genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 144 results

Traits related to improved food/feed quality

Low amylose content to improve the rice eating quality.
( Mao et al., 2022 )

Guangdong Academy of Agricultural Sciences
Guangdong Key Laboratory of New Technology in Rice Breeding
Guangdong Rice Engineering Laboratory, China

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Shanghai Normal University, China

Fragrant glutinous hybrid rice.
( Tian et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Waxy rice which lacks amylose. Waxy rice is regarded as a high-quality rice variant, also known as glutinous rice. Due to the unique properties of waxy rice starch, it is extensively used in the chemical industry, medicine, and daily human life.
( Fu et al., 2023 )

SDN1
CRISPR/Cas

Chengdu University of Traditional Chinese Medicine
Rice Research Institute of Sichuan Agricultural University
Meishan Dongpo District Agricultural and Rural Bureau, China

Increased contents of GABA, protein, crude fat, and various mineral contents. GABA-rich rice varieties can promote human nutrition, and ensure health.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs, China

Increased amylose content in the seeds, thus a lower Glycemic Index (GI) value. Low GI rice is preferred to avoid a sudden rise in glucose in the bloodstream. Starch with a high GI threatens healthy individuals to get diabetes type II and proves extremely harmful for existing diabetes type II patients.
( Jameel et al., 2022 )

SDN1
CRISPR/Cas

Jamia Millia Islamia
International Centre for Genetic Engineering and Biotechnology, India
King Saud University, Saudi Arabia

Enriched levels of Gamma-amino butyric acid (GABA). GABA lowers blood pressure, has anti-aging effects, and activates the liver and kidney.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

Guangdong Academy of Agricultural Sciences, China

Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)

SDN1
CRISPR/Cas

Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia

Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Khan et al., 2019 )

SDN1
CRISPR/Cas

Zhejiang University
Yangtze University, China

Improved grain quality. The amylose content, gel consistency and pasting viscosity of grain starches are influencing the grain appearance, cooking/eating quality and starch physical characters.
( Zeng et al., 2020 )

SDN1
CRISPR/Cas

State Key Laboratory for Conservation and Utilization of Subtropical Agro‐Bioresources
Guangdong Laboratory for Lingnan Modern Agriculture
South China Agricultural University, China

Improved quality by reduced grain protein content (GPC). High GPC is negatively correlated between protein content and peak viscosity and breakdown value. High GPC is also positively correlated to protein content and hardness.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Jiangsu Key Laboratory of Crop Genetics and Physiology/Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding
Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops
Agricultural College of Yangzhou University, China

Facilitated Isoproturon Metabolism and Detoxification: Improved growth, the Isoproturon (IPU)-induced cellular damage was attenuated, and IPU accumulation was significantly repressed
(Zhai et al., 2022)

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Production of opaque seeds with depleted starch reserves. Reduced starch content and increased amylose content. Accumulation of multiple sugars, fatty acids, amino acids and phytosterols.
( Baysal et al., 2020 )

SDN1
CRISPR/Cas

University of Lleida-Agrotecnio Center
Catalan Institute for Research and Advanced Studies (ICREA), Spain
Royal Holloway University of London, UK

Increased NH4+ and PO43− uptake, and photosynthetic activity under high CO2 conditions in rice. Largely increased panicle weight. Improved grain appearance quality or a decrease in the number of chalky grains.
( Iwamoto et al., 2022 )

SDN1
CRISPR/Cas

Institute of Agrobiological Sciences, Japan

Increased RS. Cereals high in RS may be beneficial to improve human health and reduce the risk of diet-related chronic diseases.
( Biswas et al., 2022 )

SDN1
CRISPR/Cas

Texas A&
M Univ.
Avance Biosciences Inc., USA

Reduced Cd accumulation.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

South China Agricultural University
Guangdong Academy of Sciences, China

Carotenoid-enriched. Carotenoids, the source of pro vitamin A, are an essential component of dietary antioxidants.
( Dong et al., 2020 )

SDN3
CRISPR/Cas

University of California
Innovative Genomics Institute
The Joint Bioenergy Institute, USA

Fragrant rice. Introduction of aroma into any non-aromatic rice varieties.
( Ashokkumar et al., 2020 )

