genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 51 results

Traits related to biotic stress tolerance

Viral resistance: Increased resistance to the barley mild mosaic virus (BaMMV), which can cause yield losses as high as 50% upon infection.
(Hoffie et al., 2022)

SDN1
CRISPR/Cas

Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK)
Federal Research Centre for Cultivated Plants, Germany

Fungal resistance: Reduced susceptibility to Verticillium longisporum, fungal pathogen that causes stem striping in Brassica napus and leads to huge yield losses.
(Ye et al., 2024)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
Hohenlieth-Hof, NPZ Innovation GmbH, Germany
Aswan University, Egypt
Fujian Agriculture and Forestry University, China

Fungal resistance: resistance to Oidium neolycopersici, causing powdery mildew.
(Nekrasov et al., 2017)

SDN1
CRISPR/Cas

Max Planck Institute for Developmental Biology, Germany
Norwich Research Park, UK

Bacterial resistance: improved resistance to Xanthomonas oryzae, which causes bacterial blight, a devastating rice disease resulting in yield losses.
(Oliva et al., 2019)

SDN1
CRISPR/Cas

International Rice Research Institute, Philippines
University of Missouri
University of Florida
Iowa State University
Donald Danforth Plant Science Center, USA
Université Montpellier, France
Heinrich Heine Universität Düsseldorf
Max Planck Institute for Plant Breeding Research
Erfurt University of Applied Sciences, Germany
Nagoya University, Japan

Fungal resistance: enhanced resistance against rust caused by Puccinia striiformis f. sp. tritici and powdery mildew caused by Blumeria graminis f. sp. tritici., while also increasing yield.
(Liu et al., 2024)

SDN1
CRISPR/Cas

Southwest University
Yangtze University, China
University of Cologne, Germany
University of Maryland

Fungal resistance: reduced susceptibility to Verticillium longisporum, a pathogen causing Verticillium stem striping. No fungicide treatments are currently available to control this disease.
(Pröbsting et al., 2020)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
NPZ Innovation GmbH, Germany

Fungal resistance: increased resistance to both biotrophic and necrotrophic plant pathogenic fungi, Bipolaris spot blotch and Fusarium root rot.
(Galli et al., 2022)

SDN1
CRISPR/Cas

Justus Liebig University, Germany

Viral resistance: enhanced resistance against wheat dwarf virus, which is a causal agent of wheat viral disease and can significantly impact wheat production worldwide.
(Yuan et al., 2024)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Northwest A&
F University, China

Norwegian Institute of Bioeconomy Research, Norway

Viral resistance: reduced cotton leaf curl viral (CLCuV) load with asymptomatic plants. <br /> CLCuV causes a very devastating and prevalent disease. It causes huge losses to textile and other industries.
(Shakoor et al., 2023)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Pacific Biosciences
CureVac Manufacturing GmbH, Germany

Viral resistance: Resistance to Potato Virus Y (PVY), one of the most devastating viral pathogens causing substantial harvest losses.
(Zhan et al., 2019)

CRISPR/Cas

Hubei University
Huazhong Agricultural University, China
Max‐Planck‐Institut für Molekulare Pflanzenphysiologie, Germany

Viral resistance: improved resistance to yellow leaf curl virus (TYLCV).
(Tashkandi et al., 2018)

SDN1
CRISPR/Cas

Princess Nourah bint Abdulrahman University
4700 King Abdullah University of Science and Technology, Saudi Arabia

Detection method for the geminiviruses, tomato yellow leaf curl virus and tomato leaf curl New Delhi virus, which can cause huge economic losses and pose a threat to sustainable agriculture.
( Mahas et al., 2021 )

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology (KAUST), Saudi Arabia

Viral resistance: resistance to rice tungro spherical virus, causing rice tungro disease (RTD). RTD is a serious threat for rice production in tropical Asia.
(Macovei et al., 2018)

SDN1
CRISPR/Cas

International Rice Research Institute (IRRI), Philippines

Fungal resistance: decreased susceptibility to Ustilago maydis, causing smut. The pathogen causes galls on all aerial parts of the plant, impacting crop yield and quality.
(Pathi et al., 2020)

SDN1
CRISPR/Cas

Leibniz Institute of Plant Genetics and Crop Plant Research, Germany

Viral resistance: resistance to Tomato yellow leaf curl virus (TYLCV). Delayed or reduced accumulation of viral DNA and abolished or attenuated symptoms of infection.
(Ali et al., 2015)

