Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Displaying 39 results

Traits related to biotic stress tolerance

Highly significant reduction in susceptibility to fire blight, caused by the bacterium Erwinia amylovora. Apple is one of the most cultivated fruit crops throughout the temperate regions of the world.
( Pompili et al., 2020 )
SDN1
CRISPR/Cas
Università degli Studi di Udine
Fondazione Edmund Mach, Italy
Bacterial resistance: Increased resistance to Erwinia amylovora, causing fire blight disease that threatens the apple and a wide range of ornamental and commercial Rosaceae host plants.
(Malnoy et al., 2016)
SDN1
CRISPR/Cas
Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea
Viral resistance: resistance to rice tungro disease (RTD), the most important viral disease that limits rice production.
(Kumam et al., 2022)
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University
International Centre for Genetic Engineering and Biotechnology
ICAR-Indian Institute of Rice Research, India
Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)
SDN1
CRISPR/Cas
Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands
Fungal resistance: strong resistance against Fusarium oxysporum f. sp. lycopersici (Fol), which causes Fusarium Wilt Disease in tomato.
(Debbarma et al., 2023)
SDN1
CRISPR/Cas
CSIR-North East Institute of Science and Technology
Academy of Scientific and Innovative Research
Assam Agricultural University
Central Muga Eri Research and Training Institute
International Crop Research Institute for the Semi Arid Tropics, India
Bacterial resistance: Resistance/moderately resistance against Bacterial leaf blight (BLB), caused by Xanthomonas oryzae pv oryzae (Xoo). BLB is a major constraint in rice production.
(Arulganesh et al., 2022)
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India
Oomycete resistance: resistance against downly mildew disease (DM). DM is caused by Peronospora belbahrii, a worldwide threat to the basil industry.
(Laura et al., 2023)
SDN1
CRISPR/Cas
Research Centre for Vegetable and Ornamental Crops
Institute of Agricultural Biology and Biotechnology
Institute for Sustainable Plant Protection
Research Centre for Olive Fruit and Citrus Crops
University of Pisa
Center for Agricultural Experimentation and Assistance
Institute of Biosciences and Bioresources, Italy
Viral resistance: reduced viral accumulation and amelioration of virus-induced symptoms by Potato Virus Y.
(Lucioli et al., 2022)
SDN1
CRISPR/Cas
ENEA
Council for Agricultural Research and Economics (CREA), Italy
National Agricultural Research and Innovation Centre, Hungary
Fungal resistance: Resistance to pathogen Colletotrichum truncatum, causing anthracnose, a major disease accounting for significant pre- and post-harvest yield losses.
(Mishra et al., 2021)
SDN1
CRISPR/Cas
Centurion University of Technology and Management
Siksha O Anusandhan University
Rama Devi Women'
s University, India
Viral resistance: increased resistance against Tobacco Mosaic Virus (TMV).
(Jogam et al., 2023)
SDN1
CRISPR/Cas
Kakatiya University
Center of Innovative and Applied Bioprocessing (DBT-CIAB), India
University of Minnesota
East Carolina University, USA
Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)
SDN1
CRISPR/Cas
Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University
South Korea
Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2021)
SDN1
CRISPR/Cas
Central University of Punjab, India
Newe Ya’ar Research Center
Agricultural Research Organization (ARO), Israel
Bacterial resistance: Plant moderately resistant against a strain of the gram-negative bacterium, Xanthomonas oryzae pv. oryzae (Xoo). Xoo severely impacts rice productivity by causing bacterial leaf blight disease.
(Bhagya Sree et al., 2023)
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India

Traits related to abiotic stress tolerance

Drought and salt tolerance.
( Kumar et al., 2020 )
SDN1
CRISPR/Cas
ICAR-Indian Agricultural Research Institute
Bhartidasan University, India

Traits related to improved food/feed quality

Seeds low in glucosinolate content and other plant parts high in glucosinolate levels. Glucosinolates are anti-nutrients that can cause reduced performance and impairment of kidney and liver functions of livestock, they also play a role in plant defence.
( Mann et al., 2023 )
SDN1
CRISPR/Cas
National Institute of Plant Genome Research
University of Delhi South Campus, India
Mutant cell lines doubled the accumulation level of anthocyanins biosynthesized. The production of these important pigments was stabilized over time.
( D'Amelia et al., 2022 )
SDN1
CRISPR/Cas
National Research Council of Italy
University of Naples Federico II
Council for Agricultural Research and Economics, Italy
Increased amylose content in the seeds, thus a lower Glycemic Index (GI) value. Low GI rice is preferred to avoid a sudden rise in glucose in the bloodstream. Starch with a high GI threatens healthy individuals to get diabetes type II and proves extremely harmful for existing diabetes type II patients.
( Jameel et al., 2022 )
SDN1
CRISPR/Cas
Jamia Millia Islamia
International Centre for Genetic Engineering and Biotechnology, India
King Saud University, Saudi Arabia
Reduced levels of phytic acid (PA). PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Krishnan et al., 2023 )
SDN1
CRISPR/Cas
ICAR-Indian Agricultural Research Institute (IARI)
Bharathidasan University, India
Reduced nicotine levels.
Nicotine is an addictive compound leading to severe diseases.
( Singh et al., 2023 )
SDN1
CRISPR/Cas
CSIR-National Botanical Research Institute
Academy of Scientific and Innovative Research (AcSIR)
Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), India
Generation of beta-carotene-enriched banana fruits. Carotenoids, the source of pro vitamin A, are an essential component of dietary antioxidants. Low intakes and poor bioavailability of provitamine A from the vegetarian diet are considered the main reasons for the widespread prevalence of Vitamine A deficiency.
( Kaur et al., 2020 )
SDN1
CRISPR/Cas
Ministry of Science and Technology (Government of India)
Panjab University, India
Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )
SDN1
CRISPR/Cas
University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France
Improved aleurone layer with enhanced grain protein content. Improved grain nutritional quality by improved accumulation of essential dietary minerals (Fe, Zn, K, P, Ca) in the endosperm of rice grain. Improved root and shoot architecture.
( Achary et al., 2021 )
SDN1
CRISPR/Cas
International Centre for Genetic Engineering and Biotechnology, India
Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy
Fragrant rice. Introduction of aroma into any non-aromatic rice varieties.
( Ashokkumar et al., 2020 )
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India

