genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 52 results

Traits related to abiotic stress tolerance

Enhanced salinity tolerance.
( Zhang et al., 2019 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Shanghai Agrobiological Gene Center, China

Enhanced chilling tolerance at seedling stage without yield loss.
( Deng et al., 2024 )

SDN1
CRISPR/Cas

Hunan Agricultural University
Hunan Academy of Agricultural Sciences
Yuelushan Laboratory, China

Reduced uptake of lead (Pb). Lead is one of the most toxic metals affecting human health globally and food is an important source of chronic Pb exposure in humans.
( Chang et al., 2022 )

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Enhanced resistance to salt and oxidative stress and increased grain yield.
( Alfatih et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Enhanced cadmium resistance with reduced cadmium accumulation in roots and shoots. Cadmium is a heavy metal, harmful for human health.
( Dang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University/Key Laboratory of Northern geng Super Rice Breeding, China

Better salinity tolerance.
( Ma et al., 2022 )

SDN1
CRISPR/Cas

Ningbo Academy of Agricultural Sciences
Nanjing Agricultural University, China

Enhanced the tolerance of plants to salt (NaCl), the stress hormone abscisic acid (ABA), dehydration and polyethylene glycol (PEG) stresses.
( Yue et al., 2020 )

SDN1
CRISPR/Cas

Zhejiang University
Hunan Agricultural University, China

Early heading phenotype that escapes from cold stress and achieves high yield potential.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Institute of Lianyungang Agricultural Science of Xuhuai Area/Lianyungang Institute of Agricultural Sciences
Chinese Academy of Agricultural Sciences, China

Improved drought tolerance and yield.
( Usman et al., 2020 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Arsenic (As) tolerance. As is toxic to organisms and elevated As accumulation may pose health risks to humans.
( Duan et al., 2015 )

SDN1
CRISPR/Cas

Anhui Academy of Agricultural Sciences, China

Improved salt stress resistance. Significant increase in the shoot weight, the total chlorophyll content, and the chlorophyll fluorescence under salt stress. Also high antioxidant activities coincided with less reactive oxygen species (ROS).
( Shah Alam et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University, China
Taif University, Saudi Arabia
Alexandria University, Egypt

Increased tolerance to cadmium toxicity.
( Yue et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University
Hangzhou Academy of Agricultural Sciences, China

Curled leaf phenotype and improved drought tolerance.
( Liao et al., 2019 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Salt tolerance during the seedling stage.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

Hubei Academy of Agricultural Sciences
Huazhong Agriculture University
Hubei Hongshan Laboratory, China

Salt tolerance.
( Duan et al,. 2016 )

SDN1
CRISPR/Cas

Anhui Academy of Agricultural Sciences, China

More tolerant to chilling stress: increased survival rate, decreased membrane permeability, and reduced lipid peroxidation.
(Xu et al., 2022)

SDN1
CRISPR/Cas

Henan University of Science and Technology
Chinese Academy of Sciences, China

Reduced cadmium content. Cadmium poses a health treat, as it is a highly toxic heavy metal for most living organisms.
( Hao et al., 2022 )

SDN1
CRISPR/Cas

Hunan University of Arts and Science
Hunan Normal University, China

Drought tolerance.
( Zhao et al., 2022 )

SDN1
CRISPR/Cas

Hebei Normal University
University of Chinese Academy of Sciences, China

Enhanced rice salinity tolerance and absisic acid hypersensitivity.
( Yan et al., 2023 )

SDN1
CRISPR/Cas

Nanchang University, China

Improved rice growth with increased plant height, biomass, and chlorophyll content but with a lower degree of oxidative injury and Cd accumulation.
( Cao et al., 2022 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Jiangsu Academy of Agricultural Sciences, China

Potassium deficiency tolerance and contribution to stomatal closure.
( Mao et al., 2016 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Fujian Academy of Agricultural Sciences
National Center of Rice Improvement of China
National Engineering Laboratory of Rice
South Base of National Key Laboratory of Hybrid Rice of China, China

Increased tolerance to low temperatures.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Tianjin Academy of Agricultural Sciences
Nankai University
University of Electronic Science and Technology of China, China

Enhances adaptation to direct-seeding on wet land and tolerance to drought stress in rice. Water stress is the most important factor limiting rice agriculture by either floods or drought.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Shanghai Agrobiological Gene Center, China

Decreased Cadmium (Cd) accumulation. Consumption of crops that absorb Cd from the soil can cause serious health problems in humans.
( He et al., 2024 )

SDN1
CRISPR/Cas

Yunnan Agricultural University, China

Increased water-deficit tolerance.
( Lv et al., 2022 )

SDN1
CRISPR/Cas

Chongqing University, China

Improved yield and cold tolerance. High yield and high cold tolerance were often antagonistic to each other.
( Zeng et al., 2020 )

SDN1
CRISPR/Cas

College of Life Sciences, Wuhan University, China

Salt-tolerant plants.
( Jingfang et al., 2023 )

SDN1
CRISPR/Cas

Lianyungang Academy of Agricultural Science
Nanjing Agricultural University
Jiangsu Academy of Agricultural Sciences, China

Chilling tolerance.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Jilin University, China

Drought tolerance and abscisic acid sensitivity.
( Lou et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Traits related to industrial utilization

Prolonged basic vegetative growth periods for flexible cropping systems in southern China, as well as in other low-latitude regions. Most of the mid-latitude varities were sensitive to temperature or photoperiod, resulting in low grain yield when cultivated in low-latitude regions.
( Wu et al., 2020 )