SDN1
CRISPR/Cas

Tamil Nadu Agricultural University, India

Increased lysophospholipid content and enhanced cooking and eating quality. Lysophospholipid (LPL) is derived from the hydrolysis of phospholipids and plays an important role in rice grain quality.
( Khan et al., 2020 )

SDN1
CRISPR/Cas

Zhejiang University, China

Increased carotene accumulation in rice endosperm.
( Shao et al., 2017 )

SDN1
CRISPR/Cas

Key Laboratory of Rice Biology and Genetic Breeding, China

Biofortification: Enhanced Zinc and Manganese tolerance and increased Zinc and Manganese accumulation in rice grains.
(Qiao et al., 2019)

SDN1
CRISPR/Cas

Shenzhen University
University of Chinese Academy of Sciences, China

High-amylose content (up to 56% in apparent amylose content) and resistant starch (up to 35%).
( Luo et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Shanghai Sanshu Biotechnology Co.,
Guangxi Subtropical Crops Research Institute, China

Aromatic three-line hybrid.
( Hui et al., 2021 )

SDN1
CRISPR/Cas

China National Rice Research Institute, China

Increased grain amylose content. Improving grain quality is one of the most important goals in rice breeding. Contribute to the breeding of rice cultivars with better eating and cooking quality, as cooking and eating quality is determined from amylose content.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Hunan Agricultural University
China National Seed Group Co., China

Attenuated toxic cyanogen production. Cassava produces toxic cyanogenic compounds and requires food processing for safe consumption.
( Gomez et al., 2021 )

SDN1
CRISPR/Cas

University of California
Donald Danforth Plant Science Center
Lawrence Berkeley National Laboratory
Okinawa Institute of Science and Technology Graduate University
Chan-Zuckerberg BioHub, USA

High gamma-aminobutyric acid (GABA) content. GABA plays a key role in plant stress responses, growth, development and as a nutritional component of grain can also reduce the likelihood of hypertension and diabetes. Increased amino acid content. Higher seed weight and seed protein content.
( Akama et al., 2020 )

SDN1
CRISPR/Cas

Shimane University
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization
Yokohama City University, Japan

Increased flavonoid content, functioning as allelochemicals and insect deterrents.
( Lam et al., 2019 )

SDN1
CRISPR/Cas

The University of Hong Kong
The Chinese University of Hong Kong
Shenzhen
Zhejiang Academy of Agricultural Sciences
Nanjing Forestry University, China
Kyoto University, Japan

Low Cadmium (Cd) accumulating. Cadmium (Cd) is a non-essential heavy metal that is toxic to virtually all living organisms, including plants.
( Songmei et al., 2019 )

SDN1
CRISPR/Cas

Zhejiang University
Hubei Collaborative Innovation Center for Grain Industry
Zhejiang University
Jiaxing Academy of Agricultural Sciences, China

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Imrpoved rice eating and cooking quality with down-regulated rice grain protein content, which is negatively regulated to ECQ.
( Yang et al., 2022 )

SDN1
CRISPR/Cas

Yangzhou University, China

Improved aleurone layer with enhanced grain protein content. Improved grain nutritional quality by improved accumulation of essential dietary minerals (Fe, Zn, K, P, Ca) in the endosperm of rice grain. Improved root and shoot architecture.
( Achary et al., 2021 )

SDN1
CRISPR/Cas

International Centre for Genetic Engineering and Biotechnology, India

Generation of a new glutinous Photothermosensitive Genic-Male-Sterile (PTGMS) line with a low amylose content. PTMGS line combines high-quality and high-light-efficiency use, disease and stress resistance.
( Teng et al., 2021 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Reduction of amylose content (AC). AC is the predominant factor determining rice eating and cooking quality.
( He et al., 2020 )

SDN1
CRISPR/Cas

Northeast Agricultural University
Chinese Academy of Sciences
Jiangsu Academy of Agricultural Sciences
Northeast Agricultural University, China

Reduction in cadmium accumulation. Cadmium is a heavy metal, harmful for human health. Cadmium accumulation represents a severe threat to people consuming rice as a staple food.
( Yang et al., 2019 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Chinese Academy of Sciences, China

