genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 94 results

Traits related to biotic stress tolerance

Highly significant reduction in susceptibility to fire blight, caused by the bacterium Erwinia amylovora. Apple is one of the most cultivated fruit crops throughout the temperate regions of the world.
( Pompili et al., 2020 )

SDN1
CRISPR/Cas

Università degli Studi di Udine
Fondazione Edmund Mach, Italy

Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)

SDN1
CRISPR/Cas

Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands

Broad-spectrum disease resistance without yield loss.
( Sha et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Chengdu Normal University
Jiangxi Academy of Agricultural Sciences
Anhui Agricultural University
BGI-Shenzhen
Northwest A&
F University
Shandong Academy of Agricultural Sciences, China
Université de Bordeaux, France
University of California
The Joint BioEnergy Institute, USA
University of Adelaide, Australia

Oomycete resistance: significantly reduced susceptibility to downy mildew disease (DM). DM is caused by Peronospora belbahrii, a worldwide threat to the basil industry.
(Zhang et al., 2021)

SDN1
CRISPR/Cas

The State University of New Jersey, USA

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zhou et al., 2015)

SDN1
CRISPR/Cas

Iowa State University, USA

Bacterial resistance: resistance to different pathogens including Xanthomonas spp., P. syringae and P. capsici.
(de Toledo Thomazella et al., 2016)

SDN1
CRISPR/Cas

University of California, USA

Viral resistance: increased resistance to chickpea chlorotic dwarf virus (CpCDV).
(Malik et al., 2023)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Nematode resistance: resistance against soybean cyst nematode. Plant-parasitic nematode pests result in billions of dollars in realized annual losses worldwide.
(Usovsky et al., 2023)

SDN1
CRISPR/Cas

University of Missouri
University of Georgia
Beltsville Agricultural Research Center, USA

Bacterial resistance: improved resistance to Xanthomonas oryzae, which causes bacterial blight, a devastating rice disease resulting in yield losses.
(Oliva et al., 2019)

SDN1
CRISPR/Cas

International Rice Research Institute, Philippines
University of Missouri
University of Florida
Iowa State University
Donald Danforth Plant Science Center, USA
Université Montpellier, France
Heinrich Heine Universität Düsseldorf
Max Planck Institute for Plant Breeding Research
Erfurt University of Applied Sciences, Germany
Nagoya University, Japan

Visualization of the early stages of Cassava bacterial blight (CBB) infection in vivo. CBB is caused by Xanthomonas axonopodis pv. Manihotis.
( Veley et al., 2021 )

SDN2
CRISPR/Cas

Donald Danforth Plant Science Center, USA
National Root Crops Research Institute, Nigeria

Bacterial resistance: Resistance against African Xanthomonas oryzae isolates, causing agents of bacterial blight. Bacterial blight threatens rice populations in Asia and West Africa.
(Li et al., 2024)

University of Missouri
Donald Danforth Plant Science Center, USA
Department of Nanjing Agricultural University, China

Oomycete resistance: resistance against downly mildew disease (DM). DM is caused by Peronospora belbahrii, a worldwide threat to the basil industry.
(Laura et al., 2023)

SDN1
CRISPR/Cas

Research Centre for Vegetable and Ornamental Crops
Institute of Agricultural Biology and Biotechnology
Institute for Sustainable Plant Protection
Research Centre for Olive Fruit and Citrus Crops
University of Pisa
Center for Agricultural Experimentation and Assistance
Institute of Biosciences and Bioresources, Italy

Resistance to parasitic weed: Striga spp. The parasitic plant reduces yields of cereal crops worldwide.
(Hao et al., 2023)

SDN1
CRISPR/Cas

University of Nebraska-Lincoln
Pennsylvania State University, USA
International Maize and Wheat Improvement Center (CIMMYT), Senegal
Kenyatta University, Kenya

Bacterial resistance: Enhanced resistance against hemibiotrophic pathogens M. oryzae and Xanthomonas oryzae pv. oryzae (but increased susceptibility to Cochliobolus miyabeanus)
(Kim et al., 2022)

SDN1
CRISPR/Cas

Seoul National University
Kyung Hee University, South Korea
Pennsylvania State University, USA

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Shan et al., 2013)

SDN1
TALENs

Chinese Academy of Sciences, University of Electronic Science and Technology of China, China
University of Minnesota, USA

Bacterial resistance: Enhanced resistance against Candidatus Liberibacter spp., which causes significant economic losses globally.
(Ramasamy et al., 2024)

SDN1
CRISPR/Cas

Texas A&
M AgriLife Research and Extension Center
Texas A&
M University
Texas A&
M AgriLife, USA

