genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 42 results

Traits related to biotic stress tolerance

Visual detection of brassica yellows virus (BrYV), an economically important virus on cruciferous species. This assay allows for convenient, portable, rapid, low-cost, highly sensitive and specific detection and has great potential for on-site monitoring of BrYV.
( Xu et al., 2023 )

SDN1
CRISPR/Cas

Guizhou University, China

Fungal resistance: Improved resistance against Phytophtora without affecting potato growth and development.
(Bi et al., 2023)

SDN1
CRISPR/Cas

China Agricultural University
South China Agricultural University
Shanghai Normal University
Nanjing Agricultural University, China

Oilseed rape mutant with non-abscising floral organs. Clerotinia stem rot (SSR), caused by Sclerotinia sclerotiorum is a detrimental fungal disease for oilseed rape. Petal infection is crucial to the prevalence of SSR in oilseed rape. Oilseed rape varieties with abscission-defective ﬂoral organs were predicted to be less susceptible to Sclerotinia infection and to have a longer ﬂowering period to enhance tourism income.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Yangzhou University, China

Viral resistance: Resistance against potato leaf roll virus, potato virus Y, potato virus X and potato virus S, which have been recognized as the major potato viruses.
(Zhan et al., 2023)

SDN1
CRISPR/Cas

Hubei University
Huazhong Agricultural University
Chinese Academy of Agricultural Sciences, China

Fungal resistance: contribute to Sclerotinia sclerotiorum resistance.
(Zhang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Visual detection of Alternaria solani, the causal agent of early blight in potato, which poses a persistant threat to potato production worldwide. The platform is specific, sensitive and suitable for high-throughput detection.
( Guo et al., 2023 )

SDN1
CRISPR/Cas

Jilin University
Jilin Agricultural University
Shenzhen Campus of Sun Yat-sen University, China

Fungal resistance: Enhanced resistance to the pathogen Sclerotinia sclerotiorum.
(Sun et al., 2018)

SDN1
CRISPR/Cas

Yangzhou University, China

Fungal resistance: Reduced susceptibility to Verticillium longisporum, fungal pathogen that causes stem striping in Brassica napus and leads to huge yield losses.
(Ye et al., 2024)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
Hohenlieth-Hof, NPZ Innovation GmbH, Germany
Aswan University, Egypt
Fujian Agriculture and Forestry University, China

Viral resistance: Resistance to Potato Virus Y (PVY), one of the most devastating viral pathogens causing substantial harvest losses.
(Zhan et al., 2019)

CRISPR/Cas

Hubei University
Huazhong Agricultural University, China
Max‐Planck‐Institut für Molekulare Pflanzenphysiologie, Germany

Fungal resistance: reduced susceptibility to Verticillium longisporum, a pathogen causing Verticillium stem striping. No fungicide treatments are currently available to control this disease.
(Pröbsting et al., 2020)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
NPZ Innovation GmbH, Germany

Traits related to abiotic stress tolerance

Reduction in cadmium accumulation. Cadmium is a heavy metal, harmful for human health.
( Yao et al., 2022 )

SDN1
CRISPR/Cas

Sichuan University
Science and Technology Innovation Center of Sichuan Modern Seed Industry Group, China

Improved drought tolerance.
( Linghu et al., 2023 )

SDN1
CRISPR/Cas

Hybrid Rapeseed Research Center of Shaanxi Province
Northwest A &
F University, China

Enhanced drought tolerance
( Wu et al., 2020 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Traits related to improved food/feed quality

Yellow-seed production, a desirable trait with great potential for improving seed quality in Brassica crops. The formation of seed colour is due to the deposition of the oxidized form of a flavonoid, called proanthocyanidins (PA). Yellow seeds have a higher oil content.
( Zhai et al., 2019 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia

Modified fatty acid profile: increased oleic acid, decreased linoleic and linolenic acid content.
(Huang et al., 2020)

SDN1
CRISPR/Cas

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, China

Increasing seed oil content (SOC).
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Huazhong University of Science and Technology, China

