genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 42 results

Traits related to biotic stress tolerance

Viral resistance: resistance to potyvirus potato virus Y (PVY), which causes serious yield loss.
(Kumar et al., 2022)

SDN1
CRISPR/Cas

Agricultural Research Organization, Israel

High resistance to powdery mildew under semi-commercial growth conditions.
( Shnaider et al., 2022 )

SDN1
CRISPR/Cas

Agricultural Research Organization Volcani Center, Israel

Fungal resistance: Reduced susceptibility to Verticillium longisporum, fungal pathogen that causes stem striping in Brassica napus and leads to huge yield losses.
(Ye et al., 2024)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
Hohenlieth-Hof, NPZ Innovation GmbH, Germany
Aswan University, Egypt
Fujian Agriculture and Forestry University, China

Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2019)

SDN1
CRISPR/Cas

Newe Ya’ar Research Center,
Agricultural Research Organization (ARO), Israel
University of California, USA

Resistance against a protist pathogen: stable resistance against clubroot disease. Clubroot disease is caused by the protist Plasmodiophora brassicae Woronin and can result in a 10-15% yield loss in Brassica species as well as related crops.
(Hu et al., 2023)

SDN1
CRISPR/Cas

Saskatoon Research and Development Centre, Canada

Increased basal immunity and broad spectrum disease resistance.
( Leibman-Markus et al., 2023 )

SDN1
CRISPR/Cas

Volcani Institute
Tel Aviv University, Israel

Virus resistance: Immunity to cucumber vein yellowing virus infection (Ipomovirus) and resistance to the potyviruses Zucchini yellow mosaic virus and Papaya ring spot mosaic virus.
(Chandrasekaran et al., 2016)

SDN1
CRISPR/Cas

Volcani Center, Israel

Viral resistance: Highly efficient resistance against wheat dwarf virus (WDV), an economically important virus. WDV infect both wheat and barley causing severe yield losses. The natural resistance resources are limited.
(Kis et al., 2019)

SDN1
CRISPR/Cas

University of Pannonia
Hungarian Academy of Sciences
Eötvös Loránd University University
Szent István University, Hungary

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease in Southeast Asia and West Africa.
(Wei et al., 2021)

SDN2
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
Agricultural Research Center, Egypt

SDN1
CRISPR/Cas

Central University of Punjab, India
Newe Ya’ar Research Center
Agricultural Research Organization (ARO), Israel

Fungal resistance: resistance to Fusarium graminearum. Fusarium head blight (FHB) is an economically important disease, affecting both yield and grain quality of maize, wheat and barley.
(Brauer et al., 2020)

SDN1
CRISPR/Cas

Ottawa Research and Development Centre, Canada

Viral resistance: reduced viral accumulation and amelioration of virus-induced symptoms by Potato Virus Y.
(Lucioli et al., 2022)

SDN1
CRISPR/Cas

ENEA
Council for Agricultural Research and Economics (CREA), Italy
National Agricultural Research and Innovation Centre, Hungary

Visual detection of maize chlorotic mottle virus (MCMV), one of the important quarantine pathogens in China. This novel method is specific, rapid, sensitive and does not require special instruments and technical expertise.
( Duan et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Yazhou Bay Science and Technology City, China
Alexandria University, Egypt

Traits related to abiotic stress tolerance

Increased drought tolerance: suppresses xylem vessel proliferation, leading to lower water conductance, and reduced water-loss under water-deficit conditions.
(Illouz-Eliaz et al., 2020)

SDN1
CRISPR/Cas

Institute of Plant Sciences and Genetics in Agriculture
The Robert H. Smith Faculty of Agriculture
The Hebrew University of Jerusalem, Israel

Increased root length, which can restore good performance under water stress.
( Gabay et al., 2023 )

SDN1
CRISPR/Cas

University of California
Howard Hughes Medical Institute, USA
University of Haifa, Israel
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Universidad Nacional de San Martín (UNSAM), Argentina
Fudan University
China Agricultural University, China
Karolinska Institutet, Sweden

Increased drought tolerance.
( Abdallah et al., 2022 )

SDN1
CRISPR/Cas

Cairo University, Egypt
Crop Improvement and Genetics Unit, USA

Improved salt stress resistance. Significant increase in the shoot weight, the total chlorophyll content, and the chlorophyll fluorescence under salt stress. Also high antioxidant activities coincided with less reactive oxygen species (ROS).
( Shah Alam et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University, China
Taif University, Saudi Arabia
Alexandria University, Egypt

Reduced cuticle permeability and enhanced drought tolerance.
( He et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University
USA
University of British Columbia, Canada

Increased tolerance to cold stress.
( Teper-Bamnolker et al., 2022 )

SDN1
CRISPR/Cas

The Volcani Institute
The Hebrew University of Jerusalem
Danziger Innovations Limited, Israel

Altered cuticle properties to enhance drought tolerance.
( Negin et al., 2021 )

SDN1
CRISPR/Cas

Weizmann Institute of Science, Israel

Traits related to improved food/feed quality

Fragrance by accumulation of the natural aroma substance 2-acetyl-1-pyrroline (2AP). Fragrance is one of the most important rice quality traits, with 2AP being the major contributor to aroma.
( Tang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hubei Academy of Agriculture Sciences
Guangdong Academy of Agricultural Sciences, China
Agricultural Research Center, Egypt

