Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Sdn Type

Displaying 26 results

Traits related to biotic stress tolerance

Enhanced resistance to powdery mildew.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences Institute of Tobacco Research, China
Increased resistance to drought stress by enhancing antioxidant capacity and defence system.
( Gao et al., 2022 )
SDN1
CRISPR/Cas
Henan Agricultural University
China Tobacco Sichuan Industrial Co., China
Viral resistance: resistance to potato virus Y (PVY), one of the most economically and scientifically important plant viruses, causing damaging diseases of cultivated tobacco around the world.
(Ruyi et al., 2021)
SDN1
CRISPR/Cas
Mudanjiang Teachers College
Jilin Normal University
Mudanjiang Tobacco Research Institute, China
Fungal resistance: enhanced resistance to Golovinomyces cichoracearum, which causes powdery mildew.
(Wang et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Linyi Tobacco Company
Tobacco Research Institute of Hubei Province
China Tobacco Hunan Industrial Co., China
Enhanced resistance to downy mildew pathogen.
( Hasley et al., 2021 )
SDN1
CRISPR/Cas
University of Hawaii at Manoa, USA
Viral resistance: Attenuated infection symptoms and reduced viral RNA accumulation, specific for the cucumber mosaic virus (CMV) or tobacco mosaic virus (TMV).
(Zhang et al., 2018)
SDN1
CRISPR/Cas
South China Agricultural University, China
University of Missouri, USA
Viral resistance: increased resistance against Tobacco Mosaic Virus (TMV).
(Jogam et al., 2023)
SDN1
CRISPR/Cas
Kakatiya University
Center of Innovative and Applied Bioprocessing (DBT-CIAB), India
University of Minnesota
East Carolina University, USA
Oomycete resistance: significantly reduced susceptibility to downy mildew disease (DM). DM is caused by Peronospora belbahrii, a worldwide threat to the basil industry.
(Zhang et al., 2021)
SDN1
CRISPR/Cas
The State University of New Jersey, USA
Viral resistance: highly resistant to viral infection with beet severe curly top virus (BSCTV), a geminivirus that can cause serious damage to many crop plants.
(Ji et al., 2015)
SDN1
CRISPR/Cas
University of Chinese Academy of Sciences, China

Traits related to abiotic stress tolerance

Improved Cadmium (Cd)-tolerance by reducing the Cd transport from vacuole to cytosol in tobacco leaves.
( Jia et al., 2022 )
SDN1
CRISPR/Cas
Henan Agricultural University
Xiamen University, China
Enhanced resistance to drought stress with increased osmotic adjustment, antioxidant activity, photosynthetic efficiency and decreased water loss rate.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Tobacco Research Institute
Key Laboratory of Tobacco Genetic Improvement and Biotechnology
Shenzhen Yupeng Technology Co.
Sichuan Tobacco Corporation, China
Increased drought tolerance.
( Xu et al., 2023 )
SDN1
CRISPR/Cas
R&
D Center of China Tobacco Yunnan Industrial Co. Ltd.
Sichuan Agriculture University, China
Reduced cadmium (Cd) accumulation and enhanceed Cd resistance. Cd accumulation in the edible parts of the plant pose potential risks to human health.
( Zheng et al., 2024 )
SDN1
CRISPR/Cas
Zhengzhou Tobacco Research Institute of CNTC
China Tobacco Yunnan Industrial Co. LTD
Beijing Life Science Academy (BLSA)
Zhengzhou University, China

Traits related to improved food/feed quality

Improved cadmium tolerance by reducing the Cd transport from vacuole to cytosol in tobacco leaves.
( Jia et al., 2022 )
SDN1
CRISPR/Cas
Henan Agricultural University
Xiamen University, China
Ultra-low nicotine level
( Burner et al., 2022 )
SDN1
CRISPR/Cas
North Carolina State University, USA
Increased potassium concentrations (K+). Potassium is crucial for improving the quality of tobacco.
( Gao et al., 2024 )
SDN1
CRISPR/Cas
Yunnan Academy of Tobacco Agricultural Sciences/National Tobacco Genetic Engineering
Research Center
Chinese Academy of Agricultural Sciences, China

Traits related to increased plant yield and growth

Significantly higher potassium accumulation. Potassium ions are essential nutrients for growth and development of tobacco.
( Gao et al., 2024 )
SDN1
CRISPR/Cas
Yunnan Academy of Tobacco Agricultural Sciences/National Tobacco Genetic Engineering Research Center
Chinese Academy of Agricultural Sciences, China

Traits related to industrial utilization

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Cytoplasmic male sterility.
( Chang et al., 2022 )
SDN1
CRISPR/Cas
Northwest Institute of Plateau Biology Chinese Academy of Sciences, China
Accumulate low levels of alkaloids. Nicotine is the most abundant alkaloid produced in tobacco plants. Switching to cigarettes containing levels of nicotine below the level of sustaining an addiction response will smoke less and/or find it easier to quit. Possibly, the US Food and Drug Administration (FDA) may mandate such reductions in future cigarette products.
( Smith et al., 2022 )
SDN1
CRISPR/Cas
North Carolina State University, USA

Traits related to product color/flavour

Albino phenotype.
( Wang et al., 2018 )
SDN1
CRISPR/Cas
Provincial Key Laboratory of Applied Botany
Guangdong Provincial Key Laboratory of Applied Botany
University of Chinese Academy of Sciences, China
Pale purple phenotype due to dramatic decrease of anthocyanins content.
( Duan et al., 2023 )
SDN1
CRISPR/Cas
College of Horticulture, China
Color modification due to reduced anthocyanin accumulation.
( Klimek-Chodacka et al., 2018 )
SDN1
CRISPR/Cas
University of Agriculture in Krakow, Poland
East Carolina University
University of Maryland, USA
Purple color.
( Xu et al., 2019 )
SDN1
CRISPR/Cas
Nanjing Agricultural University, China
Reduced citrate content. Citrate is a common primary metabolite which often characterizes fruit flavour.
( Fu et al., 2023 )
SDN1
CRISPR/Cas
Zhejiang University, China
University of Florida, USA
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research) Mt Albert
University of Auckland, New Zealand
Color change of the taproot from orange to pink-orange and slightly higher content of α-carotene in the taproot.
( Li et al., 2022 )
SDN1
CRISPR/Cas
Nanjing Agricultural University
Chinese Academy of Agricultural Science, China