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Li et al., 2013)

SDN1
TALENs

Iowa State University, USA
Guangxi University, China

Viral resistance: reduced viral accumulation and amelioration of virus-induced symptoms by Potato Virus Y.
(Lucioli et al., 2022)

SDN1
CRISPR/Cas

ENEA
Council for Agricultural Research and Economics (CREA), Italy
National Agricultural Research and Innovation Centre, Hungary

Viral resistance: increased resistance against Tobacco Mosaic Virus (TMV).
(Jogam et al., 2023)

SDN1
CRISPR/Cas

Kakatiya University
Center of Innovative and Applied Bioprocessing (DBT-CIAB), India
University of Minnesota
East Carolina University, USA

Fungal resistance: increased resistance to southern leaf blight (SLB), caused by the necrotrophic fungal pathogen Cochliobolus heterostrophus (anamorph Bipolaris maydis). SLB is a major foliar disease which causes significant yield losses in maize worldwide.
(Chen et al., 2023)

SDN1
CRISPR/Cas

Northwest A&
F University, China
Corteva AgriscienceTM
USDA-ARS
North Carolina State University, USA

Fungal resistance: increased resistance to Phytophthora tropicalis. Severe outbreaks can destroy all cacao fruit on a farm. Each year, global cacao production is destroyed with 20-30% by pathogens.
(Fister et al., 2018)

SDN1
CRISPR/Cas

Pennsylvania State University, USA

Fungal resistance: Decreased susceptibility against sheath blight disease caused by Rhizoctonia solani AGI-1A and is one of the three major rice diseases. Sheath blight disease can cause severe yield losses.
(Zhao et al., 2024)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hebei Agricultural University
Agricultural College of Yangzhou University, China
The Ohio State University, USA

Viral resistance: increased control on viral pathogen Banana streak virus (BSV). The BSV integrates in the banana host genome as endogenous BSV (eBSV). When banana plants are stressed, the eBSV produces infectious viral particles and thus the plant develops disease symptoms.
(Tripathi et al., 2019)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya
University of California, USA

Viral resistance: Reduced viral load and symptoms after bean yellow dwarf virus (BeYDV) infection.
(Baltes et al., 2015)

SDN1
CRISPR/Cas

University of Minnesota
The Ohio State University, USA
Institute of Biophysics ASCR, Czech Republic

Bacterial resistance: Xanthomonas citri, causing citrus canker, one of the most serious diseases affecting the global citrus industry.
(Jia et al., 2020)

SDN1
CRISPR/Cas

University of Florida, USA

Bacterial resistance: resistance to Xanthomonas citri, a pathogen causing citrus canker. Citrus canker is one of the most devastating citrus diseases worldwide, causing canker symptoms. Generating disease-resistant varieties is one of the most efficient and environmentally friendly measures for controlling canker.
(Jia et al., 2021)

SDN1
CRISPR/Cas

University of Florida
Citrus Research and Education Center, USA

Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

Fungal resistance: Enhanced resistance against powdery mildew, caused by Oidium neolycopersici, which is a major concern for the productivity of tomato plants.
(Li et al., 2024)

SDN1
CRISPR/Cas

University of Torino, Italy
Wageningen University &
Research, The Netherlands
Shanxi Agricultural University, China

Fungal resistance: Enhanced resistance to powdery mildew, a fungal disease causing great losses in soybean yield and seed quality.
(Bui et al., 2023)

SDN1
CRISPR/Cas

Institute of Biotechnology
University of Science and Technology of Hanoi
Vietnam Academy of Science and Technology
Vietnam Academy of Agriculture Science, Vietnam
Washington University in St. Louis
University of Missouri, USA

Enhanced resistance to downy mildew pathogen.
( Hasley et al., 2021 )

SDN1
CRISPR/Cas

University of Hawaii at Manoa, USA

Viral resistance: Attenuated infection symptoms and reduced viral RNA accumulation, specific for the cucumber mosaic virus (CMV) or tobacco mosaic virus (TMV).
(Zhang et al., 2018)

SDN1
CRISPR/Cas

South China Agricultural University, China
University of Missouri, USA

Bacterial resistance: resistance against bacterial spot disease, caused by Xanthomonas species, which could be a devastating to tomato as well as pepper.
(Ortega et al., 2024)

SDN1
CRISPR/Cas

University of California
University of Florida, USA

Fungal resistance: improved resistance to necrotrophic fungus Botrytis cinerea.
(Jeon et al., 2020)

