genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 13 results

Traits related to improved food/feed quality

Increased grain hardness and reduced grain width. Grain hardness index of hina mutants was 95.5 on average, while that of the wild type was only 53.7, indicating successful conversion of soft barley into hard barley.Grain hardness, defined as the resistance of the kernel to deformation, is the most important and defining quality of barley and wheat.
( Jiang et al., 2022 )

SDN1
CRISPR/Cas

Qinghai Normal University
Chinese Academy of Sciences, China

Ultra-low nicotine level
( Burner et al., 2022 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Improved cadmium tolerance by reducing the Cd transport from vacuole to cytosol in tobacco leaves.
( Jia et al., 2022 )

SDN1
CRISPR/Cas

Henan Agricultural University
Xiamen University, China

Specific differences in grain morphology, composition and (1,3;1,4)-β-glucan content. Barley rich in (1,3;1,4)-β-glucan, a source of fermentable dietary fibre, is useful to protect against various human health conditions. However, low grain (1,3;1,4)-β-glucan content is preferred for brewing and distilling.
( Garcia-Gimenez et al., 2020 )

SDN1
CRISPR/Cas

The James Hutton Institute
University of Dundee, UK
University of Adelaide
La Trobe University, Australia

Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia

Lowering phytate synthesis in seeds. Phytate is an anti-nutritient.
( Vlčko and Ohnoutková, 2020 )

SDN1
CRISPR/Cas

Czech Academy of Sciences, Czech Republic

Lower levels of D hordein. D hordein is one of the storage proteins in the grain, with a negative effect on malting quality.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Qinghai Province Key Laboratory of Crop Molecular Breeding
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China

High-oleic acid content. Oleic acid has better oxidative stability than linoleic acid due to its monounsaturated nature. High levels of linoleic acid reduces the oxidative stability of cottonseed oil, which can cause rancidity, a short shelf life and production of detrimental trans-fatty acids.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

Cotton Research Center of Shandong Academy of Agricultural Sciences
Huazhong Agricultural University, China

Glossy sheat phenotype.
( Gerasimova et al., 2023 )

SDN1
CRISPR/Cas

Siberian Branch of the Russian Academy of Sciences
Vavilov Institute of Plant Genetic Resources (VIR)
Siberian Branch of the Russian Academy of Sciences, Russia

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Germany

Reduced nicotine levels.
Nicotine is an addictive compound leading to severe diseases.
( Singh et al., 2023 )

SDN1
CRISPR/Cas

CSIR-National Botanical Research Institute
Academy of Scientific and Innovative Research (AcSIR)
Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), India

Increased potassium concentrations (K+). Potassium is crucial for improving the quality of tobacco.
( Gao et al., 2024 )

SDN1
CRISPR/Cas

Yunnan Academy of Tobacco Agricultural Sciences/National Tobacco Genetic Engineering
Research Center
Chinese Academy of Agricultural Sciences, China

Reduced nicotine levels. Nicotine is the addictive component in tobacco.
( Jeong et al., 2024 )

SDN1
CRISPR/Cas

Nulla Bio Inc.
Gyeongsang National University
Gyeongsang National University 501 Jinju-daero, South Korea

Zero amylose grain. Amylose levels significantly influence processing of grain.
( Li et al., 2024 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Qinghai University
Qinghai Academy of Agricultural and Forestry
Sciences
Shandong Academy of Agricultural Sciences, China

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Traits related to improved food/feed quality