genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 38 results

Traits related to biotic stress tolerance

Viral resistance: reduced viral accumulation and amelioration of virus-induced symptoms by Potato Virus Y.
(Lucioli et al., 2022)

SDN1
CRISPR/Cas

ENEA
Council for Agricultural Research and Economics (CREA), Italy
National Agricultural Research and Innovation Centre, Hungary

Viral resistance: to Cotton Leaf Curl Kokhran Virus, causing Cotton leaf curl disease (CLCuD), a very devastating and prevalent disease. CLCuD causes huge losses to the textile and other industries.
(Hamza et al., 2021)

SDN1
CRISPR/Cas

National Institute for Biotechnology and Genetic Engineering, Pakistan

Broad-spectrum resistance against multiple Potato virus Y (PVY)-strains.
( Noureen et al., 2022 )

SDN1
CRISPR/Cas

Constituent College of Pakistan Institute of Engineering and Applied Sciences (PIEAS)
University Institute of Biochemistry and Biotechnology (UIBB), Pakistan

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Xu et al., 2021)

SDN1
TALENs

Shanghai Jiao Tong University, China
Crop Diseases Research Institute, Pakistan

Viral resistance: reduced cotton leaf curl viral (CLCuV) load with asymptomatic plants. <br /> CLCuV causes a very devastating and prevalent disease. It causes huge losses to textile and other industries.
(Shakoor et al., 2023)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Pacific Biosciences
CureVac Manufacturing GmbH, Germany

Fungal resistance: Enhanced resistance to powdery mildew, a fungal disease causing great losses in soybean yield and seed quality.
(Bui et al., 2023)

SDN1
CRISPR/Cas

Institute of Biotechnology
University of Science and Technology of Hanoi
Vietnam Academy of Science and Technology
Vietnam Academy of Agriculture Science, Vietnam
Washington University in St. Louis
University of Missouri, USA

Bacterial resistance: resistance against banana Xanthomonas wilt (BXW) disease, caused by Xanthomonas campestris pv. musacearum. BXW forms a great threat to banana cultivation in East and Central Africa.
(Ntui et al., 2023)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture, Kenya

Viral resistance: increased control on viral pathogen Banana streak virus (BSV). The BSV integrates in the banana host genome as endogenous BSV (eBSV). When banana plants are stressed, the eBSV produces infectious viral particles and thus the plant develops disease symptoms.
(Tripathi et al., 2019)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya
University of California, USA

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zafar et al., 2020)

SDN1
CRISPR/Cas

Constituent College of Pakistan Institute of Engineering and Applied Sciences
University of Information Technology
Engineering and Management Sciences
Constituent College of Pakistan Institute of Engineering and Applied Sciences, Pakistan

Viral resistance: increased resistance to chickpea chlorotic dwarf virus (CpCDV).
(Malik et al., 2023)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Viral resistance: enhanced Potato virus Y (PVY) resistance. PVY infection can result in up to 70% yield loss globally.
(Le et al., 2022)

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology, Vietnam
University of Edinburgh, UK

Bacterial resistance: Enhanced resistance to Xanthomonas campestris pv. musacearum, causing Bananas Xanthomonas wilt (BXW). Overall economic losses caused by Xanthomonas campestris were estimated at 2-8 billion USD over a decade.
(Tripathi et al., 2021)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya

Fungal resistance: Increased tolerance against Fusarium oxysporum f. sp. lycopersici, causing vascular wilt.
(Ijaz et al., 2022)

SDN1
CRISPR/Cas

University of Agriculture, Pakistan

Resistance to parasitic weed: Striga spp. The parasitic plant reduces yields of cereal crops worldwide.
(Hao et al., 2023)

SDN1
CRISPR/Cas

University of Nebraska-Lincoln
Pennsylvania State University, USA
International Maize and Wheat Improvement Center (CIMMYT), Senegal
Kenyatta University, Kenya

Viral resistance: Highly efficient resistance against wheat dwarf virus (WDV), an economically important virus. WDV infect both wheat and barley causing severe yield losses. The natural resistance resources are limited.
(Kis et al., 2019)

SDN1
CRISPR/Cas

University of Pannonia
Hungarian Academy of Sciences
Eötvös Loránd University University
Szent István University, Hungary

Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Traits related to abiotic stress tolerance

Enhanced salt tolerance.
( Ly et al., 2024 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology
Agricultural Genetics Institute, Vietnam

Drought tolerance.
( Njuguna et al., 2018 )

SDN1
CRISPR/Cas

Ghent University
Center for Plant Systems Biology, Belgium
Jomo Kenyatta University of Agriculture and Technology, Kenya