Important metabolic changes affecting tomato fruit quality. Reduced contents of the anti-nutrient oxalic acid.
( Gago et al., 2017 )

SDN1
ZFN

University of Algarve, Portugal
Centre for Research and Technology Hellas
Technological Educational Institution of Crete, Greece

Altered protein composition due to mutations in seed storage proteins. Two major families of storage proteins, account for about 70% of total soy seed protein. Some major biochemical components influencing the quality of soy food products, for example tofu, are both the quantity and quality of storage proteins in soybean seeds.
( Li et al., 2019 )

SDN1
CRISPR/Cas

Agriculture and Agri-Food Canada
Western University
Harrow Research and Development Centre, Canada
Sun Yat-sen University
Guangdong Academy of Agricultural Sciences
Minnan Normal University
China

Parthenocarpy: seedless tomato. Industrial purposes and direct eating quality.
(Klap et al., 2016)

SDN1
CRISPR/Cas

Agricultural Research Organization, Israel

Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
National Research Council Canada, Canada

Improved starch quality by reducing the levels of amylose, thus increasing the amylopectin content.
( Ali et al., 2023 )

SDN1
CRISPR/Cas

Agricultural Genetic Engineering Research Institute (AGERI)
Ain Shams University Faculty of Agriculture, Egypt

Traits related to increased plant yield and growth

Customize tomato cultivars for urban agriculture: increased compactness and decreased growth cycle of tomato plants.
(Kwon et al., 2020)

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
Cornell University
University of Florida, USA
Wonkwang University, South Korea
Weizmann Institute of Science, Israel

Confer shoot architectural changes for increased resource inputs to increase crop yield.
( Stanic et al., 2021 )

SDN1
CRISPR/Cas

University of Calgary, Canada
SRM Institute of Technology, India

Plant development. Phenotypes consistent with increased GA response: tall and slender with light green vegetation.
(Lor et al., 2014)

SDN1
TALENs

University of Minnesota, USA
Hebrew University of Jerusalem, Israel

Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )

SDN1
CRISPR/Cas

Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea

Altered tree architecture, exhibited pleiotropic phenotypes: including differences in branch angle and stem growth.
(Dutt et al., 2022)

SDN1
CRISPR/Cas

University of Florida, USA
Mansoura University, Egypt

Traits related to industrial utilization

Smaller petunia plants with high flower abundance.
( Abdulla et al., 2024 )

SDN1
CRISPR/Cas

Ondokuz Mayis University, Turkey
Agricultural Research Center (ARC), Egypt

Generating male sterility lines (MLS) and enhanced tolerance against drought stress. Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Secgin et al., 2022 )

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University
Ondokuz Mayıs University, Turkey
Agricultural Research Center (ARC), Egypt

Early heading: in regions with short growing seasons, early maturing varieties to escape frost damage are required.
(Sohail et al., 2022)

SDN1
CRISPR/Cas

China National Rice Research Institute
Northern Center of China National Rice Research Institute
Zhejiang A&
F University, China
Mir Chakar Khan Rind University
Agriculture Research System Khyber, Pakistan
Ministry of Agriculture, Bangladesh
Agriculture Research Center, Egypt

Traits related to herbicide tolerance

Herbicide tolerance: AHAS-inhibiting
(Gocal et al., 2015)

ODM

Cibus, Canada
Cibus, USA

Bispyribac sodium
( Butt et al., 2017 )

SDN2
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia
Agricultural Research Center, Egypt
Rice University, USA

Traits related to product color/flavour

A significant reduction of saponins. Saponins are a source of bitter, and metallic off-flavors in products containing peas.
( Hodgins et al., 2024 )

SDN1
CRISPR/Cas

Universityof Calgary
Universityof Saskatchewan
National Research Council of Canada, Canada

Albino phenotype
( Bánfalvi et al., 2020 )

SDN1
CRISPR/Cas

NARIC Agricultural Biotechnology Institute, Hungary

Improved aroma, flavour and fatty acid (FA) profiles of pea seeds.
( Bhowmik et al., 2023 )

SDN1
CRISPR/Cas

National Research Council Canada (NRC)
University of Calgary
University of Saskatchewan
Agriculture and Agri-Food Canada (AAFC)
St. Boniface Hospital Research, Canada
John Innes Centre, UK

Yellow and orange fruit color.
( Dahan-Meir et al., 2018 )

SDN2
CRISPR/Cas

Weizmann Institute of Science, Israel

Fruit color: tangerine
(Ben Shlush et al., 2021)

SDN2
CRISPR/Cas

The Weizmann Institute of Science, Israel

Traits related to storage performance

Decreased cold-induced sweetening of the potato tubers.
Cold-storage causes undesired sweetening which reduces the quality and the commercial value of the tubers.
( Hassan et al., 2023 )

SDN1
CRISPR/Cas

Agricultural Genetic Engineering Research Institute - Agricultural Research Center
Ain Shams University, Egypt

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour

Traits related to storage performance