genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 41 results

Traits related to increased plant yield and growth

Increased grain yield under field drought stress conditions and no yield loss under well-watered conditions.
( Shi et al., 2017 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Early flowering under long day conditions of higher latitudes to spread production of maize over a broad range of latitudes rapidly.
( Huang et al., 2018 )

SDN1
CRISPR/Cas

University of Wisconsin, USA

Haploid induction to accelerate breeding in crop plants.
( Kelliher et al., 2017 )

SDN1
TALENs

Syngenta Seeds, USA

Enhancing grain-yield-related traits by increases in meristem size
( Liu et al., 2021 )

SDN1
CRISPR/Cas

Cold Spring Harbor
University of Massachusetts Amherst, USA

Improved field performance: higher yield, producing on average 5.5 bushels per acre more. Waxy corn.
(Gao et al., 2020)

SDN1
CRISPR/Cas

Corteva Agriscience, USA

Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, Australia

Increased plant yield due to architectural changes. Leaf inclination: maize plants with upright leaves can be planted at higher densities without shading.
(Brekke et al., 2011)

SDN1
CRISPR/Cas

Iowa State University, USA

Increased bending strength. Stalk lodging, which is generally determined by stalk strength, results in considerable yield loss and has become a primary threat to maize yield under high-density planting.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

China Agricultural University, China
Iowa State University, USA

Increased density by early-flowering phenotype under long-day conditions.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Shandong Agricultural University
South China Agricultural University
Chinese Academy of Agricultural Sciences
Guangdong Laboratory for Lingnan Modern Agriculture, China

Semi-dwarf phenotype with increased lodging resistance.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Rapid improvement of domestication traits and genes that control plant architecture, flower production and fruit size. Major productivity traits are improved in an orphan crop.
( Lemmon et al., 2018 )

SDN1
CRISPR/Cas

Cold Spring Harbor
The Boyce Thompson Institute
Cornell University, USA

Increase in plant height, tiller number, grain protein content and yield. 1.5- to 2.8-fold increase in total chlorophyll content in the flag leaf at the grain filling stage. Delayed senescence by 10–14 days. High nitrogen content in shoots under low nitrogen conditions.
( Karunarathne et al., 2022 )

SDN1
CRISPR/Cas

Murdoch University
Department of Primary Industries and Regional Development, Australia

Increased tassel branch number (TBN), one of the important agronomic traits that contribute to the efficiency of seed production.
( Guan et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Root growth angle regulation, among the most important determinants of root system architecture. Root growth angle controls water uptake capacity, stress resilience, nutrient use efficiency and thus yield of crop plants.
( Kirschner et al., 2021 )

SDN1
CRISPR/Cas

University of Bonn
University of Cologne
Leibniz Institute of Plant Genetics and Crop Plant Research Gatersleben
Justus-Liebig-University Giessen, Germany
University of Bologna, Italy

Conferred lodging resistance. Tef is a staple food, and valuable cash crop in Ethiopia. Lodging is a major limitation to its production.
( Beyene et al., 2022 )

SDN1
CRISPR/Cas

Donald Danforth Plant Science Center
Corteva Agriscience
Michigan State University, USA
Ethiopian Institute of Agricultural Research, Ethiopia

Increased water use efficiency, a promising approach for achieving sustainable crop production in changing climate scenarios.
( Blankenagel et al., 2022 )

SDN1
CRISPR/Cas

Technical University of Munich
Max Planck Institute of Molecular Plant Physiology
Helmholtz Center Munich
Heinrich Heine University Düsseldorf, Germany

Improves complex traits such as yield and drought tolerance.
( Lorenzo et al., 2022 )

SDN1
CRISPR/Cas

Center for Plant Systems Biology
Ghent University
Flanders Research Institute for Agriculture Fisheries and Food (ILVO), Belgium

Increased total kernel number or kernel weight.
( Kelliher et al., 2019 )

SDN1
CRISPR/Cas

Research Triangle Park
University of Georgia, USA
Syngenta Crop Protection, The Netherlands

Altered spike architecture.
( de Souza Moraes et al., 2022 )

SDN1
CRISPR/Cas

Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China

Decreased spike rachis node number and increased grain size and weight.
( Fan et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hainan Yazhou Bay Seed Laboratory
Shandong Academy of Agricultural Sciences
China Agricultural University
Hubei Academy of Agricultural Sciences, China

Enlarged grain phenotype.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Hebi Academy of Agricultural Sciences
Henan Agricultural University, China

Traits related to industrial utilization

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Fang et al., 2022 )

SDN1
CRISPR/Cas

University of Science and Technology Beijing
Beijing Solidwill Sci-Tech Co. Ltd., China

CRISPR/Cas

Sichuan Agricultural University
Chengdu Agricultural College
Sichuan Institute of Atomic Energy, China

Enhanced haploid induction. Double haploid breeding based on in vivo haploid induction has been extensively used in maize breeding. The production of haploids depends on haploid inducers.
( Zhong et al., 2019 )

SDN1
CRISPR/Cas

China Agricultural University, China

Haploid induction.
( Li et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University
Longping Agriculture Science Co. Ltd., China

Male sterility.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Northwest A&
F University, China

Induction of haploid plants for the development of good inbred lines for efficient and fast breeding.
( Liu et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Generation of male sterile (MS) lines. MS is a useful tool to harness hybrid vigor for hybrid seed production.
( Chen et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
China Agricultural University, China

Gynoecious phenotype: only female flowers. Advantageous trait for production of hybrid seed by bees under spatial isolation, because it avoids hand emasculation and hand pollination.
(Zhang et al., 2019)

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement
Chinese Academy of Agricultural Engineering Planning and Design, China

Conversion of hulled into naked barley.
( Gasparis et al., 2018 )

SDN1
CRISPR/Cas

National Research Institute
Warsaw University of Life Sciences (SGGW), Poland

SDN1
CRISPR/Cas

DuPont Pioneer, USA

SDN1
CRISPR/Cas

University of Science and Technology
Beijing, China
Beijing Solidwill Sci-Tech Co. Ltd, China

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Improve biofuel production by mediating lignin modification. Lignocellulosic biomasses are an abundant renewable source of carbon energy. Heterogenous properties of lignocellulosic biomass and intrinsic recalcitrance caused by cell wall lignification lower the biorefinery efficiency. Reduced lignin content is desired.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

Korea Institute of Science and Technology (KIST)
University of Science and Technology (UST)
Daejeon, South Korea

Trait stacking. Modern agriculture demands crops carrying multiple traits.
( Ainley et al., 2013 )

SDN1
ZFN

Dow AgroSciences LLC
Sangamo BioSciences, Inc., USA

Haploid induction to accelerate breeding in crop plants.
( Rangari et al., 2023 )

SDN1
CRISPR/Cas

Punjab Agricultural University, India

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Tian et al., 2023 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement, China

Pollen Self-Elimination, which prevents pollen transgene dispersal.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Northwest A&
F University
Hainan Yazhou Bay Seed Lab
Henan Jinyuan Seed Industry Co., China
International Maize and Wheat Improvement Center (CIMMYT), Mexico

Doubled haploids with increased leaf size. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Impens et al., 2023 )

SDN1
CRISPR/Cas

Ghent University
VIB-UGent Center for Plant Systems Biology
Flanders Research Institute for Agriculture, Fisheries and Food (ILVO), Belgium

Improved pollen viability.
( Lv et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences
Mianyang Normal University
South China Agricultural University, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to increased plant yield and growth

Traits related to industrial utilization