Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Displaying 48 results

Traits related to biotic stress tolerance

Viral resistance: increased resistance to infection with the potato virus Y (PVY) and tolerance to salt and osmotic stress. PVY is one of the most economically important potato pathogens
(Makhotenko et al., 2019)
SDN1
CRISPR/Cas
Russia Moscow State University, Russia
Doka Gene Technologies Ltd, USA
Reduced aphid damage to improve crop resistance to aphids or other insects. Restrict aphid sucking on watermelon.
( Li et al., 2021 )
SDN1
CRISPR/Cas
Beijing Academy of Agricultural and Forestry Sciences, China
Broad-spectrum resistance against multiple Potato virus Y (PVY)-strains.
( Noureen et al., 2022 )
SDN1
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences (PIEAS)
University Institute of Biochemistry and Biotechnology (UIBB), Pakistan
Viral resistance: reduced viral accumulation and amelioration of virus-induced symptoms by Potato Virus Y.
(Lucioli et al., 2022)
SDN1
CRISPR/Cas
ENEA
Council for Agricultural Research and Economics (CREA), Italy
National Agricultural Research and Innovation Centre, Hungary
Fungal resistance: Fusarium oxysporum f.sp. niveum (FON), one of the most devastaging diseases affecting watermelons. FON progresses along xylem vessels, causing the hollow and dried-out stems.
(Zhang et al., 2020)
SDN1
CRISPR/Cas
Jiangsu Academy of Agricultural Sciences
Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement, China
Viral resistance: Resistance to Potato Virus Y (PVY), one of the most devastating viral pathogens causing substantial harvest losses.
(Zhan et al., 2019)

CRISPR/Cas
Hubei University
Huazhong Agricultural University, China
Max‐Planck‐Institut für Molekulare Pflanzenphysiologie, Germany
Fungal resistance: increased resistance to Phytophthora infestans, causing late blight disease, the most serious disease of potato crops worldwide. The pathogen can infect the leaves, stems and tubers of potato plants. An unprotected field can be completely destroyed in several days.
(Kieu et al., 2021)
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
University of Copenhagen, Denmark
Visual detection of Alternaria solani, the causal agent of early blight in potato, which poses a persistant threat to potato production worldwide. The platform is specific, sensitive and suitable for high-throughput detection.
( Guo et al., 2023 )
SDN1
CRISPR/Cas
Jilin University
Jilin Agricultural University
Shenzhen Campus of Sun Yat-sen University, China
Viral resistance: Resistance against potato leaf roll virus, potato virus Y, potato virus X and potato virus S, which have been recognized as the major potato viruses.
(Zhan et al., 2023)
SDN1
CRISPR/Cas
Hubei University
Huazhong Agricultural University
Chinese Academy of Agricultural Sciences, China
Fungal resistance: Improved resistance against Phytophtora without affecting potato growth and development.
(Bi et al., 2023)
SDN1
CRISPR/Cas
China Agricultural University
South China Agricultural University
Shanghai Normal University
Nanjing Agricultural University, China
Sensitive and specific visual detection method for Acidovorax citrulli, an important seed-borne disease of the cucurbits.
( Wang et al., 2024 )
SDN1
CRISPR/Cas
Fuyang Normal University
Anhui Jianzhu University
Southern Subtropicals Grops Research Institute, China

Traits related to abiotic stress tolerance

Increased tolerance to drought trough reducing water loss. Tuber development.
( Gonzales et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Centro Nacional de Biotecnología – CSIC
Universidad Politécnica de Madrid (UPM), Spain
Increased tolerance to cold stress.
( Teper-Bamnolker et al., 2022 )
SDN1
CRISPR/Cas
The Volcani Institute
The Hebrew University of Jerusalem
Danziger Innovations Limited, Israel

