genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 20 results

Traits related to improved food/feed quality

Improved fatty acid content: increased content of oleic acid, reduced erucic acid levels and slightly decreased polyunsaturated fatty acids content. Fatty acid composition is important for human health and shelf life.
(Shi et al., 2022)

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences, China

Modified fatty acid profile: increased oleic acid, decreased linoleic and linolenic acid content.
(Huang et al., 2020)

SDN1
CRISPR/Cas

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, China

Yellow-seed production, a desirable trait with great potential for improving seed quality in Brassica crops. The formation of seed colour is due to the deposition of the oxidized form of a flavonoid, called proanthocyanidins (PA). Yellow seeds have a higher oil content.
( Zhai et al., 2019 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Sashidhar et al., 2020 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Max-Planck-Institute for Evolutionary Biology, Germany

Altered lignin composition: decreased syringyl monolignol / guaiacylmonolignol (S/G) ratio. The monolignol ratio has been proposed to affect biomass recalcitrance and the resistance to plant disease.
(Cao et al., 2021)

SDN1
CRISPR/Cas

SouthwestUniversity, China
University of Wisconsin, USA

Increasing seed oil content (SOC).
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Huazhong University of Science and Technology, China

Improved fatty acid composition. The content and abundance of fatty acids play an important role in nutritional and processing applications of oilseeds.
( Okuzaki et al., 2018 )

SDN1
CRISPR/Cas

Tamagawa University
Osaka Prefecture University
Tamagawa University, Japan

Decreases in palmitic acid, increased total C18 and reduced total saturated fatty acid contents. Reduced saturated fat content is connected to lowered cardiovascular disease rate.
( Gupta et al., 2012 )

SDN1
ZFN

Dow AgroSciences
Sangamo BioSciences, USA

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia

Low erucic acid (EA) content. Composition of fatty acids affects the edible and processing quality of vegetable oils. EA is potentially to cause health problems.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
National Research Council Canada, Canada

Traits related to industrial utilization

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China
Wageningen University and Research, The Netherlands

Manipulation of self-incompatibility.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Aarhus University
DLF Seeds A/S, Denmark

Manipulation of flowering time to develop cultivars with desired maturity dates. Stabilization of flowering time and period supports efficient mechanised harvesting.
( Ahmar et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Self-incompatibility to prevent inbreeding in hermaphrodite angiosperms via the rejection of self-pollen.
( Dou et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Accelerated domestication of African rice landraces by improving domestication traits such as sheed shattering, lodging and seed yield. The acceleration of the development of high-yield African landrace varieties is important considering that Africa has a strong growing population and prone to food shortage.
( Lacchini et al., 2020 )

SDN1
CRISPR/Cas

University of Milan, Italy
University of Montpellier, France

Generating genic male sterility lines (GMS). GMS can promote heterosis in rapeseed. Compared with other approaches, GMS brings about nearly complete male sterility to a hybrid breeding program.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Northwest A&
F University
Hybrid Rapeseed Research Centre of Shaanxi Province, China

Reversible complete male sterility. Very precise hormone mediated control of male fertility transition showed great potential for hybrid seed production in Brassica species crops.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs
Henan Normal University, China

Male sterility.
( Tu et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang University
Jiaxing Academy of Agricultural Sciences, China

Male sterility.
( Shen et al., 2024 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to improved food/feed quality

Traits related to industrial utilization