High-quality sugar production by rice (98% sucrose content). Carbohydrates are an essential energy-source. Sugarcane and sugar beet were the only two crop plants used to produce sugar.
( Honma et al., 2020 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University, China
Faculty of Engineering
Kitami Institute of Technology
NagoyaUniversity
Tokyo Metropolitan University, Japan
Carnegie Institution for Science, USA

Reduce malnutrition by decreasing antinutrient phytic acid (PA) and increasing Iron and Zinc accumulation. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Ibrahim et al., 2021 )

SDN1
CRISPR/Cas

Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan

Production of high amylose and resistant starch rice. Starch accounts for 80 to 90% of the total mass of rice seeds and is low in resistant starch (RS), which is beneficial in preventing various diseases. Starch with high amylose content (AC) and RS have a lower GI value. Foods with low GI value have beneficial effects on glycemic control.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

National Chiayi University
Taiwan Agricultural Research Institute Chiayi Agricultural Experiment Branch, Taiwan

Fragrance by accumulation of the natural aroma substance 2-acetyl-1-pyrroline (2AP). Fragrance is one of the most important rice quality traits, with 2AP being the major contributor to aroma.
( Tang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hubei Academy of Agriculture Sciences
Guangdong Academy of Agricultural Sciences, China
Agricultural Research Center, Egypt

Improved amylose levels to influence grain eating and cooking quality (ECQ).
( Huang et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University, China

Reduce or eliminate amylose content in root starch. Amylose influences the physicochemical properties of starch during cooking and processing.
( Bull et al., 2018 )

SDN1
CRISPR/Cas

Institute of Molecular Plant Biology, Switzerland

Improve glutinosity in elite varieties. Decreased amylose content without affecting other desirable agronomic traits.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University
University of Queensland, USA

Fragrant rice.
( Shan et al., 2015 )

SDN1
TALENs

Chinese Academy of Sciences, China

Increased amylose content. Cereals high in amylose content (AC) and resistant starch (RS) offer potential health benefits and reduce risks of diseases such as coronary heart disease, diabetes and certain colon and rectum cancers.
( Sun et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA
University of Liege, Belgium

Reduced arsenic content, a highly toxic metalloid harming human health. Inorganic Arsenic is listed as a carcinogen.
( Ye et al., 2017 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Altered fatty acid composition. High oleic/low linoleic acid rice. Oleic acid has potential health benefits and helps decrease lifestyle disease.
( Abe et al., 2018 )

SDN1
CRISPR/Cas

National Agriculture and Food Research Organization, Japan

Reduced cesium content. The production of radiocesium in food in contaminated soils is a serious health concern.
( Nieves-Cordones et al., 2017 )

SDN1
CRISPR/Cas

Université Montpellier, France

Reduced cadmium content. Cadmium poses a health treath, as it is a highly toxic heavy metal for most living organisms.
( Tang et al., 2017 )

SDN1
CRISPR/Cas

Hunan Agricultural University, Hunan Hybrid Rice Research Center, Normal University, China

Carotenoid accumulation to solve the problem of vitamin A deficiency that is prevalent in developing countries.
( Endo et al., 2019 )

SDN1
CRISPR/Cas

National Agriculture and Food Research Organization
Ishikawa Prefectural University, Japan

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia

Fragrant rice by introducing aroma into non-aromatic rice varieties. The genome edited fragrant rice was then used as starting material for molecular breeding to introduce both fragrance and high anthocyanin levels in rice.
( Shi et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agriculture Sciences (CAAS)
Tianjin Academy of Agricultural Sciences
Chengdu National Agricultural Science and Technology Center, China

Lowered amylose content and viscosity, risen gel consistency and gelatinization temperature values, all resulting in improved eating and cooking quality.
( Song et al., 2023 )

SDN1
CRISPR/Cas

Jiangsu University
Institute of Food Crops
Yangzhou University, China

Reduced grain chalkiness.
( Gann et al., 2023 )

SDN1
CRISPR/Cas

Cell and Molecular Biology Program
Department of Chemistry and Biochemistry
University of Arkansas at Little Rock, USA

Reduced levels of polybrominated diphenyl ethers, organic pollutants which have great ecological and health risks, in the edible parts.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Zhejiang University
Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, China

Decreased cadmium accumulation in rice grain, while leaving important agronomic traits including yield, unaffected. Cadmium poses a health threat, as it is a highly toxic heavy metal for most living organisms
( Luo et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of the Chinese Academy of Sciences
China National Rice Research Institute
Southern University of Science and Technology, China