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia

Fungal resistance: improved sheath blight resistance. Sheath blight disease caused by Rhizoctonia solani AGI-1A and is one of the three major rice diseases. Sheath blight disease can cause severe yield losses.
(Cao et al., 2021)

SDN1
CRISPR/Cas

Agricultural College of Yangzhou University
Jiangsu Yanjiang Institute of Agricultural Science
Yangzhou University
Testing Center of Yangzhou University
Ministry of Agriculture
Chinese Academy of Agricultural Sciences
Institutes of Agricultural Science and Technology Development, China
BASF, Germany

Traits related to abiotic stress tolerance

Improved salt stress resistance. Significant increase in the shoot weight, the total chlorophyll content, and the chlorophyll fluorescence under salt stress. Also high antioxidant activities coincided with less reactive oxygen species (ROS).
( Shah Alam et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University, China
Taif University, Saudi Arabia
Alexandria University, Egypt

Higher tolerance to salt and osmotic stress through reduced stomatal conductance coupled with increased leaf relative water content and Abscisic acid (ABA) content under normal and stressful conditions.
( Bouzroud et al., 2020 )

SDN1
CRISPR/Cas

Université Mohammed V de Rabat, Morocco
Université de Toulouse, France
Universidade Federal de Viçosa, Brazil

Traits related to improved food/feed quality

Increased amylose content in the seeds, thus a lower Glycemic Index (GI) value. Low GI rice is preferred to avoid a sudden rise in glucose in the bloodstream. Starch with a high GI threatens healthy individuals to get diabetes type II and proves extremely harmful for existing diabetes type II patients.
( Jameel et al., 2022 )

SDN1
CRISPR/Cas

Jamia Millia Islamia
International Centre for Genetic Engineering and Biotechnology, India
King Saud University, Saudi Arabia

Important metabolic changes affecting tomato fruit quality. Reduced contents of the anti-nutrient oxalic acid.
( Gago et al., 2017 )

SDN1
ZFN

University of Algarve, Portugal
Centre for Research and Technology Hellas
Technological Educational Institution of Crete, Greece

Glossy sheat phenotype.
( Gerasimova et al., 2023 )

SDN1
CRISPR/Cas

Siberian Branch of the Russian Academy of Sciences
Vavilov Institute of Plant Genetic Resources (VIR)
Siberian Branch of the Russian Academy of Sciences, Russia

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Germany

Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Sashidhar et al., 2020 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Max-Planck-Institute for Evolutionary Biology, Germany

Removing the major allergen to tackle food allergies.
( Assou et al., 2021 )

SDN1
CRISPR/Cas

Leibniz Universität Hannover
Technische Universität Braunschweig, Germany

Reduced glucosinolate levels. Glucosinolates are anti-nutrients that can cause reduced performance and impairment of kidney and liver functions of livestock.
( Hölzl et al., 2022 )

SDN1
CRISPR/Cas

University of Bonn
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Modified composition: accumulation of fivefold more starch than WT leaves, and more sucrose as well. Architectural changes
(Bezrutczyk et al., 2018)

SDN1
CRISPR/Cas

Heinrich Heine University Düsseldorf
Max Planck Institute for Plant Breeding Research, Germany
Department of Plant Biology, Carnegie Science, USA

Traits related to increased plant yield and growth

Improved spikelet number per panicle led to increased grain yield per plant.
( Ludwig et al., 2023 )

SDN1
CRISPR/Cas

International Rice Research Institute (IRRI), Philippines
University of Pavia, Italy

Control grain size and seed coat color.
( Tra et al., 2021 )

International Rice Research Institute, Philippines
Dahlem Center of Plant Sciences Freie UniversitÃ¤t, Germany
Synthetic Biology, Biofuel and Genome Editing R&
D Reliance Industries Ltd, India

Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )

SDN1
CRISPR/Cas

Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea

Increased water use efficiency, a promising approach for achieving sustainable crop production in changing climate scenarios.
( Blankenagel et al., 2022 )

SDN1
CRISPR/Cas

Technical University of Munich
Max Planck Institute of Molecular Plant Physiology
Helmholtz Center Munich
Heinrich Heine University Düsseldorf, Germany

Induced erect leaf habit and shoot growth for a more efficient light penetration into lower canopy layers.
( Fladung et al., 2021 )

SDN1
CRISPR/Cas

Thünen Institute of Forest Genetics, Germany

Increased grain yield without side effect.
( Gho et al., 2022 )

SDN1
CRISPR/Cas

Kyung Hee University, South Korea
International Rice Research Institute, Philippines

Increased shatter resistance to avoid seed loss during mechanical harvest.
( Braatz et al., 2017 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel, Germany

