Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Plant

Sdn Type

Displaying 50 results

Traits related to biotic stress tolerance

Fungal resistance: Enhanced resistance to the pathogen Sclerotinia sclerotiorum.
(Sun et al., 2018)
SDN1
CRISPR/Cas
Yangzhou University, China
Fungal resistance: contribute to Sclerotinia sclerotiorum resistance.
(Zhang et al., 2022)
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Oilseed rape mutant with non-abscising floral organs. Clerotinia stem rot (SSR), caused by Sclerotinia sclerotiorum is a detrimental fungal disease for oilseed rape. Petal infection is crucial to the prevalence of SSR in oilseed rape. Oilseed rape varieties with abscission-defective floral organs were predicted to be less susceptible to Sclerotinia infection and to have a longer flowering period to enhance tourism income.
( Wu et al., 2022 )
SDN1
CRISPR/Cas
Yangzhou University, China
Fungal resistance: reduced susceptibility to Verticillium longisporum, a pathogen causing Verticillium stem striping. No fungicide treatments are currently available to control this disease.
(Pröbsting et al., 2020)
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
NPZ Innovation GmbH, Germany
Visual detection of brassica yellows virus (BrYV), an economically important virus on cruciferous species. This assay allows for convenient, portable, rapid, low-cost, highly sensitive and specific detection and has great potential for on-site monitoring of BrYV.
( Xu et al., 2023 )
SDN1
CRISPR/Cas
Guizhou University, China
Resistance against a protist pathogen: stable resistance against clubroot disease. Clubroot disease is caused by the protist Plasmodiophora brassicae Woronin and can result in a 10-15% yield loss in Brassica species as well as related crops.
(Hu et al., 2023)
SDN1
CRISPR/Cas
Saskatoon Research and Development Centre, Canada
Fungal resistance: Reduced susceptibility to Verticillium longisporum, fungal pathogen that causes stem striping in Brassica napus and leads to huge yield losses.
(Ye et al., 2024)
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
Hohenlieth-Hof, NPZ Innovation GmbH, Germany
Aswan University, Egypt
Fujian Agriculture and Forestry University, China

Traits related to abiotic stress tolerance

Enhanced drought tolerance
( Wu et al., 2020 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Reduction in cadmium accumulation. Cadmium is a heavy metal, harmful for human health.
( Yao et al., 2022 )
SDN1
CRISPR/Cas
Sichuan University
Science and Technology Innovation Center of Sichuan Modern Seed Industry Group, China
Improved drought tolerance.
( Linghu et al., 2023 )
SDN1
CRISPR/Cas
Hybrid Rapeseed Research Center of Shaanxi Province
Northwest A &
F University, China

Traits related to improved food/feed quality

Improved fatty acid content: increased content of oleic acid, reduced erucic acid levels and slightly decreased polyunsaturated fatty acids content. Fatty acid composition is important for human health and shelf life.
(Shi et al., 2022)
SDN1
CRISPR/Cas
Zhejiang Academy of Agricultural Sciences, China
Modified fatty acid profile: increased oleic acid, decreased linoleic and linolenic acid content.
(Huang et al., 2020)
SDN1
CRISPR/Cas
National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, China
Yellow-seed production, a desirable trait with great potential for improving seed quality in Brassica crops. The formation of seed colour is due to the deposition of the oxidized form of a flavonoid, called proanthocyanidins (PA). Yellow seeds have a higher oil content.
( Zhai et al., 2019 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Sashidhar et al., 2020 )
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel
Max-Planck-Institute for Evolutionary Biology, Germany
Reduced content of saturated fatty acids: low palmitic and high oleic acid. Great potential for improving peanut oil quality for human health.
(Tang et al., 2022)
SDN1
CRISPR/Cas
Qingdao Agricultural University, China
Altered lignin composition: decreased syringyl monolignol / guaiacylmonolignol (S/G) ratio. The monolignol ratio has been proposed to affect biomass recalcitrance and the resistance to plant disease.
(Cao et al., 2021)
SDN1
CRISPR/Cas
SouthwestUniversity, China
University of Wisconsin, USA
Glucoraphanin(GR)-enriched broccoli. Broccoli contains important nutritional components and beneficial phytochemicals. GR, a major glucosinolate (GSL), protects the body against several chronic diseases.
( Kim et al., 2022 )
SDN1
CRISPR/Cas
Sejong University
Jeonbuk National University
Korea Research Institute of Bioscience and Biotechnology
Asia Seed Company Limited, South Korea
Increasing seed oil content (SOC).
( Zhang et al., 2022 )
SDN1
CRISPR/Cas
Huazhong University of Science and Technology, China
Improved fatty acid composition. The content and abundance of fatty acids play an important role in nutritional and processing applications of oilseeds.
( Okuzaki et al., 2018 )
SDN1
CRISPR/Cas
Tamagawa University
Osaka Prefecture University
Tamagawa University, Japan
Decreases in palmitic acid, increased total C18 and reduced total saturated fatty acid contents. Reduced saturated fat content is connected to lowered cardiovascular disease rate.
( Gupta et al., 2012 )
SDN1
ZFN
Dow AgroSciences
Sangamo BioSciences, USA
Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )
SDN1
CRISPR/Cas
Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia
Improved fatty acid content: high oleic acid, decreased linoleic acid content. FA composition is important for human health and shelf life.
(Wen et al., 2018)
SDN1
TALENs
Guangdong Academy of Agricultural Sciences, China
Low erucic acid (EA) content. Composition of fatty acids affects the edible and processing quality of vegetable oils. EA is potentially to cause health problems.
( Liu et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
National Research Council Canada, Canada
Glossy green phenotype and reduced cuticular wax load.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Hunan Agricultural University
Tianjin Kernel Vegetable Research Institute, China
Reduced levels of very long chain saturated fatty acids in kernels, which are associated with revalance of atherosclerosis and cardiovascular disease.
( Huai et al., 2024 )
SDN1
CRISPR/Cas
Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, China
International Crops Research Institute of the Semi-Arid Tropics (ICRISAT), India
Murdoch University, Australia