Rice grain with a reduced amino acid and total protein content without affecting the agronomic traits of the plant. Additionally, the grain showed improved cooking and eating quality.
( Yang et al., 2023 )

SDN1
CRISPR/Cas

Yangzhou University, China

Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia

High amylose content. High-amylose starches are digested slowly which could provide increased satiety and reduced risk of diabetes, cardiovascular disease and colorectal cancer.
( Kim et al., 2023 )

SDN1
CRISPR/Cas

Kyungpook National University
National Institute of Crop Science, South Korea

Reduced arsenic (As) accumulation in rice grain. Inorganic As is a carcinogen and decreasing the accumulation would improve the food safety of rice.
( Xu et al., 2024 )

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Slender grains in bold grain varieties.
( Shanthinie et al., 2024 )

SDN1
CRISPR/Cas

Tamil Nadu Agricultural University, India

Decrease in percentage of grains with chalkiness and chalkiness degree.
( Fan et al., 2024 )

SDN1
CRISPR/Cas

Yangtze University
Ningbo Academy of Agricultural Science
Yichang Academy of Agricultural Sciences, China

Traits related to increased plant yield and growth

Improvement of yield by reducing the "easy to shatter" trait. Reduced seed shattering ensures better stability during the harvesting processes and improved yields.
( Sheng et al., 2020 )

SDN1
CRISPR/Cas

Hunan Agricultural University
Hunan Hybrid Rice Research Center
Hunan Academy of Agricultural Sciences, China

Increased yield under different environmental conditions: well-watered, drought, normal nitrogen and low nitrogen field conditions and at multiple geographical locations.
(Wang et al., 2020)

SDN1
CRISPR/Cas

Sinobioway Bio-Agriculture Group Co.
Ltd
Corteva Agriscience
Johnston, USA

Improved rice photosynthetic efficiency and yield: increased light saturation points, stomatal conductance, light tolerance and photosynthetic yields.
(Ye et al., 2021)

SDN1
CRISPR/Cas

South China Agricultural University, China

Semi-dwarf phenotype to improve product and lodging resistance.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, China

Control grain size and seed coat color.
( Tra et al., 2021 )

International Rice Research Institute, Philippines
Dahlem Center of Plant Sciences Freie UniversitÃ¤t, Germany
Synthetic Biology, Biofuel and Genome Editing R&
D Reliance Industries Ltd, India

Increased yield potential by nitrogen use efficiency. Nitrogen fertilizer has been applied broadly to increase yield. However, low nitrogen use efficiency causes environmental pollution and ecological deterioration by the nitrogen fertilizers.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Zhengzhou University, China

Improved grain yield by modulating pyruvate enzymes and cell cycle proteins, leading to increased grain size. The grain size is a major determinant for rice yield and a vital trait for domestication and breeding.
( Usman et al., 2020 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Improved yield and fragrance.
( Usman et al., 2020 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Early flowering and maturity. Flowering time (heading date) is an important trait for crop yield and cultivation.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Sinobioway Bio-Agriculture Group, Co., China
Corteva™ Agriscience, USA

Plant architecture: high tillering and reduced height.
(Butt et al., 2018)

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia

Improved nitrogen use efficiency.
( Li et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
University of California, USA

Improvement of grain weight. Longer panicle.
( Xu et al., 2016 )

SDN1
CRISPR/Cas

China National Rice Research Institute, China
China Three Gorges University, China

Altered grain number per panicle and increased seed weight.
( Li et al., 2016 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Altered grain number per panicle.
( Shen et al., 2016 )

SDN1
CRISPR/Cas

National Rice Research Institute, China

Increased seed weight.
( Hu et al., 2018 )

SDN1
CRISPR/Cas

Fudan University, China

Increased seed weight.
( Shen et al., 2017 )

SDN1
CRISPR/Cas

Yangzhou University, China

Increased seed weight.
( Ji et al., 2017 )

SDN1
CRISPR/Cas

Agronomy College of Henan Agricultural University, China

Genetic diversity.
( Shen et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
Yangzhou University, China

Promote outgrowth buds and increase tiller number.
( Lu et al., 2017 )