Traits related to improved food/feed quality

Amylose-free starch in tubers.
( Toinga-Villafuerte et al., 2022 )
SDN1
CRISPR/Cas
Texas A&
M University, USA
Mutant cell lines doubled the accumulation level of anthocyanins biosynthesized. The production of these important pigments was stabilized over time.
( D'Amelia et al., 2022 )
SDN1
CRISPR/Cas
National Research Council of Italy
University of Naples Federico II
Council for Agricultural Research and Economics, Italy
Reduced browning and acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods and is regarded as a potential carcinogen and neurotoxin.
( Nguyen Phuoc Ly et al., 2023 )
SDN1
CRISPR/Cas
Murdoch University, Australia
Improved cold storage and processing traits: lower levels of reduced sugars
(Yasmeen et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab, Pakistan
Negligible levels of the possibly toxic steroidal glykoalkaloids (SGAs), but enhanced levels of steroidal saponins, which has pharmaceutically useful functions.
( Akiyama et al., 2017 )
SDN1
CRISPR/Cas
Kobe University
Riken Center for Sustainable Resource Science
Osaka University, Japan
Improved starch quality. Starch has many food and technical applications and is often modified to certain specifications.
( Andersson et al., 2017 )
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
Altered starch properties. Changes in amylopectin chain-lengths, starch granule initiation and branching frequency.
( Tuncel et al., 2019 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
Increased sucrose content.
( Ren et al., 2020 )
SDN1
CRISPR/Cas
Beijing Key Laboratory of Vegetable Germplasm Improvement
Capital Normal University
China Agricultural University, China
Cornell University
Robert W. Holley Center for Agriculture and Health, USA
Reduced steroidal glycoalkaloids.
( Yasumoto et al., 2019 )

TALENs
Osaka University
RIKEN Center for Sustainable Resource Science
Kobe University, Japan
Decreased seed size and promoted seed germination. To improve consumer experience for flesh-consumed watermelons, no (or small and sparse) seeds are better because the flesh portion is larger.
( Wang et al., 2021 )
SDN1
CRISPR/Cas
Beijing Key Laboratory of Vegetable Germplasm Improvement, China
Reduction of harmful ingredients: toxic steroidal glycoalkaloids (SGAs).
(Sawai et al., 2014)
SDN1
TALENs
RIKEN Center for Sustainable Resource Science
Chiba University, Japan
Complete abolition of glycoalkaloids, causing a bitter taste and toxic to various organisms.
( Nakayasu et al., 2018 )
SDN1
CRISPR/Cas
Kobe University, Japan
Starch with an increased amylose ratio and elongated amylopectin chains. In food products, high amylose content and long amylopectin chains contribute to a low glycaemic index (GI) after intake, playing a role in health benefits.
( Zhao et al., 2021 )
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Laboratorio de Agrobiotecnología (INTA), Argentina
Reduction of steroidal glycoalkaloids (SGAs). SGAs in most potato tissues are toxic to humans when the fresh weight is over 200mg/kg. High SGAs content also damage the quality of potato tubers.
( Zheng et al., 2021 )
SDN1
CRISPR/Cas
Qinghai University, China
Improved starch quality by reducing the levels of amylose, thus increasing the amylopectin content.
( Ali et al., 2023 )
SDN1
CRISPR/Cas
Agricultural Genetic Engineering Research Institute (AGERI)
Ain Shams University Faculty of Agriculture, Egypt
Amylose-free tubers.
( Abeuova et al., 2023 )
SDN1
CRISPR/Cas
National Center for Biotechnology (NCB)
L.N. Gumilyov Eurasian National University
Nazarbayev University, Kazakhstan