Higher tolerance to salt and osmotic stress through reduced stomatal conductance coupled with increased leaf relative water content and Abscisic acid (ABA) content under normal and stressful conditions.
( Bouzroud et al., 2020 )

SDN1
CRISPR/Cas

Université Mohammed V de Rabat, Morocco
Université de Toulouse, France
Universidade Federal de Viçosa, Brazil

Tolerance to salt stress.
( Tran et al., 2021 )

SDN1
CRISPR/Cas

Gyeongsang National University, South Korea
College of Agriculture
Bac Lieu University, Vietnam

Traits related to improved food/feed quality

High oleic, low linoleic and alpha-linolenic acid phenotype. High concentration of linoleic and alpha-linolenic acids causes oxidative instability.
( Do et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri, USA
Vietnam Academy of Science and Technology, Vietnam

Reduce malnutrition by decreasing antinutrient phytic acid (PA) and increasing Iron and Zinc accumulation. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Ibrahim et al., 2021 )

SDN1
CRISPR/Cas

Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan

Increased sugar and amino acid content leading to improved fruit quality.
( Nguyen et al., 2023 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology
Food Industries Research Institute, Vietnam
University of Missouri, USA

Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )

SDN1
CRISPR/Cas

Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan

Improved cold storage and processing traits: lower levels of reduced sugars
(Yasmeen et al., 2022)

SDN1
CRISPR/Cas

University of the Punjab, Pakistan

Reduced raffinose family oligosaccharide (RFO) levels in seeds. Human and other monogastric animals cannot digest major soluble carbohydrates, RFOs.
( Le et al., 2020 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology, Vietnam
University of Missouri, USA
Leibniz Institute of Plant Genetics and Crop Plant Research
Germany

Traits related to increased plant yield and growth

Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )

SDN1
CRISPR/Cas

Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea

Increase in 1000-grain weight, grain area, grain width, grain length, plant height, and spikelets per spike.
( Errum et al., 2023 )

SDN1
CRISPR/Cas

National Agricultural Research Centre (NARC)
PARC Institute of Advanced Studies in Agriculture (PIASA)
Pakistan Agricultural Research Council, Pakistan

Altered plant architecture to inrease yield: increased node number on the main stem and branch number.
(Bao et al., 2019)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
Duy Tan University, Vietnam
RIKEN Center for Sustainable Resource Science, Japan

Increased tiller number.
( Awan et al., 2024 )

SDN1
CRISPR/Cas

National Institute for Biotechnology and Genetic Engineering
Quaid-i-Azam University, Pakistan

Traits related to industrial utilization

Early heading: in regions with short growing seasons, early maturing varieties to escape frost damage are required.
(Sohail et al., 2022)

SDN1
CRISPR/Cas

China National Rice Research Institute
Northern Center of China National Rice Research Institute
Zhejiang A&
F University, China
Mir Chakar Khan Rind University
Agriculture Research System Khyber, Pakistan
Ministry of Agriculture, Bangladesh
Agriculture Research Center, Egypt

Conferring water logging tolerance for further expansion of the cultivation area.
( Abdullah et al., 2021 )

SDN1
CRISPR/Cas

Faculty of Agriculture
University of Nottingham
Universiti Putra Malaysia, Malaysia

Traits related to herbicide tolerance

Herbicide tolerance: Bispyribac-sodium (BS). BS is a pyrimidinyl carboxy herbicide.
(Zafar et al., 2023)

SDN2
CRISPR/Cas

Constituent College of Pakistan Institute of Engineering and Applied Sciences
Engineering and Management Sciences (BUITEMS), Pakistan

Traits related to product color/flavour

Albino phenotype.
( Syombua et al., 2021 )

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA)
University of Nairobi, Kenya
University of Missouri
Iowa State University
Donald Danforth Plant Science Center, USA

Albino phenotype.
( Yeap et al., 2021 )

SDN1
CRISPR/Cas

Sime Darby Plantation Technology Centre Sdn. Bhd.
Sime Darby Plantation Research Sdn. Bhd., Malaysia

Albino phenotype
( Bánfalvi et al., 2020 )

SDN1
CRISPR/Cas

NARIC Agricultural Biotechnology Institute, Hungary

Traits related to storage performance

Extended root shelf-life, which decreases its wastage.
( Mukami et al., 2023 )

SDN1
CRISPR/Cas

Kenyatta University
Jomo Kenyatta University of Agriculture Technology
Pwani University Kilifi, Kenya

Improved shelf-life by targeting the genes modulating pectin degradation in ripening tomato.
( Wang et al., 2019 )

SDN1
CRISPR/Cas

University of London
University of Leicester
University of Nottingham
University of Leeds, UK
International Islamic University Malaysia, Malaysia
Shanxi Academy of Agricultural Sciences, China
University of California, USA

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour

Traits related to storage performance