SDN1
CRISPR/Cas

Fujian Agricultural and Forestry University
Fujian Academy of Agricultural Sciences
Minjiang University, China

Thermosensitive genic male sterile lines with high blast resistance and fragrance quality. Resources for hybrid rice breeding.
( Liang et al., 2022 )

SDN1
CRISPR/Cas

China National Rice Research Institute, China

Development of commercial thermosensitive genic male sterile lines to accelerate hybrid rice breeding.
( Zhou et al., 2016 )

SDN1
CRISPR/Cas

State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources
Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions
South China Agricultural University
China National Hybrid Rice R&
D Center, China

Early heading: in regions with short growing seasons, early maturing varieties to escape frost damage are required.
(Sohail et al., 2022)

SDN1
CRISPR/Cas

China National Rice Research Institute
Northern Center of China National Rice Research Institute
Zhejiang A&
F University, China
Mir Chakar Khan Rind University
Agriculture Research System Khyber, Pakistan
Ministry of Agriculture, Bangladesh
Agriculture Research Center, Egypt

Rescued male fertility. Hybrids between divergent populations commonly show hybrid sterility; this reproductive barrier hinders hybrid breeding of the japonica and indica rice subspecies.
( Shen et al., 2017 )

SDN1
CRISPR/Cas

State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources
Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions
South China Agricultural University, China

Enhanced biomass saccharification by altered lignin biosynthesis. The intrinsic recalcitrance of lignocellulose residues requires high energy input for bioethanol production.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei University of Arts &
Science
Guangxi University, China

Enhanced genetic recombination frequency to increase genetic diversity and disrupting genetic interference.
( Liu et al., 2021 )

SDN1
CRISPR/Cas

China National Rice Research Institute
Chinese Academy of Sciences
Chinese Academy of Agricultural Sciences, China

Male sterility and decreased total fatty acid content in the anther.
( Basnet et al., 2019 )

SDN1
CRISPR/Cas

Zhejiang University
Yangtze University, China

Enhanced biomass saccharification by remodelling of cell wall composition.
( Dang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University/Key Laboratory of Northern geng Super Rice Breeding, China

Generating male sterility lines (MSL). MS is the absence or non-function of pollen grain in plant or incapability of plants to produce or release functional pollen grains. Using MS lines eliminates the process of mechanical emasculation in hybrid seed production.
( Zou et al., 2017 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Peking University Institute of Advanced Agricultural Sciences
School of Advanced Agriculture Sciences and School of Life Sciences
Peking University
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement,China

SDN1
CRISPR/Cas

University of Science and Technology Beijing
Yili Normal University
Zhongzhi International Institute of Agricultural Biosciences
Beijing Solidwill Sci-Tech Co. Ltd., China

Late flowering time.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University
China Zhejiang Zhengjingyuan Pharmacy Chain Co., Ltd. &
Hangzhou Zhengcaiyuan Pharmaceutical Co., China

Generation of a new thermo-sensitive genic male sterile rice line for hybrid breeding of indica rice.
( Barman et al., 2019 )

SDN1
CRISPR/Cas

China National Rice Research Institute, China
Bangladesh Rice Research Institute, Bangladesh

Rescued hybrid female fertility. Hybrids between divergent populations commonly show hybrid sterility; this reproductive barrier hinders hybrid breeding of the japonica and indica rice subspecies.
( Guo et al., 2023 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs
Guangdong Key Laboratory of New Technology in Rice Breeding
Guangdong Academy of Agricultural Sciences
South China Agricultural University, China

Wine fermentation: minimize ethyl carbamate (EC) accumulation. EC is a potential carcinogen to humans. EC is mainly produced through the reaction between urea and ethanol during the Chinese wine brewing process.
(Wu et al., 2020)

SDN2
CRISPR/Cas

Jiangnan University
Zhejiang Shuren University, China

Creation of photoperiod-/thermo-sensitive genic male-sterile (P/TGMS) lines, important for commercial rice breeding. P/TGMS rice lines are useful germplasm resources for two-line hybrid breeding.
( Lan et al., 2019 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Enabled clonal reproduction trough seeds. Application of the method may enable self-propagation of a broad range of elite F1 hybrid crops.
( Wang et al., 2019 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
Université Paris-Saclay, France

Confer male sterility for hybrid seed production. Male sterility is an important trait, especially for self-pollinated crops such as rice.
( Ma et al., 2019 )

SDN1
CRISPR/Cas

South China Agricultural University, China

Regulation of flowering time and drought tolerance: flowered 9.6 and 5.8 days earlier.
(Gu et al., 2022)

SDN1
CRISPR/Cas

Yangzhou University, China

Induction of haploid plants and a reduced seed set for rice breeding.
( Yao et al., 2018 )

SDN2
CRISPR/Cas

ZhongGuanCun Life Science Park, China
Syngenta India Limited
Technology Centre
Medchal Mandal, India
Syngenta Crop Protection
LLC
Research Triangle Park, USA

Early heading: timing of heading is crucial for the reproduction and the geographical expansion of cultivation of rice.
(Sun et al., 2022)

SDN1
CRISPR/Cas

China National Rice Research Institute
Shanghai Academy of Agricultural Sciences
Northern Center of China National Rice Research Institute
Xuzhou Institute of Agricultural Sciences, China

Early maturity of rice varieties. Rice is a tropical short-day plant. The northward cultivation in China is accompanied with daylength extension and temperature decrease, which are unfavorable for rice, to complete flowering and seed setting.
( Li et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Jiangsu Academy of Agricultural Sciences, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to abiotic stress tolerance

Traits related to industrial utilization