Improved fatty acid content: increased content of oleic acid, reduced erucic acid levels and slightly decreased polyunsaturated fatty acids content. Fatty acid composition is important for human health and shelf life.
(Shi et al., 2022)

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences, China

Altered lignin composition: decreased syringyl monolignol / guaiacylmonolignol (S/G) ratio. The monolignol ratio has been proposed to affect biomass recalcitrance and the resistance to plant disease.
(Cao et al., 2021)

SDN1
CRISPR/Cas

SouthwestUniversity, China
University of Wisconsin, USA

Reduction of steroidal glycoalkaloids (SGAs). SGAs in most potato tissues are toxic to humans when the fresh weight is over 200mg/kg. High SGAs content also damage the quality of potato tubers.
( Zheng et al., 2021 )

SDN1
CRISPR/Cas

Qinghai University, China

Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Sashidhar et al., 2020 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Max-Planck-Institute for Evolutionary Biology, Germany

Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
National Research Council Canada, Canada

Low erucic acid (EA) content. Composition of fatty acids affects the edible and processing quality of vegetable oils. EA is potentially to cause health problems.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Traits related to increased plant yield and growth

Semi-dwarf phenotype and compact architecture to increase yield. Plant height and branch angle are the major architectural factors determining yield.
( Fan et al., 2021 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs, China
Wilkes University, USA

Improve plant architecture to increase yield. Plant height and branch number are directly correlated with yield.
( Zheng et al., 2020 )

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Wilkes University, USA

Increased seeds number per husk, higher seed weight.
( Yang et al., 2018 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Increased plant height, longer roots, smaller root growth angle and increased tuber weight.
( Zhao et al., 2024 )

SDN1
CRISPR/Cas

Yunnan Agricultural University
Chinese Academy of Sciences
Xuanhan County Plant Quarantine Station
Yuguopu District Agricultural Comprehensive Service Center
Ning'
er County Plant Protection and Plant Quarantine Station, China

Increased seed oil content (SOC). SOC is a major determinant of yield and quality.
( Karunarathna et al., 2020 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel, Germany
Zhejiang University, China

Increased shatter resistance to avoid seed loss during mechanical harvest.
( Braatz et al., 2017 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel, Germany

Early-flowering varieties. The timing of flowering is an important event in the life cycle of flowering plants.
( Jiang et al., 2018 )

SDN1
CRISPR/Cas

Hunan Agricultural University, China
Université de Strasbourg, France

Traits related to industrial utilization

Self-incompatibility to prevent inbreeding in hermaphrodite angiosperms via the rejection of self-pollen.
( Dou et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Male sterility.
( Shen et al., 2024 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory, China

Manipulation of flowering time to develop cultivars with desired maturity dates. Stabilization of flowering time and period supports efficient mechanised harvesting.
( Ahmar et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Male sterility.
( Tu et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang University
Jiaxing Academy of Agricultural Sciences, China

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China
Wageningen University and Research, The Netherlands

Generating genic male sterility lines (GMS). GMS can promote heterosis in rapeseed. Compared with other approaches, GMS brings about nearly complete male sterility to a hybrid breeding program.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Northwest A&
F University
Hybrid Rapeseed Research Centre of Shaanxi Province, China

Reversible complete male sterility. Very precise hormone mediated control of male fertility transition showed great potential for hybrid seed production in Brassica species crops.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs
Henan Normal University, China

Traits related to herbicide tolerance

Tribenuron methyl
( Wu et al., 2020 )

Yangzhou University
Shanghai Normal University, China

Glyphosate
( Wang et al., 2021 )

CRISPR/Cas

Huazhong Agricultural University
Anhui Academy of Agricultural Sciences, China

Traits related to product color/flavour

Yellow colored seed.
( Huang et al., 2023 )

SDN1
CRISPR/Cas

Hunan Academy of Agricultural Sciences
Hunan University of Science and Technology
Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, China

Altered color of petals and leaves.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory, China

Alleviated browning of freshly cut potatoes.
( Shi et al., 2023 )

SDN1
CRISPR/Cas

Shandong Agricultural University, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour