genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 34 results

Traits related to biotic stress tolerance

Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Bacterial resistance: resistance against bacterial spot disease, caused by Xanthomonas species, which could be a devastating to tomato as well as pepper.
(Ortega et al., 2024)

SDN1
CRISPR/Cas

University of California
University of Florida, USA

Mutants were compromised in infectivity of Phytophthora palmivora, a destructive oomycete plant pathogen with a wide host range
( Pettongkhao et al., 2022 )

SDN1
CRISPR/Cas

Prince of Songkla University, Thailand
University of Hawaii at Manoa
East-West Center, USA
Sainsbury Laboratory Cambridge University (SLCU), UK

Fungal resistance: improved resistance to necrotrophic fungus Botrytis cinerea.
(Jeon et al., 2020)

SDN1
CRISPR/Cas

Stanford University, UK
L’Oreal, France
Howard Hughes Medical Institute, USA

Pospiviroids detection method. Pospiviroids are a major production constraint.
( Zhai et al., 2024 )

SDN1
CRISPR/Cas

Washington State University
USDA-ARS, USA

Fungal resistance: Reduced pathogenicity to the oomycete Phytophthora palmivora, a destructive pathogen that infects all parts of papaya plants. Increased papain sensitvity of in-vitro growth. Papaya fruits contain papain, a cysteine protease that mediates plant defense against pathogens and insects.
(Gumtow et al., 2018)

SDN1
CRISPR/Cas

University of Hawaii at Manoa, USA

Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2019)

SDN1
CRISPR/Cas

Newe Ya’ar Research Center,
Agricultural Research Organization (ARO), Israel
University of California, USA

Effective detection of a resistance-breaking strain of tomato spotted wilt virus (TSWV). TSWV causes a great threat to various food crops globally and can cause devastating epidemics.
( Shymanovich et al., 2024 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Bacterial resistance: resistance to different pathogens including Xanthomonas spp., P. syringae and P. capsici.
(de Toledo Thomazella et al., 2016)

SDN1
CRISPR/Cas

University of California, USA

Traits related to abiotic stress tolerance

Modulate aluminium resistance. Aluminum (Al) toxicity is the main factor inhibiting plant root development and reducing crops yield in acidic soils.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Academy of Agricultural and Forestry Sciences
China Agricultural University, China
University of California, USA

Traits related to improved food/feed quality

High fruit malate accumulation. Malate is a primary organic acid in tomato and a crucial compound that contributes to fruit flavor and palatability.
( Ye et al., 2017 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
Cornell University, USA

Large parthenocarpic fruits. Parthenocarpy, also known as seedless fruits, is preferred by consumers and it ensures consistent fruit yield in variable environmental conditions.
( Hu et al., 2023 )

SDN1
CRISPR/Cas

Duke University, USA

Increased sugar and amino acid content leading to improved fruit quality.
( Nguyen et al., 2023 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology
Food Industries Research Institute, Vietnam
University of Missouri, USA

Traits related to increased plant yield and growth

Shortened plant architecture and jointless pedicel without affecting the yield. This plant architecture can allow ground cultivation systems that do not require the support of stakes and ties and could be ultimately suitable for once-over mechanical harvesting.
( Lee et al., 2022 )

SDN1
CRISPR/Cas

University of Florida, USA

Plant development. Phenotypes consistent with increased GA response: tall and slender with light green vegetation.
(Lor et al., 2014)

SDN1
TALENs

University of Minnesota, USA
Hebrew University of Jerusalem, Israel

Dwarf phenotype. Tomatoes with compact growth habits and reduced plant height can be useful in some environments.
( Tomlinson et al., 2019 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
University of Minnesota, USA

Early flowering. Day-light sensitivity limited the geographical range of cultivation.
( Soyk et al., 2016 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory, USA
Max Planck Institute for Plant Breeding Research, Germany
Université Paris-Scalay, France

Customize tomato cultivars for urban agriculture: increased compactness and decreased growth cycle of tomato plants.
(Kwon et al., 2020)

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
Cornell University
University of Florida, USA
Wonkwang University, South Korea
Weizmann Institute of Science, Israel

Bigger seedlings.
( Lor et al., 2014 )

SDN1
TALENs

University of Minnesota, USA

Combine agronomically desirable traits with useful traits present in wild lines. Threefold increase in fruit size and a tenfold increase in fruit number. Fruit lycopene accumulation is improved by 500% compared with the widely cultivated S. lycopersicum.
( Zsögön et al., 2018 )

SDN1
CRISPR/Cas

Universidade Federal de Viçosa
Universidade de São Paulo Paulo, Brazil
University of Minnesota, USA
Universität Münster, Germany

Increased fruit size. Highly branched inflorescence and formation of multiple flowers.
( Rodriguez-Leal et al., 2017 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
University of Massachusetts Amherst, USA

Increase in floral organ number or fruit size, conferring enhanced tomato fruit yield.
( Rodriguez-Leal et al., 2017 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
University of Massachusetts Amherst, USA

Traits related to industrial utilization

Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )

SDN1
CRISPR/Cas

University of California
Emory University, USA
University of Cambridge, UK

Accelerated abscission. Plant organ abscission is a process important for development and reproductive success,
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Key Laboratory of Protected Horticulture of Ministry of Education, China
University of California at Davis
Crops Pathology and Genetic Research Unit, USA

Traits related to herbicide tolerance

Chlorsulfuron resistance.
( Huang et al., 2023 )

University of Florida, USA

Traits related to product color/flavour

Colour modification. Purple tomatoes.
( Cermak et al., 2015 )

SDN2
TALENs

University of Minnesota, USA
Academy of Sciences of the Czech Republic, Czech Republic

Increased content of phenylacetaldehyde, sucrose and fructose, which are major contributors to flavor in many foods, including tomato.
( Li et al., 2023 )

SDN1
CRISPR/Cas

University of Florida, USA
Max-Planck-Institute of Molecular Plant Physiology, Germany

Colour modification. Purple tomatoes.
( Cermak et al., 2015 )

SDN2
CRISPR/Cas

University of Minnesota, USA
Academy of Sciences of the Czech Republic, Czech Republic

Albino phenotype.
( Brewer et al., 2022 )

SDN1
CRISPR/Cas

University of Florida, USA

Traits related to storage performance

Improved shelf-life with improved or not affected sugar: acid ratio, aroma volatiles, and skin color.
(Ortega-Salazar et al., 2023)

SDN1
CRISPR/Cas

University of California, USA
Zhejiang Normal University, China
University of Nottingham, UK

Delayed fruit ripening.
( Lang et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University, USA

Improved shelf-life by targeting the genes modulating pectin degradation in ripening tomato.
( Wang et al., 2019 )

SDN1
CRISPR/Cas

University of London
University of Leicester
University of Nottingham
University of Leeds, UK
International Islamic University Malaysia, Malaysia
Shanxi Academy of Agricultural Sciences, China
University of California, USA

Controlling the rate of fruit softening to extend shelf life.
( Uluisik et al., 2016 )

SDN1
CRISPR/Cas

University of Nottingham
Royal Holloway University of London
Heygates Ltd
Syngenta Seeds
Sutton Bonington Campus, UK
Syngenta Crop Protection
University of California
Cornell University
Skidmore College, USA

Delayed fruit ripening.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Nanjing Agricultural University, China
University of Connecticut, USA

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour

Traits related to storage performance