Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Sdn Type

Displaying 41 results

Traits related to increased plant yield and growth

Only female flowers. Allows earlier production of hybrids, higher yield, and more concentrated fruit set.
( Hu et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences,
China
Increased spine density. The “numerous spines (ns)” cucumber varieties are popular in Europe and West Asia.
( Liu et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Rapid improvement of domestication traits and genes that control plant architecture, flower production and fruit size. Major productivity traits are improved in an orphan crop.
( Lemmon et al., 2018 )
SDN1
CRISPR/Cas
Cold Spring Harbor
The Boyce Thompson Institute
Cornell University, USA
Altered spike architecture and grain treshability to increase grain production.
( Liu et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Bigger grains, increased grain weight.
( Zhang et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Improvement for larger kernel and yield.
( Ma et al., 2015 )
SDN1
CRISPR/Cas
Northwest A &
F University
Chinese Academy of Agricultural Sciences, China
Increased yield potential trough improved nitrogen use efficiency. Enhanced tolerance to N starvation, and showed delayed senescence and increased grain yield in field conditions. Lowered use of N fertilizer.
( Zhang et al., 2021 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Zhengzhou University, China
Increased spikelet number and delayed heading date. Two traits that are crucial and correlated to yield in wheat.
( Chen et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )
SDN1
CRISPR/Cas
Sichuan Agricultural University, China
University of California, USA
Increased yield: plants produced more tillers and grains than azygous wild-type controls and the total yield was increased up to 15 per cent.
(Holubova et al., 2018)
SDN1
CRISPR/Cas
Palacký University
Centre of the Region Haná for Biotechnological and Agricultural Research, Czech Republic
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Traits related to biotic stress tolerance

Virus resistance: Immunity to cucumber vein yellowing virus infection (Ipomovirus) and resistance to the potyviruses Zucchini yellow mosaic virus and Papaya ring spot mosaic virus.
(Chandrasekaran et al., 2016)
SDN1
CRISPR/Cas
Volcani Center, Israel
High resistance to powdery mildew under semi-commercial growth conditions.
( Shnaider et al., 2022 )
SDN1
CRISPR/Cas
Agricultural Research Organization Volcani Center, Israel
Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Wang et al., 2014 )
SDN1
TALENs
Chinese Academy of Sciences, China
Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Zhang et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Fungal resistance: resistance to Fusarium graminearum. Fusarium head blight (FHB) is an economically important disease, affecting both yield and grain quality of maize, wheat and barley.
(Brauer et al., 2020)
SDN1
CRISPR/Cas
Ottawa Research and Development Centre, Canada
High level of powdery mildew resistance while maintaining normal crop
growth and yields.
( Li et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Robust rust resistance to pandemic stripe rust caused by Puccinia striiformis (Pst) without growth and yield penalty.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
Northwest A&
F University
Chinese Academy of Sciences, China
Fungal resistance: increased resistance against the fungus Puccinia striiformis f. sp. tritici (Pst). Wheat stripe rust is caused by Pst and is one of the most destructive wheat diseases, resulting in significant losses to wheat production worldwide.
(He et al., 2022)
SDN1
CRISPR/Cas
Northwest A&
F University
Hebei Agri cultural University, China

Traits related to improved food/feed quality

Regulate cucumber fruit wart formation. Warty fruit in cucumber is an important quality trait that greatly affects fruit appearance.
( Wang et al., 2021 )
SDN1
CRISPR/Cas
China Agricultural University, China
Boosted cytokinin biosynthesis and elevated cucumber fruit wart formation. Warty fruit is an important quality trait that greatly affects market value and fruit appearance.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Increased protein content and increased grain weight. Increase in grain protein content has a positive effect on flour protein content and gluten strength, two quality parameters.
( Zhang et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
University of Chinese Academy of Sciences
Shandong Normal University, China
Reduced gluten content. Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins.
( Sánchez-León,et al., 2017 )
SDN1
CRISPR/Cas
Instituto de Agricultura Sostenible (IASCSIC), Spain
University of Minnesota, USA
Modification of starch composition, structure and properties. Foods with a high amylose content (AC) and resistant starch (RS) offer potential to improve human health and lower the risk of serious non-infectious diseases.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences (CAAS)
Nanjing Agricultural University, China
Increased iron (Fe) and magnesium (Mn) content for biofortification: increasing the intrinsic nutritional value of crops.
(Connorton et al., 2017)
SDN1
CRISPR/Cas
John Innes Centre
University of East Anglia, UK
Increased grain number per spikelet.
( Zhang et al., 2019 )
SDN1
CRISPR/Cas
University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK
Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )
SDN1
CRISPR/Cas
University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France
Reduced accumulation of free asparagine, the precursor for acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods made from wheat.
( Raffan et al., 2021 )
SDN1
CRISPR/Cas
Rothamsted Research
University of Bristol, UK
Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan

Traits related to abiotic stress tolerance

Drought tolerance.
( Kim D et al,. 2018 )
SDN1
CRISPR/Cas
Montana State University, USA
Reduced cuticle permeability and enhanced drought tolerance.
( He et al., 2022 )
SDN1
CRISPR/Cas
Northwest A&
F University
USA
University of British Columbia, Canada
Increased drought tolerance.
( Abdallah et al., 2022 )
SDN1
CRISPR/Cas
Cairo University, Egypt
Crop Improvement and Genetics Unit, USA

Traits related to industrial utilization

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Peking University Institute of Advanced Agricultural Sciences
Peking University
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China
Fertility recovery of male sterility in wheat lines with excelling agronomic and economic traits for breeding purpose, as male-sterile plants cannot be used for selection.
( Tang et al., 2021 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
China Agricultural University, China
Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )
SDN1
CRISPR/Cas
The University of Adelaide, Australia
Huaiyin Normal University, China
Complete male sterility. The generation, restoration, and maintenance of male sterile lines are the key issues for large-scale commercial hybrid seed production.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Peking University Institute of Advanced Agricultural Sciences
School of Advanced Agriculture Sciences and School of Life Sciences
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China
Rapid generation of male sterile (MS) bread wheat. MS is an important tool in creating hybrid crop varieties that provide a yield advantage over traditional varieties by harnessing heterosis.
( Singh et al., 2021 )
SDN1
CRISPR/Cas
DuPont Pioneer, USA
Significantly longer seed dormancy period, may result in reduced pre-harvest sprouting of grains on spikes.
( Abe et al., 2019 )
SDN1
CRISPR/Cas
Institute of Crop Science
Okayama University
Yokohama City University
Institute of Agrobiological Sciences
Obihiro University of Agriculture and Veterinary Medicine, Japan

Traits related to herbicide tolerance

Nicosulfuron
( Zong et al., 2018 )

BE
Chinese Academy of Sciences, China
Nicosulfuron, mesosulfuron, imazapic, quizalofop
( Zhang et al., 2019 )

BE
Chinese Academy of Sciences
China Agricultural University, China
Dinitroanaline
( Han et al., 2021 )

BE
Shandong Normal University
Shandong Academy of Agricultural Sciences, China
Herbicide glyphosate tolerance.
( Arndell et al., 2019 )
SDN1
CRISPR/Cas
CSIRO
New South Wales Department of Primary Industries
The University of Adelaide, Australia