SDN1
CRISPR/Cas

Wuhan Institute of Bioengineering
Huazhong Agricultural University
Chinese Academy of Sciences, China

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas. Complete abolition of pollen development.
( Lee et al., 2016 )

SDN1
CRISPR/Cas

Kyung Hee University, South Korea

SDN1
CRISPR/Cas

Shanghai Jiao Tong University, China

SDN1
CRISPR/Cas

South China Agricultural University, China

Regulation of pollen tube growth. The tube grows in female reproductive tissues to transport two sperm cells into the embryo sac for double fertilization during sexual reproduction.
( Liu et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences, China

Increased grain number per main panicle and an increased seed settling rate.
( Qian et al., 2017 )

SDN1
CRISPR/Cas

China Agricultural University, China

Grain yield, regulation of seed development.
( Yuan et al., 2017 )

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Generation of important yield-related trait characteristics: dense and erect panicles and reduced plant height.
(Wang et al., 2017)

SDN1
CRISPR/Cas

Syngenta Biotechnology, China

Longer grains and increased glume cell length.
( Sheng et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Chinese Academy of Sciences, China

Reduced seed dormancy: rapid and uniform germination of seeds is important for rice production. Mutant seeds began to germinate 1 day after sowing, while WT seeds needed 2 days.
(Jung et al., 2019)

SDN1
CRISPR/Cas

Hankyong National University
Chungbuk National University
Hanyang University, China
Central Luzon State University, Philippines

Plants with longer primary roots and more crown roots, as well as increased sensitivity to auxins and cytokinins. The rice root system is important for growth.
( Mao et al., 2019 )

SDN1
CRISPR/Cas

Fudan University
Sichuan Agricultural University
Shanghai Normal University
Chinese Academy of Sciences, China

Enhanced rice grain yield by decoupling panicle number and size
( Song et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Shandong Agricultural University
Hainan Yazhou Bay Seed Laboratory, China

Semi-dwarf phenotype. Plant height is an important agronomic trait of rice, it directly affects the yield potential and lodging resistance.
( Han et al., 2019 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University
Guangxi University, China

Semi-dwarf phenotype with desired agronomic traits: tolerance to low phosporus levels and broad-spectrum resistance to diseases and insects.
(Hu et al., 2019)

SDN1
CRISPR/Cas

China National Rice Research Institute, China

Range of beneficial phenotypes: additional tillers and smaller culms and panicles.
(Cui et al., 2020)

SDN1
CRISPR/Cas

China National Rice Research Institute
Huazhong Agricultural University, China
Yangzhou University, Nagoya University, Japan

Increased grain yield without side effect.
( Gho et al., 2022 )

SDN1
CRISPR/Cas

Kyung Hee University, South Korea
International Rice Research Institute, Philippines

Improved rice grain shape and appearance quality. Potential application in breeding of rice varieties with optimized grain morphologies. Slender grain shape.
( Zhao et al., 2018 )

SDN1
CRISPR/Cas

Yangzhou University, China

Increased yield.
( Zhou et al., 2019 )

SDN1
CRISPR/Cas

University of Electronic Science and Technology of China
Xichang University, China
University of Maryland, USA

Promoted rice growth and productivity.
( Miao et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University, USA

Increased yield.
( Huang et al., 2018 )

SDN1
CRISPR/Cas

Yunnan University
Chinese Academy of Sciences
BGI-Baoshan, China

Increased grain size and modulated shoot architecture.
( Miao et al., 2020 )

SDN1
CRISPR/Cas

Zhejiang A&
F University
Nanchang University
Chinese Academy of Sciences, China
Purdue University, USA

Dwarf and high tillering phenotypes.
( Yang et al., 2017 )

SDN1
CRISPR/Cas

Shenzhen University
The Chinese University of Hong Kong, China

Dwarf stature and a lesion-mimic phenotype. Fungal resistance: enhanced resistance to the pathogen Magnaporthe oryzae. Increased content of salicylic acid and induced plant defense responses.
(Ma et al., 2018)

SDN1
CRISPR/Cas

Peking University
Chinese Academy of Agricultural Sciences, China

Improved grain yield by promoting outgrowth buds and increasing tiller number.
( Lu et al., 2018 )

