genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 54 results

Traits related to biotic stress tolerance

Fungal resistance: enhanced resistance to Phytophthora infestans. Phytophthora infestans causes late blight disease, which is severely damaging to the global tomato industry
(Hong et al., 2021)

SDN1
CRISPR/Cas

Dalian University of Technology
Beijing Academy of Agriculture &
Forestry Sciences
Shenyang Agricultural University/Key Laboratory of Protected Horticulture, China

Viral resistance: improved resistance against tomato yellow leaf curl virus (TYLCV). TYLCV causes significant economic losses in tomato production worldwide.
(Faal et al., 2020)

SDN1
CRISPR/Cas

Ferdowsi University of Mashhad, Iran

Viral resistance: resistance to pepper veinal mottle virusin cherry fruit tomato (Solanum lycopersicum var. cerasiforme)
(Kuroiwa et al., 2021)

SDN1
CRISPR/Cas

INRAE
Université Paris-Saclay
Université de Toulouse, France

Increased jasmonic acid (JA) accumulation after wounding and plant resistance to herbivorous insects.
( Sun et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University, China

Viral resistance: partial resistance to Pepper veinal mottle virus (PVMV) isolate IC, with plants harboring weak symptoms and low virus loads at the systemic level.
(Moury et al., 2020)

SDN1
CRISPR/Cas

INRA, France
Université de Tunis El-Manar
Université de Carthage, Tunisia
Université Felix Houphouët-Boigny, Cote d’Ivoire
Institut de l’Environnement et de Recherches Agricoles, Burkina Faso

Viral resistance: Resistance to Tomato brown rugose fruit virus (ToBRFV), a major threat to the production of tomato.
(Ishikawa et al., 2022)

SDN1
CRISPR/Cas

Institute of Agrobiological Sciences
Takii and Company Limited, Japan

Viral resistance: resistance to potyvirus potato virus Y (PVY), which causes serious yield loss.
(Kumar et al., 2022)

SDN1
CRISPR/Cas

Agricultural Research Organization, Israel

Herbicide resistance: pds (phytoene desaturase), ALS (acetolactate synthase), and EPSPS (5-Enolpyruvylshikimate-3-phosphate synthase)
(Yang et al., 2022)

SDN1
CRISPR/Cas

Chonnam National University, South Korea

Bacterial resistance: enhanced disease resistance to Clavibacter michiganensis subsp. michiganensis infection.
(García-Murillo et al., 2023)

CRISPR/Cas

Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico

Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)

SDN1
CRISPR/Cas

University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA

Fungal resistance: Increased tolerance against Fusarium oxysporum f. sp. lycopersici, causing vascular wilt.
(Ijaz et al., 2022)

SDN1
CRISPR/Cas

University of Agriculture, Pakistan

Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2021)

SDN1
CRISPR/Cas

Central University of Punjab, India
Newe Ya’ar Research Center
Agricultural Research Organization (ARO), Israel

Viral and fungal resistance: Tomato yellow leaf curl virus (TYLCV) and powdery mildew (Oidium neolycopersici), diseases which reduce tomato crop yields and cause substantial economic losses each year.
(Pramanik et al., 2021)

SDN1
CRISPR/Cas

Gyeongsang National University
Pusan National University
R&
D Center, Bunongseed Co., South Korea

Fungal resistance: Reduced susceptibility to the powdery mildew pathogen (Oidium neolycopersici), a world-wide disease threatening the production of greenhouse- and field-grown tomatoes.
(Santillán Martínez et al., 2020)

SDN1
CRISPR/Cas

Wageningen University &
Research, The Netherlands

Fungal resistance: resistance to Oidium neolycopersici, causing powdery mildew.
(Nekrasov et al., 2017)

SDN1
CRISPR/Cas

Max Planck Institute for Developmental Biology, Germany
Norwich Research Park, UK

Bacterial resistance: resistance to different pathogens including Xanthomonas spp., P. syringae and P. capsici.
(de Toledo Thomazella et al., 2016)

SDN1
CRISPR/Cas

University of California, USA

Viral resistance: resistance to pepper mottle virus (PepMoV), causing considerable damage to crop plants.
(Yoon et al., 2020)

SDN1
CRISPR/Cas

Seoul National University
National Institute of Horticultural and Herbal Science, South Korea

SDN1
CRISPR/Cas

Newe Ya’ar Research Center,
Agricultural Research Organization (ARO), Israel
University of California, USA