Traits related to increased plant yield and growth

Control grain size and seed coat color.
( Tra et al., 2021 )

BE
International Rice Research Institute, Philippines
Dahlem Center of Plant Sciences Freie Universität, Germany
Synthetic Biology, Biofuel and Genome Editing R&
D Reliance Industries Ltd, India
Delayed onset of ripening.
( Nizampatnam et al., 2023 )
SDN1
CRISPR/Cas
University of Hyderabad
SRM University-AP, India
Confer shoot architectural changes for increased resource inputs to increase crop yield.
( Stanic et al., 2021 )
SDN1
CRISPR/Cas
University of Calgary, Canada
SRM Institute of Technology, India
Root growth angle regulation, among the most important determinants of root system architecture. Root growth angle controls water uptake capacity, stress resilience, nutrient use efficiency and thus yield of crop plants.
( Kirschner et al., 2021 )
SDN1
CRISPR/Cas
University of Bonn
University of Cologne
Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben
Justus-Liebig-University Giessen, Germany
University of Bologna, Italy

Increased stomatal density, stomatal conductance, photosynthetic rate and transpiration rate. Fine tuning the stomatal traits can enhance climate resilience in crops.
( Rathnasamy et al., 2023 )
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University
Sugarcane Breeding Institute, India
Improved spikelet number per panicle led to increased grain yield per plant.
( Ludwig et al., 2023 )
SDN1
CRISPR/Cas
International Rice Research Institute (IRRI), Philippines
University of Pavia, Italy

Traits related to industrial utilization

Haploid induction to accelerate breeding in crop plants.
( Rangari et al., 2023 )
SDN1
CRISPR/Cas
Punjab Agricultural University, India
Removal of methyl iodide emissions. The release of methyl iodide in the athmospere causes ozone depletion and thus represents an important environmental threat.
( Carlessi et al., 2021 )
SDN1
CRISPR/Cas
PlantLab
Institute of Life Sciences
Scuola Superiore Sant’Anna
University of Pisa
University of Milan, Italy
Genetic variability. The genetically reprogrammed rice plants can act as donor lines to stabilize important agronomic traits or can be a potential resource to create more segregating population.
( K et al., 2021 )
SDN1
CRISPR/Cas
University of Agricultural Sciences
Regional Centre for Biotechnology, India
Accelerated domestication of African rice landraces by improving domestication traits such as sheed shattering, lodging and seed yield. The acceleration of the development of high-yield African landrace varieties is important considering that Africa has a strong growing population and prone to food shortage.
( Lacchini et al., 2020 )
SDN1
CRISPR/Cas
University of Milan, Italy
University of Montpellier, France
Induction of haploid plants and a reduced seed set for rice breeding.
( Yao et al., 2018 )
SDN2
CRISPR/Cas
ZhongGuanCun Life Science Park, China
Syngenta India Limited
Technology Centre
Medchal Mandal, India
Syngenta Crop Protection
LLC
Research Triangle Park, USA

Traits related to product color/flavour

Albino phenotype.
( Kaur et al., 2017 )
SDN1
CRISPR/Cas
National Agri-Food Biotechnology Institute (NABI), India
Anthocyanin-rich and pigmented sweet oranges.
( Salonia et al., 2022 )
SDN1
CRISPR/Cas
Research Centre for Olive Fruit and Citrus Crops
University of Catania
Research and Innovation Centre Trento, Italy
Albino phenotype.
( Phad et al., 2023 )
SDN1
CRISPR/Cas
Plant Biotechnology Research Center, India

Traits related to storage performance

Reduced fruit flesh browning. The browning of eggplant berry flesh after cutting has a negative impact on fruit quality for both industrial transformation and fresh consumption.
( Maioli et al., 2020 )
SDN1
CRISPR/Cas
University of Torino, Italy
Instituto de Biologica Molecular y Celular de Plantas (IBMCP)
Universitat Politècnica de València, Spain