1
CRISPR/Cas
Shenyang Agricultural University
Ministry of Education, China
Increased phosphorus content and improved fruit quality.
( Zhang et al., 2023 )
SDN1
CRISPR/Cas
Shenyang Agricultural University
Ministry of Education, China

Traits related to increased plant yield and growth

Increased shatter resistance to avoid seed loss during mechanical harvest.
( Braatz et al., 2017 )
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel, Germany
Increased seeds number per husk, higher seed weight.
( Yang et al., 2018 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Confer shoot architectural changes for increased resource inputs to increase crop yield.
( Stanic et al., 2021 )
SDN1
CRISPR/Cas
University of Calgary, Canada
SRM Institute of Technology, India
Improve plant architecture to increase yield. Plant height and branch number are directly correlated with yield.
( Zheng et al., 2020 )
SDN1
CRISPR/Cas
Ministry of Agriculture, China
Wilkes University, USA
Semi-dwarf phenotype and compact architecture to increase yield. Plant height and branch angle are the major architectural factors determining yield.
( Fan et al., 2021 )
SDN1
CRISPR/Cas
Ministry of Agriculture and Rural Affairs, China
Wilkes University, USA
Only female flowers. Allows earlier production of hybrids, higher yield, and more concentrated fruit set.
( Hu et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences,
China
Faster seedling growth.
( Zhou et al., 2018 )
SDN1
CRISPR/Cas
University of Maryland, USA
Increased spine density. The “numerous spines (ns)” cucumber varieties are popular in Europe and West Asia.
( Liu et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Early-flowering varieties. The timing of flowering is an important event in the life cycle of flowering plants.
( Jiang et al., 2018 )
SDN1
CRISPR/Cas
Hunan Agricultural University, China
Université de Strasbourg, France
Increased seed oil content (SOC). SOC is a major determinant of yield and quality.
( Karunarathna et al., 2020 )
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel, Germany
Zhejiang University, China
Transformation of a climbing woody perennial, developing axillary inflorescences after many years of juvenility, into a compact plant with rapid terminal flower and fruit development.
( Varkonyi-Gasic et al., 2022 )
SDN1
CRISPR/Cas
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research), University of Auckland, New Zealand

Traits related to industrial utilization

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Manipulation of flowering time to develop cultivars with desired maturity dates. Stabilization of flowering time and period supports efficient mechanised harvesting.
( Ahmar et al., 2021 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Self-incompatibility to prevent inbreeding in hermaphrodite angiosperms via the rejection of self-pollen.
( Dou et al., 2021 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Generating genic male sterility lines (GMS). GMS can promote heterosis in rapeseed. Compared with other approaches, GMS brings about nearly complete male sterility to a hybrid breeding program.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
Northwest A&
F University
Hybrid Rapeseed Research Centre of Shaanxi Province, China
Reversible complete male sterility. Very precise hormone mediated control of male fertility transition showed great potential for hybrid seed production in Brassica species crops.
( Cheng et al., 2023 )
SDN1
CRISPR/Cas
Ministry of Agriculture and Rural Affairs
Henan Normal University, China

Traits related to herbicide tolerance

Herbicide tolerance: AHAS-inhibiting
(Gocal et al., 2015)

ODM
Cibus, Canada
Cibus, USA
Glyphosate
( Wang et al., 2021 )

CRISPR/Cas
Huazhong Agricultural University
Anhui Academy of Agricultural Sciences, China
Tribenuron methyl
( Wu et al., 2020 )

BE
Yangzhou University
Shanghai Normal University, China

Traits related to product color/flavour

Albino phenotype.
( Wilson et al., 2019 )
SDN1
CRISPR/Cas
NIAB EMR, UK
Altered color of petals and leaves.
( Li et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Hubei Hongshan Laboratory, China
Albino phenotype.
( Wang et al., 2018 )
SDN1
CRISPR/Cas
Provincial Key Laboratory of Applied Botany
Guangdong Provincial Key Laboratory of Applied Botany
University of Chinese Academy of Sciences, China
Yellow colored seed.
( Huang et al., 2023 )
SDN1
CRISPR/Cas
Hunan Academy of Agricultural Sciences
Hunan University of Science and Technology
Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, China
Reduced citrate content. Citrate is a common primary metabolite which often characterizes fruit flavour.
( Fu et al., 2023 )
SDN1
CRISPR/Cas
Zhejiang University, China
University of Florida, USA
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research) Mt Albert
University of Auckland, New Zealand