SDN1
CRISPR/Cas

Stanford University, UK
L’Oreal, France
Howard Hughes Medical Institute, USA

Fungal resistance: Reduced pathogenicity to the oomycete Phytophthora palmivora, a destructive pathogen that infects all parts of papaya plants. Increased papain sensitvity of in-vitro growth. Papaya fruits contain papain, a cysteine protease that mediates plant defense against pathogens and insects.
(Gumtow et al., 2018)

SDN1
CRISPR/Cas

University of Hawaii at Manoa, USA

Effective detection of a resistance-breaking strain of tomato spotted wilt virus (TSWV). TSWV causes a great threat to various food crops globally and can cause devastating epidemics.
( Shymanovich et al., 2024 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Fungal resistance: enhanced resistance to powdery mildew (Erysiphe necator), a major fungal disease, threatening one of the most economically valuable horticular crops.
(Wan et al., 2020)

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Northwest A&
F University
University of Maryland College Park, USA

Bacterial resistance: Xanthomonas citri, causing citrus canker, one of the most serious diseases affecting the global citrus industry. Citrus is the most produced fruit in the world.
(Jia et al., 2016)

SDN1
CRISPR/Cas

University of Florida, USA

Bacterial resistance: Increased resistance to Erwinia amylovora, causing fire blight disease that threatens the apple and a wide range of ornamental and commercial Rosaceae host plants.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

Fungal resistance: increased tolerance to Late Blight disease, which could be devastating to tomato yields.
(Maioli et al., 2024)

SDN1
CRISPR/Cas

University of Torino, Italy
Ingeniero Fausto Elio/n, Spain
Wageningen University &
Research,

Fungal resistance: broad-spectrum stress tolerance including Pseudoperonospora cubernsis (P. cubensis) resistance. P. cubensis is the causal agent of cucurbit downy mildew, responsible for devastating losses worldwide of cucumber, cantaloupe, pumpkin, watermelon and squash.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Mutants were compromised in infectivity of Phytophthora palmivora, a destructive oomycete plant pathogen with a wide host range
( Pettongkhao et al., 2022 )

SDN1
CRISPR/Cas

Prince of Songkla University, Thailand
University of Hawaii at Manoa
East-West Center, USA
Sainsbury Laboratory Cambridge University (SLCU), UK

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Li et al., 2012)

SDN1
TALENs

Iowa State University, USA

Pospiviroids detection method. Pospiviroids are a major production constraint.
( Zhai et al., 2024 )

SDN1
CRISPR/Cas

Washington State University
USDA-ARS, USA

Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2019)

SDN1
CRISPR/Cas

Newe Ya’ar Research Center,
Agricultural Research Organization (ARO), Israel
University of California, USA

Viral resistance: increased resistance to infection with the potato virus Y (PVY) and tolerance to salt and osmotic stress. PVY is one of the most economically important potato pathogens
(Makhotenko et al., 2019)

SDN1
CRISPR/Cas

Russia Moscow State University, Russia
Doka Gene Technologies Ltd, USA

Viral resistance: increased resistance to turnip mosaic virus (TuMV).
(Lee et al., 2023)

SDN1
CRISPR/Cas

Rural Development Administration
Advanced Institute for Science and Technology, South Korea
North Carolina State University, USA

Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands

Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Viral resistance: reduced cassava brown streak disease (CBSD) symptom severity and incidence. CBSD threatens cassava production in West Africa and is a major constraint on cassava production in East and Central Africa.
(Gomez et al., 2019)

SDN1
CRISPR/Cas

University of California
Donald Danforth Plant Science Center, USA

Viral resistance: enhanced Potato virus Y (PVY) resistance. PVY infection can result in up to 70% yield loss globally.
(Le et al., 2022)

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology, Vietnam
University of Edinburgh, UK

Traits related to improved food/feed quality

Improved seed protein content.
( Shen et al., 2022 )

SDN1
CRISPR/Cas

Corteva Agriscience
University of Arizona, USA

Increased amylose content. Cereals high in amylose content (AC) and resistant starch (RS) offer potential health benefits and reduce risks of diseases such as coronary heart disease, diabetes and certain colon and rectum cancers.
( Sun et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA
University of Liege, Belgium

Increased digestibility and protein quality. Reduced kafirin levels. Kafirins are the major storage proteins in sorghum grains and form protein bodies with poor digestibility. Kafirins are devoid of the essential amino acid lysine, they also impart poor protein quality to the kernel.
( Li et al., 2018 )

SDN1
CRISPR/Cas

University of Nebraska
University of Missouri, USA

β-conglycinin deficiency, which lowers allergenicity and increases nutritional value.
( Song et al., 2024 )

