Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Sdn Type

Displaying 46 results

Traits related to improved food/feed quality

Reducing polyunsaturated fatty acids content and increased content of monounsaturated fatty acids. High levels of polyunsaturated fatty acids in natural soybean oil renders the oil susceptible to the development of unpalatable flavors and trans fatty acids.
( Fu et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Reduced phytic acid content in soybean seeds. Monogastric animals are unable to digest phytic acid, making phytic acid phosphorous in animal waste one of the major causes of environmental phosphorus pollution.
( Song et al., 2022 )
SDN1
CRISPR/Cas
Dong-A University
Korea Research Institute of Bioscience Biotechnology (KRIBB), South Korea
Improved seed protein content.
( Shen et al., 2022 )
SDN1
CRISPR/Cas
Corteva Agriscience
University of Arizona, USA
Enhanced soybean aroma and functional marker for improving soybean flavor.
( Qian et al., 2022 )
SDN1
CRISPR/Cas
Zhejiang Academy of Agricultural Science
Ministry of Agriculture and Rural Affairs of China
Zhejiang University of Technology
Zhejiang Academy of Agricultural Sciences, China
High-amylose content (up to 56% in apparent amylose content) and resistant starch (up to 35%).
( Luo et al., 2021 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
Shanghai Sanshu Biotechnology Co.,
Guangxi Subtropical Crops Research Institute, China
Attenuated toxic cyanogen production. Cassava produces toxic cyanogenic compounds and requires food processing for safe consumption.
( Gomez et al., 2021 )
SDN1
CRISPR/Cas
University of California
Donald Danforth Plant Science Center
Lawrence Berkeley National Laboratory
Okinawa Institute of Science and Technology Graduate University
Chan-Zuckerberg BioHub, USA
Altered protein composition due to mutations in seed storage proteins. Two major families of storage proteins, account for about 70% of total soy seed protein. Some major biochemical components influencing the quality of soy food products, for example tofu, are both the quantity and quality of storage proteins in soybean seeds.
( Li et al., 2019 )
SDN1
CRISPR/Cas
Agriculture and Agri-Food Canada
Western University
Harrow Research and Development Centre, Canada
Sun Yat-sen University
Guangdong Academy of Agricultural Sciences
Minnan Normal University
China
Generation of seed lipoxygenase-free soybean. Lipoxygenases are responsible for an unpleasant beany flavor by the oxidation of unsaturated fatty acids, restricting human consumption.
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University
Hebei Academy of Agricultural and Forestry Sciences, China
Increased soya bean isoflavone content and resistance to soya bean mosaic virus. Isoflavonoids play a critical role in plant-environment interactions and are beneficial to human health.
( Zhang et al., 2020 )
SDN1
CRISPR/Cas
Nanjing Agricultural University
Anhui Academy of Agricultural Science
Guangzhou University, China
High oleic, low linoleic and alpha-linolenic acid phenotype. High concentration of linoleic and alpha-linolenic acids causes oxidative instability.
( Do et al., 2019 )
SDN1
CRISPR/Cas
University of Missouri, USA
Vietnam Academy of Science and Technology, Vietnam
Reduced raffinose family oligosaccharide (RFO) levels in seeds. Human and other monogastric animals cannot digest major soluble carbohydrates, RFOs.
( Le et al., 2020 )
SDN1
CRISPR/Cas
Vietnam Academy of Science and Technology, Vietnam
University of Missouri, USA
Leibniz Institute of Plant Genetics and Crop Plant Research
Germany
High oleic acid, low linoleic content.
( al Amin et al., 2019 )
SDN1
CRISPR/Cas
Jilin Agricultural University, China
Low polyunsaturated fats content. Soybean oil is high in polyunsaturated fats and is often partially hydrogenated. The trans-fatty acids produced through hydrogenation pose a health threat.
( Haun et al., 2014 )
SDN1
TALENs
Cellectis plant sciences Inc., USA
High oleic and low linolenic oil to improve nutritional characteristics, increase shelf-life and frying stability.
( Demorest et al., 2016 )
SDN1
TALENs
Cellectis plant science Inc.
Calyxt, USA
Reduce or eliminate amylose content in root starch. Amylose influences the physicochemical properties of starch during cooking and processing.
( Bull et al., 2018 )
SDN1
CRISPR/Cas
Institute of Molecular Plant Biology, Switzerland
Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )
SDN1
CRISPR/Cas
Zhejiang University, China
La Trobe University, Australia
High levels of monounsaturated fatty acids (MUFAs) in soybean seed oil. High MUFA content in vegetable oils can lead to significant health benefits and improve the oxidative stability, which are essential for both food usage and biodiesel (and other renewable resource) synthesis.
( Li et al., 2023 )
SDN1
CRISPR/Cas
Northeast Agricultural University, China
Reduced content of trypsin inhibitors, one of the most abundant anti-nutritional factors in soybean seeds. Reduction of trypsin inhibitors leads to improved. digestibility of soybean meal.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
Virginia Tech, USA
Reduced levels of phytic acid (PA). PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Krishnan et al., 2023 )
SDN1
CRISPR/Cas
ICAR-Indian Agricultural Research Institute (IARI)
Bharathidasan University, India
Improved fatty acid content: high oleic acid, decreased linoleic acid content to improve nutritional characteristics, increase shelf-life and frying stability.
(Zhang et al., 2023)
SDN1
CRISPR/Cas
Jilin Agricultural University, China
Reduced content of anti-nutritional factors in soybean seeds, leading to improved digestibility.
( Figliano et al., 2023 )
SDN1
CRISPR/Cas
UEL - Universidade Estadual de Londrina, Portugal
Decreased storage-proteins, which allows improved forein protein production in seed.
( Ha et al., 2023 )
SDN1
CRISPR/Cas
Dong-A University
South Korea
β-conglycinin deficiency, which lowers allergenicity and increases nutritional value.
( Song et al., 2024 )
SDN1
CRISPR/Cas
Northeast Agricultural University/Key Laboratory of Soybean Biology of the Chinese Education Ministry
Harbin Normal University
Keshan Branch of Heilongjiang Academy of Agricultural Sciences
Jilin Agricultural University, China
USDA Agricultural Research Service
University of Missouri, USA

