Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 17 results

Traits related to biotic stress tolerance

Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)
SDN1
CRISPR/Cas
Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands
Viral resistance: increased resistance to infection with the potato virus Y (PVY) and tolerance to salt and osmotic stress. PVY is one of the most economically important potato pathogens
(Makhotenko et al., 2019)
SDN1
CRISPR/Cas
Russia Moscow State University, Russia
Doka Gene Technologies Ltd, USA
Fungal resistance: Reduced susceptibility to the powdery mildew pathogen (Oidium neolycopersici), a world-wide disease threatening the production of greenhouse- and field-grown tomatoes.
(Santillán Martínez et al., 2020)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands
Significantly enhanced resistance to V. dahliae, and furthermore also to Verticillium albo-atrum and Fusarium oxysporum f. sp. lycopersici (Fol), despite severe growth defects.
( Hanika et al., 2021 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Fungal resistance: Reduced susceptibility to necrotrophic fungi. Necrotrophic fungi, such as Botrytis cinerea and Alternaria solani, cause severe damage in tomato production.
(Ramirez Gaona et al., 2023)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Takii &
Company Limited, Japan

Traits related to abiotic stress tolerance

Increased tolerance to drought trough reducing water loss. Tuber development.
( Gonzales et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Centro Nacional de Biotecnología – CSIC
Universidad Politécnica de Madrid (UPM), Spain

Traits related to improved food/feed quality

Improved digestibility of kafirins, which increases the grain nutritional value.
( Elkonin et al., 2023 )
SDN1
CRISPR/Cas
Federal Centre of Agriculture Research of South-East Region
Institute of Biochemistry and Genetics, Russia
Improved kafirin digestibility, which increases the grain nutritional value.
( Elkonin et al., 2023 )
SDN1
CRISPR/Cas
Federal Centre of Agriculture Research of South-East Region
Institute of Biochemistry and Genetics – Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences, Russia
Glossy sheat phenotype.
( Gerasimova et al., 2023 )
SDN1
CRISPR/Cas
Siberian Branch of the Russian Academy of Sciences
Vavilov Institute of Plant Genetic Resources (VIR)
Siberian Branch of the Russian Academy of Sciences, Russia

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Germany

Traits related to increased plant yield and growth

Increased total kernel number or kernel weight.
( Kelliher et al., 2019 )
SDN1
CRISPR/Cas
Research Triangle Park
University of Georgia, USA
Syngenta Crop Protection, The Netherlands
Altered spike architecture.
( de Souza Moraes et al., 2022 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany

Traits related to industrial utilization

Increasing cross over frequency. Cross over formation during meiosis is essential for crop breeding to introduce favourable alleles controlling important traits from wild relatives into crops.
( de Maagd et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Eggers et al., 2021 )
SDN3
CRISPR/Cas
Solynta
Wageningen University &
Research, The Netherlands
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Shinoyama et al., 2020 )
SDN1
TALENs
Fukui Agricultural Experiment Station
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Japan Science and Technology Agency (JST)
Yokohama City University, Japan
Altai State University, Russia