Fungal resistance: improved resistance to necrotrophic fungus Botrytis cinerea.
(Jeon et al., 2020)

SDN1
CRISPR/Cas

Stanford University, UK
L’Oreal, France
Howard Hughes Medical Institute, USA

Bacterial resistance: Resistance to Pseudomonas syringae DC3000, a widespread pathogen that causes bacterial speck disease of tomato.
(Ortigosa et al., 2019)

SDN1
CRISPR/Cas

Centro Nacional de Biotecnología, Consejo Superior de Investigaciones CientÃficas (CNB-CSIC),Spain

Viral resistance: improved resistance to yellow leaf curl virus (TYLCV).
(Tashkandi et al., 2018)

SDN1
CRISPR/Cas

Princess Nourah bint Abdulrahman University
4700 King Abdullah University of Science and Technology, Saudi Arabia

Differential resistance to tobamovirus.
( Kravchik et al., 2022 )

SDN1
CRISPR/Cas

Enhanced resistance to Botrytis cinerea.
( Huang et al., 2022 )

SDN1
CRISPR/Cas

Beijing University of Agriculture
Capital Normal University, China

Increased basal immunity and broad spectrum disease resistance.
( Leibman-Markus et al., 2023 )

SDN1
CRISPR/Cas

Volcani Institute
Tel Aviv University, Israel

Fungal resistance: strong resistance against Fusarium oxysporum f. sp. lycopersici (Fol), which causes Fusarium Wilt Disease in tomato.
(Debbarma et al., 2023)

SDN1
CRISPR/Cas

CSIR-North East Institute of Science and Technology
Academy of Scientific and Innovative Research
Assam Agricultural University
Central Muga Eri Research and Training Institute
International Crop Research Institute for the Semi Arid Tropics, India

Fungal resistance: increased resistance to Botrytis cinerea.
(Perk et al., 2023)

SDN1
CRISPR/Cas

CONICET—Universidad Nacional de Mar del Plata
Universidad Nacional de La Plata, Argentina

Fungal and bacterial resistance: increased resistance towards the bacterial pathogen Pseudomonas syringae pv. maculicola (Psm) and fungal pathogen Alternaria brassicicola.
(Yung Cha et al., 2023)

SDN1
CRISPR/Cas

Gyeongsang National University, South Korea

Nematode resistance: decreased susceptibility against root-knot nematodes, showing fewer gall and egg masses.
(Noureddine et al., 2023)

SDN1
CRISPR/Cas

Université Côte d’Azur
Université de Toulouse, France
Kumamoto University, Japan

Fungal resistance: Reduced susceptibility to necrotrophic fungi. Necrotrophic fungi, such as Botrytis cinerea and Alternaria solani, cause severe damage in tomato production.
(Ramirez Gaona et al., 2023)

SDN1
CRISPR/Cas

Wageningen University &
Research, The Netherlands
Takii &
Company Limited, Japan

Fast and accurate field screening and differentiation of four major Tobamoviruses infecting tomato and pepper. Tomatoviruses are the most important viruses infecting plants and cause huge economic losses to tomato and pepper crops globally.
( Zhao et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Inspection and Quarantine
China Agricultural University, China

Effective detection of a resistance-breaking strain of tomato spotted wilt virus (TSWV). TSWV causes a great threat to various food crops globally and can cause devastating epidemics.
( Shymanovich et al., 2024 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Detection method for the geminiviruses, tomato yellow leaf curl virus and tomato leaf curl New Delhi virus, which can cause huge economic losses and pose a threat to sustainable agriculture.
( Mahas et al., 2021 )

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology (KAUST), Saudi Arabia

Pospiviroids detection method. Pospiviroids are a major production constraint.
( Zhai et al., 2024 )

SDN1
CRISPR/Cas

Washington State University
USDA-ARS, USA

Fungal resistance: increased tolerance to Late Blight disease, which could be devastating to tomato yields.
(Maioli et al., 2024)

SDN1
CRISPR/Cas

University of Torino, Italy
Ingeniero Fausto Elio/n, Spain
Wageningen University &
Research,

Bacterial resistance: resistance against bacterial spot disease, caused by Xanthomonas species, which could be a devastating to tomato as well as pepper.
(Ortega et al., 2024)

SDN1
CRISPR/Cas

University of California
University of Florida, USA

Fungal resistance: Enhanced resistance against powdery mildew, caused by Oidium neolycopersici, which is a major concern for the productivity of tomato plants.
(Li et al., 2024)