Increased yield: plants produced more tillers and grains than azygous wild-type controls and the total yield was increased up to 15 per cent.
(Holubova et al., 2018)

SDN1
CRISPR/Cas

Palacký University
Centre of the Region Haná for Biotechnological and Agricultural Research, Czech Republic
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Combine agronomically desirable traits with useful traits present in wild lines. Threefold increase in fruit size and a tenfold increase in fruit number. Fruit lycopene accumulation is improved by 500% compared with the widely cultivated S. lycopersicum.
( Zsögön et al., 2018 )

SDN1
CRISPR/Cas

Universidade Federal de Viçosa
Universidade de São Paulo Paulo, Brazil
University of Minnesota, USA
Universität Münster, Germany

Reduced seed dormancy: rapid and uniform germination of seeds is important for rice production. Mutant seeds began to germinate 1 day after sowing, while WT seeds needed 2 days.
(Jung et al., 2019)

SDN1
CRISPR/Cas

Hankyong National University
Chungbuk National University
Hanyang University, China
Central Luzon State University, Philippines

Increased seed oil content (SOC). SOC is a major determinant of yield and quality.
( Karunarathna et al., 2020 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel, Germany
Zhejiang University, China

Control meristem size to increase fruit yield.
( Yuste-Lisbona et al., 2020 )

SDN1
CRISPR/Cas

Universidad de Almería
Universitat Politècnica de València–Consejo Superior de Investigaciones Científicas
Spain
Max Planck Institute for Plant Breeding Research
Thünen Institute of Forest Genetics, Germany
Université Paris-Saclay, France

Increased water use efficiency without growth reductions in well-watered conditions.
( Blankenagel et al., 2022 )

SDN1
CRISPR/Cas

Technical University of Munich
Max Planck Institute of Molecular Plant Physiology
German Research Center for Environmental Health
KWS SAAT SE &
Co.KGaA
Université Technique de Munich
Heinrich Heine University, Germany
LEPSE - Écophysiologie des Plantes sous Stress environnementaux, France

Early flowering. Day-light sensitivity limited the geographical range of cultivation.
( Soyk et al., 2016 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory, USA
Max Planck Institute for Plant Breeding Research, Germany
Université Paris-Scalay, France

Increased grain yield and quality.
( Luo et al., 2024 )

SDN1
CRISPR/Cas

Guizhou University, China
King Saud University, Saudi Arabia

Altered spike architecture.
( de Souza Moraes et al., 2022 )

SDN1
CRISPR/Cas

Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany

Plant architecture: high tillering and reduced height.
(Butt et al., 2018)

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia

Root growth angle regulation, among the most important determinants of root system architecture. Root growth angle controls water uptake capacity, stress resilience, nutrient use efficiency and thus yield of crop plants.
( Kirschner et al., 2021 )

SDN1
CRISPR/Cas

University of Bonn
University of Cologne
Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben
Justus-Liebig-University Giessen, Germany
University of Bologna, Italy

Traits related to industrial utilization

Nicotine-free tobacco.
( Schachtsiek et al., 2019 )

SDN1
CRISPR/Cas

TU Dortmund University, Germany

Traits related to herbicide tolerance

Herboxidiene
( Butt et al., 2019 )

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology (KAUST), Saudi Arabia
Universite Paris-Saclay, France

Bispyribac sodium
( Butt et al., 2017 )

SDN2
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia
Agricultural Research Center, Egypt
Rice University, USA

Bispyribac sodium
( Butt et al., 2020 )

King Abdullah University of Science and Technology (KAUST), Saudi Arabia

Dinitroanaline
( Liu et al., 2021 )

Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University
Scientific Observing and Experimental Station of Crop Pests in Guilin, Ministry of Agriculture and Rural Affairs, China
Norwegian Institute of Bioeconomy Research, Norway

Bispyribac sodium
( Kuang et al., 2020 )

Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University, China
Norwegian Institute of Bioeconomy Research, Norway

Traits related to product color/flavour

Increased content of phenylacetaldehyde, sucrose and fructose, which are major contributors to flavor in many foods, including tomato.
( Li et al., 2023 )

SDN1
CRISPR/Cas

University of Florida, USA
Max-Planck-Institute of Molecular Plant Physiology, Germany

Colour shift. The poinsettia belongs to most economically important potted ornamental plants. Customers are willing to pay higher prices for unusual varieties.
( Nitarska et al., 2021 )

SDN1
CRISPR/Cas

Technische Universität Wien, Austria
Klemm+Sohn GmbH &
Co
Leibniz Universität Hannover, Germany

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour