genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 34 results

Traits related to biotic stress tolerance

Fungal resistance: Enhanced resistance to the pathogen Sclerotinia sclerotiorum.
(Sun et al., 2018)

SDN1
CRISPR/Cas

Yangzhou University, China

Fungal resistance: contribute to Sclerotinia sclerotiorum resistance.
(Zhang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Visual detection of maize chlorotic mottle virus (MCMV), one of the important quarantine pathogens in China. This novel method is specific, rapid, sensitive and does not require special instruments and technical expertise.
( Duan et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Yazhou Bay Science and Technology City, China
Alexandria University, Egypt

Oilseed rape mutant with non-abscising floral organs. Clerotinia stem rot (SSR), caused by Sclerotinia sclerotiorum is a detrimental fungal disease for oilseed rape. Petal infection is crucial to the prevalence of SSR in oilseed rape. Oilseed rape varieties with abscission-defective ﬂoral organs were predicted to be less susceptible to Sclerotinia infection and to have a longer ﬂowering period to enhance tourism income.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Yangzhou University, China

Confered resistance to ear rot caused by Fusarium verticillioides.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

National Key Facility for Crop Gene Resources and Genetic Improvement
Hainan Yazhou Bay Seed Lab, China

Fungal resistance: increased resistance to southern leaf blight (SLB), caused by the necrotrophic fungal pathogen Cochliobolus heterostrophus (anamorph Bipolaris maydis). SLB is a major foliar disease which causes significant yield losses in maize worldwide.
(Chen et al., 2023)

SDN1
CRISPR/Cas

Northwest A&
F University, China
Corteva AgriscienceTM
USDA-ARS
North Carolina State University, USA

Fungal resistance: decreased susceptibility to Ustilago maydis, causing smut. The pathogen causes galls on all aerial parts of the plant, impacting crop yield and quality.
(Pathi et al., 2020)

SDN1
CRISPR/Cas

Leibniz Institute of Plant Genetics and Crop Plant Research, Germany

Fungal resistance: reduced susceptibility to Verticillium longisporum, a pathogen causing Verticillium stem striping. No fungicide treatments are currently available to control this disease.
(Pröbsting et al., 2020)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
NPZ Innovation GmbH, Germany

Visual detection of Fusarium temperatum, the causal agent of maize stalk rot disease which reduces grain yield and threatens food safety and quality.
This simple detection platform allows high-throughput testing with potential for applications in field detection.
( Li et al., 2023 )

SDN1
CRISPR/Cas

Jilin University
Jilin Agricultural University
Shenzhen Campus of Sun Yat-sen University, China

Detection of Fumonisin B1 (FB1), a common mycotoxin found in agricultural products. FB1 is highly toxic, which can cause oxidative stress response and has been listed as a class 2B carcinogen. The method wx is highly specific and sensitive for FB1, has a rather simple, convenient and fast workflow.
( Qiao et al., 2023 )

SDN1
CRISPR/Cas

Kunming University of Science and Technology, China

Visual detection of brassica yellows virus (BrYV), an economically important virus on cruciferous species. This assay allows for convenient, portable, rapid, low-cost, highly sensitive and specific detection and has great potential for on-site monitoring of BrYV.
( Xu et al., 2023 )

SDN1
CRISPR/Cas

Guizhou University, China

Rapid detection of toxigenic Fusarium verticillioides, a phytopathogenic fungus that causes Fusarium ear and stalk rot and poses a threat to maize yields. This accurate and portable detection equipment has great potential for detection of the pathogen, even in areas lacking proper lab equipment.
( Liang et al., 2023 )

SDN1
CRISPR/Cas

Institute of Food Science and Technology
North Minzu University
School of Food Science and Engineering, China
Gembloux Agro-Bio Tech, Belgium