Traits related to increased plant yield and growth

Rapid improvement of domestication traits and genes that control plant architecture, flower production and fruit size. Major productivity traits are improved in an orphan crop.
( Lemmon et al., 2018 )
SDN1
CRISPR/Cas
Cold Spring Harbor
The Boyce Thompson Institute
Cornell University, USA
Increases size of starch granules. Granule size is a key parameter for industrial processing. Larger granules may increase yield during processing and it has been shown in sweet potato that smaller starch granules degrade faster than large granules, so larger granule tubers may be beneficial for storage.
( Pfotenhauer et al., 2023 )
SDN1
CRISPR/Cas
University of Tennessee, USA
Increased plant height, longer roots, smaller root growth angle and increased tuber weight.
( Zhao et al., 2024 )
SDN1
CRISPR/Cas
Yunnan Agricultural University
Chinese Academy of Sciences
Xuanhan County Plant Quarantine Station
Yuguopu District Agricultural Comprehensive Service Center
Ning'
er County Plant Protection and Plant Quarantine Station, China

Traits related to industrial utilization

Male sterility.
( Zhang et al., 2021 )
SDN1
CRISPR/Cas
Northwest A&
F University, China
Gynoecious phenotype: only female flowers. Advantageous trait for production of hybrid seed by bees under spatial isolation, because it avoids hand emasculation and hand pollination.
(Zhang et al., 2019)
SDN1
CRISPR/Cas
Beijing Key Laboratory of Vegetable Germplasm Improvement
Chinese Academy of Agricultural Engineering Planning and Design, China
Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Enciso-Rodriguez et al., 2021 )
SDN1
CRISPR/Cas
Michigan State University, USA
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Tian et al., 2023 )
SDN1
CRISPR/Cas
Beijing Key Laboratory of Vegetable Germplasm Improvement, China
Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Eggers et al., 2021 )
SDN3
CRISPR/Cas
Solynta
Wageningen University &
Research, The Netherlands

Traits related to herbicide tolerance

Herbicide tolerance: glyphosate
(Sauer et al., 2016)
SDN1
CRISPR/Cas
Cibus, USA
Imidizolinone
( Butler et al., 2016 )
SDN2
CRISPR/Cas
Michigan State University
University of Minnesota, USA
Imidizolinone
( Butler et al., 2016 )
SDN2
TALENs
Michigan State University
University of Minnesota, USA
Tribenuron
( Tian et al., 2018 )

BE
Beijing Academy of Agriculture and Forestry Sciences
China Agricultural University, China
Chlorsulfuron
( Veillet et al., 2019 )

BE
Université Rennes 1
INRA PACA
Université Paris-Saclay, France

Traits related to product color/flavour

Albino phenotype
( Bánfalvi et al., 2020 )
SDN1
CRISPR/Cas
NARIC Agricultural Biotechnology Institute, Hungary
Albino phenotype. Diversity in fruit color. Watermelon is an important fruit croup throughout the world.
( Tian et al., 2016 )
SDN1
CRISPR/Cas
Beijing Key Laboratory of Vegetable Germplasm Improvement
China Agricultural University
Beijing University of Agriculture, China
Alleviated browning of freshly cut potatoes.
( Shi et al., 2023 )
SDN1
CRISPR/Cas
Shandong Agricultural University, China

Traits related to storage performance

Improved cold storage and processing traits: reduced levels of acrylamide, reduced sugars.
(Clasen et al., 2017)
SDN1
TALENs
Cellectis Plant Science, USA
Reduced enzymatic browning. The formation of dark-colored precipitates in fruits and vegetables causes undesirable changes in organoleptic properties and the loss of nutritional quality.
( Gonzalez et al., 2020 )
SDN1
CRISPR/Cas
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Laboratorio de Agrobiotecnología (INTA)
Universidad Nacional de Mar del Plata, Argentina
Swedish University of Agricultural Sciences, Sweden
Decreased cold-induced sweetening of the potato tubers.
Cold-storage causes undesired sweetening which reduces the quality and the commercial value of the tubers.
( Hassan et al., 2023 )
SDN1
CRISPR/Cas
Agricultural Genetic Engineering Research Institute - Agricultural Research Center
Ain Shams University, Egypt