Traits related to increased plant yield and growth

Improved high-density yield and drought/osmotic stress tolerance.
( Chen et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Shanxi Academy of Agricultural Sciences, China
Texas Tech University, USA
Regulate shade avoidance. Soybean displays the classic shade avoidance syndrome (SAS), which leads to yield reduction and lodging under density farming conditions.
( Lyu et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Jilin Agricultural University
Shandong Agricultural University
Northeast Agricultural University, China
Increasing the number of seeds per pod (NSPP), an important yield determinant.
( Cai et al., 2021 )
SDN1
CRISPR/Cas
South China Agricultural University, China
Control flowering time, an important determinant for soybean yield and adaptation.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
University of Chinese Academy of Sciences
Guangzhou University
Agronomy College of Heilongjiang Bayi Agricultural University
Nanjing Agricultural University
Heilongjiang Academy of Agricultural Sciences, China
Late flowering. Photoperiod sensitivity limits geographical range of cultivation.
( Cai et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Enhanced photosynthesis and increases seed yield.
( Hu et al., 2022 )
SDN1
CRISPR/Cas
Nanjing Agricultural University
Chinese Academy of Sciences
Henan Institute of Science and Technology, China
Compact architecture with a smaller petiole angle than wild-type plants.
( Zhang et al., 2022 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University
Beijing Vocational College of Agriculture
Xiamen University, China
Altered plant architecture to inrease yield: increased node number on the main stem and branch number.
(Bao et al., 2019)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
Duy Tan University, Vietnam
RIKEN Center for Sustainable Resource Science, Japan
Increased nodule numbers. Soybean is a globally important crop for oil production and protein for human diet.
( Bai et al., 2019 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University
Nanchang University, China
Overexpression causes strongly promoted stem elongation, lower expression resulted in dwarf phenotype.
( Mu et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Enhanced performance of soybean under dense conditions.
( Ji et al., 2022 )
SDN1
CRISPR/Cas
Academy of Agricultural Sciences
Southern University of Science and Technology, China
Promoting nodulation: up-regulation of expression levels of genes involved in nodulation. Nitrogen-fixing symbiotic nodules strongly up regulate yield.
(Wang et al., 2022)
SDN1
CRISPR/Cas
Beijing Institute of Technology
Chinese Academy of Agricultural Sciences, China
Improved pod shattering resistance. Pod shattering has been a negatively selected trait in soybean domestication and breeding as it can lead to devastating yield loss of soybean.
( Zhang et al., 2022 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University
Heilongjiang Bayi Agricultural University
Hebei Academy of Agricultural and Forestry Sciences, China
Reduction of soybean plant height and shortening of the internodes. The height of the soybean plant is a key trait that significantly impacts the yield.
( Cheng et al., 2019 )
SDN1
CRISPR/Cas
Guangzhou University
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China
Control flowering time, an important determinant for soybean yield and adaptation.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
Guangzhou University
Yunnan Agricultural University
Nanjing Agricultural University
Key Laboratory of Crop Genetics and Breeding of Hebei, China
Altered plant architecture to increase yield: more compact plant architecture.
(Kong et al., 2023)
SDN1
CRISPR/Cas
Nanjing Agricultural University
Chinese Academy of Agricultural Sciences
Hebei Academy of Agricultural and Forestry Sciences, China
Shorter flowering time and increased yield.
( Cheng et al., 2023 )
SDN1
CRISPR/Cas
Jilin Normal University
Jilin Academy of Agricultural Sciences, China
Shortened flowering time and maturity, determining their favourable latitudinal zone for cultivation.
( Gao et al., 2024 )
SDN1
CRISPR/Cas
Syngenta Seed Technology China Co., China
Bigger seeds and increased yield.
( Xie et al., 2024 )
SDN1
CRISPR/Cas
Anhui Agricultural University
Anhui Agricultural University
Bellagen Biotechnology Co. Ltd
Ministry of Agriculture and Rural Affairs
Southern University of Science and Technology
Hainan Yazhou Bay Seed Laboratory, China
Dwarf phenotype, which can aid in obtaining more compact, densely planted soybean varieties to boost productivity.
( Xiang et al., 2024 )
SDN1
CRISPR/Cas
Wuhan Polytechnic University
Chinese Academy of Agricultural Sciences, China
Increased seed size and yields without alterations in plant architecture or seed nutrition.
( Wang et al., 2024 )
SDN1
CRISPR/Cas
Northeast Forestry University
Northeast Agricultural University, China
Earlier maturation time under both short-day and long-day conditions.
( Wu et al., 2024 )
SDN1
CRISPR/Cas
Heilongjiang Bayi Agricultural University
Chinese Academy of Agricultural Sciences
Northeast Agricultural University
Syngenta Biotechnology (China) Co. Ltd, China
Increased grain yield.
( Chen et al., 2024 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Chinese Academy of Agricultural Sciences
Tianjin Academy of Agricultural Sciences
Chinese Academy of Agricultural Sciences
Minzu University of China
Hebei Academy of Agriculture and Forestry Science, China