SDN1
CRISPR/Cas

Wuhan Institute of Bioengineering
Huazhong Agricultural University, China

Improved grain length and weight by promoting cell proliferation in spikelet hull
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Chongqing University, China

Improved grain quality without severe yield penalty under nitrogen reduction conditions.
( He et al., 2022 )

SDN1
CRISPR/Cas

Rice Research Institute of Shenyang Agricultural University
Tianjin Tianlong Science and Technology Co. LTD.
National Japanica Rice Research and Development Center, China

Improved rice yield and immunity.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Chinese Academy of Agricultural Sciences, China

Higher yield than wild-type (WT) plants due to increased grain number per panicle, elevated grain weight, and enhanced harvest index.
( Wei et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Shanghai Normal University, China

Improved grain length and weight by promoting cell proliferation.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Chongqing University, China

Increased water use efficiency without growth reductions in well-watered conditions.
( Blankenagel et al., 2022 )

SDN1
CRISPR/Cas

Technical University of Munich
Max Planck Institute of Molecular Plant Physiology
German Research Center for Environmental Health
KWS SAAT SE &
Co.KGaA
Université Technique de Munich
Heinrich Heine University, Germany
LEPSE - Écophysiologie des Plantes sous Stress environnementaux, France

Increased rice grain size and yield.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

China National Seed Group Co. Ltd., China

Conferred lodging resistance. Tef is a staple food, and valuable cash crop in Ethiopia. Lodging is a major limitation to its production.
( Beyene et al., 2022 )

SDN1
CRISPR/Cas

Donald Danforth Plant Science Center
Corteva Agriscience
Michigan State University, USA
Ethiopian Institute of Agricultural Research, Ethiopia

Increased grain size and chalkiness.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Henan Agricultural University, China

Increased grain size.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

China National Rice Research Institute
Huazhong Agricultural University
Nanchong Academy of Agricultural Sciences, China

Increased grain number due to increased meristem activity and enhanced panicle branching.
( Li et al., 2013 )

SDN1
ZFN

Chinese Academy of Sciences
National Hybrid Rice Research and Development Center
Chinese Academy of Agricultural Sciences
China National Hybrid Rice Research and Development Center
Wuhan University, China

Delayed heading date, increased yield and reduced chalkiness under field high temperature stress.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Academy of Agricultural Sciences

Hubei Hongshan Laboratory, China

OsGEF5 and OsGDI1 single mutants show significantly reduced height and longer and thinner grains.
( Shad et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory, China

Increased grain yield under phosphorus-deficient conditions.
( Ishizaki et al., 2022 )

SDN1
CRISPR/Cas

Japan International Research Center for Agricultural Sciences (JIRCAS), Japan

Early flowering time. Flowering time (heading date) is an important trait for crop yield and cultivation.
( Yin et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University, China

Accelerated seedling growth. Because seedling growth and development are the basis of rice tillering and reproduction, rapid seedling growth and fast sprouting from the soil are vital for the emergence rate and yield.
( Teng et al., 2023 )

SDN1
CRISPR/Cas

Hangzhou Normal University
Inner Mongolia University
Zhejiang Academy of Agricultural Sciences
Chinese Academy of Agricultural Sciences, China

Longer root hairs. Root hairs effectively enlarge the soil-root contact area and play essential roles for nutrient and water absorption.
( Yang et al., 2023 )

SDN1
CRISPR/Cas

Zhejiang University
Linyi University
Hunan Agricultural University, China

Improved yield under short day conditions.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

South China Agricultural University, China

Increased nitrogen utilization efficiency under high nitrate concentrations.
( Hang et al., 2023 )

SDN1
CRISPR/Cas

Guizhou University
Guangdong Provincial Key Laboratory of Applied Botany
Guangdong Academy of Agricultural Sciences, China

Increased stomatal density, stomatal conductance, photosynthetic rate and transpiration rate. Fine tuning the stomatal traits can enhance climate resilience in crops.
( Rathnasamy et al., 2023 )

SDN1
CRISPR/Cas

Tamil Nadu Agricultural University
Sugarcane Breeding Institute, India

Enhanced photosynthesis.
( Caddell et al., 2023 )

SDN1
CRISPR/Cas

United States Department of Agriculture - Agricultural Research Service (USDA ARS)
University of California at Berkeley
Utah State University
Texas A&
M University, USA