Resistance against a protist pathogen: stable resistance against clubroot disease. Clubroot disease is caused by the protist Plasmodiophora brassicae Woronin and can result in a 10-15% yield loss in Brassica species as well as related crops.
(Hu et al., 2023)

SDN1
CRISPR/Cas

Saskatoon Research and Development Centre, Canada

Viral resistance: Increased resistance to a potyvirus sugarcane mosaic virus, which causes dwarf mosaic disease in maize, sugarcane and sorghum.
(Xie et al., 2024)

SDN1
CRISPR/Cas

China Agricultural University
Longping Agriculture Science Co. Ltd.
Chinese Academy of Sciences
Yunnan Agricultural University, China

Fungal resistance: Reduced susceptibility to Verticillium longisporum, fungal pathogen that causes stem striping in Brassica napus and leads to huge yield losses.
(Ye et al., 2024)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
Hohenlieth-Hof, NPZ Innovation GmbH, Germany
Aswan University, Egypt
Fujian Agriculture and Forestry University, China

Traits related to industrial utilization

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Fang et al., 2022 )

SDN1
CRISPR/Cas

University of Science and Technology Beijing
Beijing Solidwill Sci-Tech Co. Ltd., China

Enhanced haploid induction. Double haploid breeding based on in vivo haploid induction has been extensively used in maize breeding. The production of haploids depends on haploid inducers.
( Zhong et al., 2019 )

SDN1
CRISPR/Cas

China Agricultural University, China

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China
Wageningen University and Research, The Netherlands

Haploid induction.
( Li et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University
Longping Agriculture Science Co. Ltd., China

Induction of haploid plants for the development of good inbred lines for efficient and fast breeding.
( Liu et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Generation of male sterile (MS) lines. MS is a useful tool to harness hybrid vigor for hybrid seed production.
( Chen et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
China Agricultural University, China

Manipulation of flowering time to develop cultivars with desired maturity dates. Stabilization of flowering time and period supports efficient mechanised harvesting.
( Ahmar et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

SDN1
CRISPR/Cas

DuPont Pioneer, USA

SDN1
CRISPR/Cas

University of Science and Technology
Beijing, China
Beijing Solidwill Sci-Tech Co. Ltd, China

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Self-incompatibility to prevent inbreeding in hermaphrodite angiosperms via the rejection of self-pollen.
( Dou et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Shinoyama et al., 2020 )

SDN1
TALENs

Fukui Agricultural Experiment Station
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Japan Science and Technology Agency (JST)
Yokohama City University, Japan
Altai State University, Russia

Trait stacking. Modern agriculture demands crops carrying multiple traits.
( Ainley et al., 2013 )

SDN1
ZFN

Dow AgroSciences LLC
Sangamo BioSciences, Inc., USA

Haploid induction to accelerate breeding in crop plants.
( Rangari et al., 2023 )

SDN1
CRISPR/Cas

Punjab Agricultural University, India

Generating genic male sterility lines (GMS). GMS can promote heterosis in rapeseed. Compared with other approaches, GMS brings about nearly complete male sterility to a hybrid breeding program.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Northwest A&
F University
Hybrid Rapeseed Research Centre of Shaanxi Province, China

Pollen Self-Elimination, which prevents pollen transgene dispersal.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Northwest A&
F University
Hainan Yazhou Bay Seed Lab
Henan Jinyuan Seed Industry Co., China
International Maize and Wheat Improvement Center (CIMMYT), Mexico

Doubled haploids with increased leaf size. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Impens et al., 2023 )

SDN1
CRISPR/Cas

Ghent University
VIB-UGent Center for Plant Systems Biology
Flanders Research Institute for Agriculture, Fisheries and Food (ILVO), Belgium

Reversible complete male sterility. Very precise hormone mediated control of male fertility transition showed great potential for hybrid seed production in Brassica species crops.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs
Henan Normal University, China

Improved pollen viability.
( Lv et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences
Mianyang Normal University
South China Agricultural University, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to industrial utilization