Traits related to increased plant yield and growth

Increased shatter resistance to avoid seed loss during mechanical harvest.
( Braatz et al., 2017 )
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel, Germany
Increased seeds number per husk, higher seed weight.
( Yang et al., 2018 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Confer shoot architectural changes for increased resource inputs to increase crop yield.
( Stanic et al., 2021 )
SDN1
CRISPR/Cas
University of Calgary, Canada
SRM Institute of Technology, India
Improve plant architecture to increase yield. Plant height and branch number are directly correlated with yield.
( Zheng et al., 2020 )
SDN1
CRISPR/Cas
Ministry of Agriculture, China
Wilkes University, USA
Semi-dwarf phenotype and compact architecture to increase yield. Plant height and branch angle are the major architectural factors determining yield.
( Fan et al., 2021 )
SDN1
CRISPR/Cas
Ministry of Agriculture and Rural Affairs, China
Wilkes University, USA
Early-flowering varieties. The timing of flowering is an important event in the life cycle of flowering plants.
( Jiang et al., 2018 )
SDN1
CRISPR/Cas
Hunan Agricultural University, China
Université de Strasbourg, France
Rapid improvement of domestication traits and genes that control plant architecture, flower production and fruit size. Major productivity traits are improved in an orphan crop.
( Lemmon et al., 2018 )
SDN1
CRISPR/Cas
Cold Spring Harbor
The Boyce Thompson Institute
Cornell University, USA
Increased seed oil content (SOC). SOC is a major determinant of yield and quality.
( Karunarathna et al., 2020 )
SDN1
CRISPR/Cas
Christian-Albrechts-University of Kiel, Germany
Zhejiang University, China

Traits related to industrial utilization

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Manipulation of flowering time to develop cultivars with desired maturity dates. Stabilization of flowering time and period supports efficient mechanised harvesting.
( Ahmar et al., 2021 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Self-incompatibility to prevent inbreeding in hermaphrodite angiosperms via the rejection of self-pollen.
( Dou et al., 2021 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Shinoyama et al., 2020 )
SDN1
TALENs
Fukui Agricultural Experiment Station
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Japan Science and Technology Agency (JST)
Yokohama City University, Japan
Altai State University, Russia
Generating genic male sterility lines (GMS). GMS can promote heterosis in rapeseed. Compared with other approaches, GMS brings about nearly complete male sterility to a hybrid breeding program.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
Northwest A&
F University
Hybrid Rapeseed Research Centre of Shaanxi Province, China
Reversible complete male sterility. Very precise hormone mediated control of male fertility transition showed great potential for hybrid seed production in Brassica species crops.
( Cheng et al., 2023 )
SDN1
CRISPR/Cas
Ministry of Agriculture and Rural Affairs
Henan Normal University, China
Male sterility.
( Tu et al., 2024 )
SDN1
CRISPR/Cas
Zhejiang University
Jiaxing Academy of Agricultural Sciences, China
Male sterility.
( Shen et al., 2024 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Hubei Hongshan Laboratory, China

Traits related to herbicide tolerance

Herbicide tolerance: AHAS-inhibiting
(Gocal et al., 2015)

ODM
Cibus, Canada
Cibus, USA
Glyphosate
( Wang et al., 2021 )

CRISPR/Cas
Huazhong Agricultural University
Anhui Academy of Agricultural Sciences, China
Tribenuron methyl
( Wu et al., 2020 )

BE
Yangzhou University
Shanghai Normal University, China
Herbicide-resistance (ALS-targeting).
( Shi et al., 2023 )

BE
Henan Biological Breeding Center Co.
The Shennong Laboratory, China

Traits related to product color/flavour

Altered color of petals and leaves.
( Li et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Hubei Hongshan Laboratory, China
Yellow colored seed.
( Huang et al., 2023 )
SDN1
CRISPR/Cas
Hunan Academy of Agricultural Sciences
Hunan University of Science and Technology
Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, China
Altered ornamental quality: Increased sensitivity to low temperature, thus affecting leaf margin coloration.
(Zhou et al., 2023)
SDN1
CRISPR/Cas
Shenyang Agricultural University
Breeding and Cultivation of Liaoning Province
Dalian Minzu University
Key Laboratory of Biotechnology and Bioresources Utilization, China

Traits related to storage performance

Enhanced oleic acid to linoleic acid ratio. This adjusted ratio can improve the shelf life of peanut oil.
( Rajyaguru et al., 2024 )
SDN1
CRISPR/Cas
Junagadh Agricultural University, India