Altered plant architecture along with a shorter plant height, grain size and increased spikelets and grain density.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shanghai Agrobiological Gene Center, China

Increased tiller number and grain yield.
( Cui et al., 2023 )

SDN1
CRISPR/Cas

The University of Tokyo
Kyoto University
National Institute of Crop Science, Japan

Leaf inclination: the leaf angle is a trait that contributes to crop yield determination.
(Trionfini et al., 2023)

SDN1
CRISPR/Cas

Universidad Nacional del Litoral, Argentina

Increased breaking force, leading to improved lodging resistance.
( Dang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University/Key Laboratory of Northern geng Super Rice Breeding, China

Super-dwarf phenotype. Rice plants with compact growth habits and reduced plant height can be useful in some environments.
( Peng et al., 2023 )

SDN1
CRISPR/Cas

Hunan Agricultural University
Chinese Academy of Agricultural Sciences
Agricultural College of Yangzhou University
Tianjin Academy of Agriculture Sciences, China

Improved lodging resistance in later growth stages due to shorter plant height with enhanced resistance to rice blast.
( Gang et al., 2023 )

SDN1
CRISPR/Cas

Huaiyin Institute of Agricultural Science/Huai'
an Key Laboratory of Agricultural Biotechnology
Huaiyin Normal University
China National Rice Research Institute, China

Reduction of plant height through accumulation of ceramides. Plant height is an important agronomic trait of rice, it directly affects the yield potential and lodging resistance.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Nanchang University
Henan Agricultural University, China
Hokkaido University, Japan

Improved nitrogen use efficiency, growth and yield in low nitrogen environment.
( Liu et al., 2023 )

SDN1
CRISPR/Cas

The University of Tokyo, Japan

Early heading phenotype that escapes from cold stress and achieves high yield potential.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Institute of Lianyungang Agricultural Science of Xuhuai Area/Lianyungang Institute of Agricultural Sciences
Chinese Academy of Agricultural Sciences, China

Delayed heading date with improved yield-related traits e.g. height, tiller number and grain weight.
( Li et al., 2023 )

SDN1
CRISPR/Cas

South China Agricultural University
Guangdong Laboratory for Lingnan
Modern Agriculture, China

Improved spikelet number per panicle led to increased grain yield per plant.
( Ludwig et al., 2023 )

SDN1
CRISPR/Cas

International Rice Research Institute (IRRI), Philippines
University of Pavia, Italy

Delayed flowering, which can increase grain yield and quality.
( Zhou et al., 2024 )

SDN1
CRISPR/Cas

Northeast Forestry University
Chinese Academy of Sciences
Graduate University of Chinese Academy of Sciences
Beidahuang Group Erdaohe Farm CO., China

Increased grain yield and quality.
( Luo et al., 2024 )

SDN1
CRISPR/Cas

Guizhou University, China
King Saud University, Saudi Arabia

Increased grain yield when grown at low latitudes.
( Song et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences
Zhejiang A&
F University, China

Improved lodging resistance and biomass saccharification.
( Wang et al., 2024 )

SDN1
CRISPR/Cas

Shenyang Agricultural University, China

Enhanced tillering and yield.
( Jin et al., 2024 )

SDN1
CRISPR/Cas

Guizhou University, China

Longer rice grains with reduces plant height.
( Xu et al., 2024 )

SDN1
CRISPR/Cas

Rice Research Institute of Shenyang Agricultural University
Shenyang Agricultural University, China

Increased rice grain yield under field conditions.
( Li et al., 2024 )

SDN1
CRISPR/Cas

Sichuan Agricultural University
Nanchong Academy of Agricultural Science
Neijiang Academy of Agricultural Science, China

Delayed flowering.
( Kim et al., 2024 )

SDN1
CRISPR/Cas

Myongji University, Korea

Earlier heading date. Heading date is one of the key agronomic traits that determines adaptation of rice cultivars.
( Wei et al., 2024 )

SDN1
CRISPR/Cas

Yangzhou University
Jiangsu Ruihua Agricultural Technology Co. Ltd, China

Increased grain length and yield.
( Zhang et al., 2024 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Ningbo University, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to improved food/feed quality

Traits related to increased plant yield and growth