SDN1
CRISPR/Cas

Northeast Agricultural University/Key Laboratory of Soybean Biology of the Chinese Education Ministry
Harbin Normal University
Keshan Branch of Heilongjiang Academy of Agricultural Sciences
Jilin Agricultural University, China
USDA Agricultural Research Service
University of Missouri, USA

Promoted phenolic acid biosynthesis. Salvia is tradional Chinese medicine with great medical value to treat cardio- and cerebrovascular diseases. Phenolic acids make up a big part of the bioactive compounds.
( Shi et al., 2021 )

SDN1
CRISPR/Cas

East China University of Science and Technology
Zhejiang Chinese Medical University, China
University of Hawaii at Manoa, USA

Glossy phenotype. Reduced epicuticular wax in leaves.
( Char et al., 2015 )

SDN1
TALENs

Iowa State University, USA

Carotenoid-enriched. Carotenoids, the source of pro vitamin A, are an essential component of dietary antioxidants.
( Dong et al., 2020 )

SDN3
CRISPR/Cas

University of California
Innovative Genomics Institute
The Joint Bioenergy Institute, USA

Enhanced oil composition. Increased oleic acid content and significant decreases in the less desirable polyunsaturated fatty acids, linoleic acid (i.e. a decrease from ~16% to <4%) and linolenic acid (a decrease from ~35% to <10%).
( Jiang et al., 2016 )

SDN1
CRISPR/Cas

University of Nebraska
University of California, USA

High oleic and low linolenic oil to improve nutritional characteristics, increase shelf-life and frying stability.
( Demorest et al., 2016 )

SDN1
TALENs

Cellectis plant science Inc.
Calyxt, USA

Amylose-free starch in tubers.
( Toinga-Villafuerte et al., 2022 )

SDN1
CRISPR/Cas

Texas A&
M University, USA

Improve glutinosity in elite varieties. Decreased amylose content without affecting other desirable agronomic traits.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University
University of Queensland, USA

Attenuated toxic cyanogen production. Cassava produces toxic cyanogenic compounds and requires food processing for safe consumption.
( Gomez et al., 2021 )

SDN1
CRISPR/Cas

University of California
Donald Danforth Plant Science Center
Lawrence Berkeley National Laboratory
Okinawa Institute of Science and Technology Graduate University
Chan-Zuckerberg BioHub, USA

High-quality sugar production by rice (98% sucrose content). Carbohydrates are an essential energy-source. Sugarcane and sugar beet were the only two crop plants used to produce sugar.
( Honma et al., 2020 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University, China
Faculty of Engineering
Kitami Institute of Technology
NagoyaUniversity
Tokyo Metropolitan University, Japan
Carnegie Institution for Science, USA

High levels of beta-carotene accumulation.
( Lu et al., 2006 )

SDN1
CRISPR/Cas

Cornell University
University of Minnesota, USA

Increased RS. Cereals high in RS may be beneficial to improve human health and reduce the risk of diet-related chronic diseases.
( Biswas et al., 2022 )

SDN1
CRISPR/Cas

Texas A&
M Univ.
Avance Biosciences Inc., USA

Increased lysine content with recovered kernel hardness. Lysine is considered of great nutritional importance in animal feeds and human foods.
( Hurst et al., 2023 )

SDN1
CRISPR/Cas

University of Nebraska-Lincoln
Center for Plant Science Innovation
University of Missouri-Columbia, USA

Enhancing the accumulation of eicosapentaenoic acid and docosahexaenoic acid, essential components of a healthy, balanced diet.
( Han et al., 2022 )

SDN1
CRISPR/Cas

Rothamsted Research, UK
Montana State University, USA

Low polyunsaturated fats content. Soybean oil is high in polyunsaturated fats and is often partially hydrogenated. The trans-fatty acids produced through hydrogenation pose a health threat.
( Haun et al., 2014 )

SDN1
TALENs

Cellectis plant sciences Inc., USA

Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )

SDN1
CRISPR/Cas

University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France

High-oleic acid content. Oleic acid has increased oxidative stability compared to linolenic and linoleic acid, improving fuel stability and the oil's suitability for high-temperature food applications, for example frying.
( Jarvis et al., 2021 )

SDN1
CRISPR/Cas

Illinois State University
University of North Texas
University of Nebraska-Lincoln, USA

Reduced grain chalkiness.
( Gann et al., 2023 )

SDN1
CRISPR/Cas

Cell and Molecular Biology Program
Department of Chemistry and Biochemistry
University of Arkansas at Little Rock, USA

Improved starch quality. Reduced amylopectin and increased amylose percentage.
( Wang et al., 2019 )