SDN1
CRISPR/Cas

University of Torino, Italy
Wageningen University &
Research, The Netherlands
Shanxi Agricultural University, China

Viral resistance: reduced potato spindle tuber viroid (PSTVd) accumulation and alleviated disease symptoms. PSTVd can threaten tomato production.
(Wei Khoo et al., 2024)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Southwest University
Heilongjiang Academy of Agricultural Sciences
China Agricultural University
Inner Mongolia Zhongjia Agricultural Biotechnology Co. Ltd., China

Traits related to industrial utilization

Accelerated abscission. Plant organ abscission is a process important for development and reproductive success,
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Key Laboratory of Protected Horticulture of Ministry of Education, China
University of California at Davis
Crops Pathology and Genetic Research Unit, USA

Male sterility: mutants did not produce pollen and induced a parthenocarpic fruit set.
(Gökdemir et al., 2022)

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University, Turkey

Parthenocarpy: seedless tomatoes
(Nieves-Cordones et al., 2020)

SDN1
CRISPR/Cas

Centro de Edafología y Biología Aplicada del Segura-CSIC, Spain

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Bao et al., 2022 )

SDN1
CRISPR/Cas

Yunnan Agricultural University
Yunnan Academy of Agriculture Sciences, China

Generating male sterility lines (MLS) and enhanced tolerance against drought stress. Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Secgin et al., 2022 )

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University
Ondokuz Mayıs University, Turkey
Agricultural Research Center (ARC), Egypt

Jointless tomatoes. Pedicel abscission is an important agronomic factor that controls yield and post-harvest fruit quality. In tomato, floral stems that remain attached to harvested fruits during picking mechanically damage the fruits during transportation, decreasing the fruit quality for fresh-market tomatoes and the pulp quality for processing tomatoes.
( Roldan et al., 2017 )

SDN1
CRISPR/Cas

Institute of Plant Sciences Paris-Saclay (IPS2), France
University of Liège, Belgium

Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )

SDN1
CRISPR/Cas

University of California
Emory University, USA
University of Cambridge, UK

Male sterility for hybrid seed production reduces costs and ensures high varietal purity.
( Du et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Beijing Academy of Agriculture and Forestry Sciences
Zhejiang Agricultural and Forestry University, China

SDN1
CRISPR/Cas

Hankyong National University
Hanyang University
Sunchon National University
Chungbuk National University
Tomato Research Center, South Korea

Increasing cross over frequency. Cross over formation during meiosis is essential for crop breeding to introduce favourable alleles controlling important traits from wild relatives into crops.
( de Maagd et al., 2020 )

SDN1
CRISPR/Cas

Wageningen University &
Research, The Netherlands

SDN1
CRISPR/Cas

Northwest A&
F University
Xi’an Jinpeng Seedlings Co. Ltd.
Hybrid Rapeseed Research Center of Shaanxi Province, China

Increased monounsaturated fatty acid contents (MUFAs). Due to their higher thermal-oxidative stability and viscosity relative to other common fatty acids, MUFAs are preferred for industrial uses, for example as biolubricants and biodiesel fuels.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

National Institute of Agricultural Sciences
Korea Advanced Institute of Science and Technology
Chonnam National University
Plant Engineering Research Institute, South Korea

Manipulation of the biosynthesis of bioactive compound alkaloids. Poppy produces many benzylisoquinoline alkaloids (BIAs) used in biomedicines.
( Alagoz et al., 2016 )

SDN1
CRISPR/Cas

Cankiri Karatekin University
Dokuz Eylul University, Turkey

Domestication: Conferred domesticated phenotypes yet retained parental disease resistance (predominately Xanthomonas perforans), and salt tolerance.
(Li et al., 2018)

SDN1
CRISPR/Cas

University of Chinese Academy of Sciences, China

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high seed purity during hybrid seed production.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

Beijing Academy of Agriculture and Forestry Sciences
Chinese Academy of Sciences
China Agricultural University, China

Dwarf plants that retain favourable fruit traits.
( Nagamine et al., 2024 )

SDN1
CRISPR/Cas

University of Tsukuba, Japan

Enhanced oil accumulation in the seed.
( Cai et al., 2024 )

SDN1
CRISPR/Cas

Brookhaven National Laboratory
Stony Brook University
Montana State University, USA

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to industrial utilization