SDN1
CRISPR/Cas

Shanghai Institutes for Biological Sciences
Shanghai Sanshu Biotechnology Co. LTD
Chinese Academy of Science, China
University of Kentucky, USA

Increased iron content in potato plants. Iron is an essential micronutrient.
( Chauhan et al., 2024 )

SDN1
CRISPR/Cas

Panjab University
Panjab University
National Institute of Plant Genome Research, India
University of Minnesota, USA

Decreases in palmitic acid, increased total C18 and reduced total saturated fatty acid contents. Reduced saturated fat content is connected to lowered cardiovascular disease rate.
( Gupta et al., 2012 )

SDN1
ZFN

Dow AgroSciences
Sangamo BioSciences, USA

Increased grain number per spikelet.
( Zhang et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK

Modified composition: accumulation of fivefold more starch than WT leaves, and more sucrose as well. Architectural changes
(Bezrutczyk et al., 2018)

SDN1
CRISPR/Cas

Heinrich Heine University Düsseldorf
Max Planck Institute for Plant Breeding Research, Germany
Department of Plant Biology, Carnegie Science, USA

Large parthenocarpic fruits. Parthenocarpy, also known as seedless fruits, is preferred by consumers and it ensures consistent fruit yield in variable environmental conditions.
( Hu et al., 2023 )

SDN1
CRISPR/Cas

Duke University, USA

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Reduced raffinose family oligosaccharide (RFO) levels in seeds. Human and other monogastric animals cannot digest major soluble carbohydrates, RFOs.
( Le et al., 2020 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology, Vietnam
University of Missouri, USA
Leibniz Institute of Plant Genetics and Crop Plant Research
Germany

Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy

Reduced phytate production + herbicide tolerance. Generation of a dual phenotype through targeted manipulation of a single locus.
( Shukla et al., 2009 )

SDN3
ZFN

Dow AgroScience, USA

Reduced content of trypsin inhibitors, one of the most abundant anti-nutritional factors in soybean seeds. Reduction of trypsin inhibitors leads to improved. digestibility of soybean meal.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Virginia Tech, USA

Increased sucrose content.
( Ren et al., 2020 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement
Capital Normal University
China Agricultural University, China
Cornell University
Robert W. Holley Center for Agriculture and Health, USA

Lower oil content and altered fatty acid composition. Most commercially produced oil seeds synthesize only a relatively small range of fatty acids, offering limited functionality.
( Aznar-Moreno et al., 2017 )

SDN1
CRISPR/Cas

Kansas State University, USA

Reduced gluten content. Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins.
( Sánchez-León,et al., 2017 )

SDN1
CRISPR/Cas

Instituto de Agricultura Sostenible (IASCSIC), Spain
University of Minnesota, USA

Ultra-low nicotine level
( Burner et al., 2022 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Increased sugar and amino acid content leading to improved fruit quality.
( Nguyen et al., 2023 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology
Food Industries Research Institute, Vietnam
University of Missouri, USA

Altered lignin composition: decreased syringyl monolignol / guaiacylmonolignol (S/G) ratio. The monolignol ratio has been proposed to affect biomass recalcitrance and the resistance to plant disease.
(Cao et al., 2021)

SDN1
CRISPR/Cas

SouthwestUniversity, China
University of Wisconsin, USA

High oleic, low linoleic and alpha-linolenic acid phenotype. High concentration of linoleic and alpha-linolenic acids causes oxidative instability.
( Do et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri, USA
Vietnam Academy of Science and Technology, Vietnam

Mutant cell lines doubled the accumulation level of anthocyanins biosynthesized. The production of these important pigments was stabilized over time.
( D'Amelia et al., 2022 )

SDN1
CRISPR/Cas

National Research Council of Italy
University of Naples Federico II
Council for Agricultural Research and Economics, Italy

Alteration of the inositol phosphate profile in developing seeds.
( Shukla et al., 2009 )

SDN1
ZFN

Dow AgroSciences
Sangamo BioSciences, USA

High fruit malate accumulation. Malate is a primary organic acid in tomato and a crucial compound that contributes to fruit flavor and palatability.
( Ye et al., 2017 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
Cornell University, USA

Increased levels of oleic acid and alpha-linolenic acid. Camelina is a low-input oilseed crop. It is necessary to ameloriate fatty acid composition in oils to meet different application requirements.
( Ozseyhan et al., 2018 )

SDN1
CRISPR/Cas

Montana State University, USA

Improvement of starch quality.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Science

Shanghai Sanshu Biotechnology Co.
LTD, China
University of Kentucky, USA

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to improved food/feed quality