Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Displaying 55 results

Traits related to industrial utilization

Early heading: in regions with short growing seasons, early maturing varieties to escape frost damage are required.
(Sohail et al., 2022)
SDN1
CRISPR/Cas
China National Rice Research Institute
Northern Center of China National Rice Research Institute
Zhejiang A&
F University, China
Mir Chakar Khan Rind University
Agriculture Research System Khyber, Pakistan
Ministry of Agriculture, Bangladesh
Agriculture Research Center, Egypt
Early heading: timing of heading is crucial for the reproduction and the geographical expansion of cultivation of rice.
(Sun et al., 2022)
SDN1
CRISPR/Cas
China National Rice Research Institute
Shanghai Academy of Agricultural Sciences
Northern Center of China National Rice Research Institute
Xuzhou Institute of Agricultural Sciences, China
Enabled clonal reproduction trough seeds. Application of the method may enable self-propagation of a broad range of elite F1 hybrid crops.
( Wang et al., 2019 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Université Paris-Saclay, France
Late flowering time.
( Li et al., 2022 )
SDN1
CRISPR/Cas
Zhejiang University
China Zhejiang Zhengjingyuan Pharmacy Chain Co., Ltd. &
Hangzhou Zhengcaiyuan Pharmaceutical Co., China
Accelerated abscission. Plant organ abscission is a process important for development and reproductive success,
( Liu et al., 2022 )
SDN1
CRISPR/Cas
Shenyang Agricultural University
Key Laboratory of Protected Horticulture of Ministry of Education, China
University of California at Davis
Crops Pathology and Genetic Research Unit, USA
35% reduction in lignin. Fourfold increase in cellulose-to-glucose conversion upon limited saccharification. Efficient saccharification is hindered by the presence of lignin in the secondary-thickened cell walls.
( de Vries et al., 2021 )
SDN1
CRISPR/Cas
Ghent University
VIB Center for Plant Systems Biology, Belgium
Reduced lignin content and increased sugar release upon saccharification.
( De Meester et al., 2021 )
SDN1
CRISPR/Cas
Ghent University
VIB Center for Plant Systems Biology, Belgium
Male sterility: mutants did not produce pollen and induced a parthenocarpic fruit set.
(Gökdemir et al., 2022)
SDN1
CRISPR/Cas
Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University, Turkey
Improved saccharification efficiency by an altered cell wall architecture.
( Nayeri et al., 2022 )
SDN1
CRISPR/Cas
Shahid Beheshti University
University of Tabriz, Iran
Enhanced biological nitrogen fixation to reduce the use of inorganic nitrogen fertilizers. Enhanced biofilm formation of soil diazotrophic bacteria by modified root microbiome structure.
( Yan et al., 2022 )
SDN1
CRISPR/Cas
University of California
Bayer Crop Science, USA
Enhanced genetic recombination frequency to increase genetic diversity and disrupting genetic interference.
( Liu et al., 2021 )
SDN1
CRISPR/Cas
China National Rice Research Institute
Chinese Academy of Sciences
Chinese Academy of Agricultural Sciences, China
Thermosensitive genic male sterile lines with high blast resistance and fragrance quality. Resources for hybrid rice breeding.
( Liang et al., 2022 )
SDN1
CRISPR/Cas
China National Rice Research Institute, China
Parthenocarpy: seedless tomatoes
(Nieves-Cordones et al., 2020)
SDN1
CRISPR/Cas
Centro de Edafología y Biología Aplicada del Segura-CSIC, Spain
Tailoring poplar lignin without yield penalty. Reduced recalcitrance.
( De Meester et al., 2020 )
SDN1
CRISPR/Cas
Ghent University
VIB Center for Plant Systems Biology
VIB Metabolomics Core, Belgium
Regulation of flowering time and drought tolerance: flowered 9.6 and 5.8 days earlier.
(Gu et al., 2022)
SDN1
CRISPR/Cas
Yangzhou University, China
Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Bao et al., 2022 )
SDN1
CRISPR/Cas
Yunnan Agricultural University
Yunnan Academy of Agriculture Sciences, China
Generating male sterility lines (MLS) and enhanced tolerance against drought stress. Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Secgin et al., 2022 )
SDN1
CRISPR/Cas
Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University
Ondokuz Mayıs University, Turkey
Agricultural Research Center (ARC), Egypt
Wine fermentation: minimize ethyl carbamate (EC) accumulation. EC is a potential carcinogen to humans. EC is mainly produced through the reaction between urea and ethanol during the Chinese wine brewing process.
(Wu et al., 2020)
SDN2
CRISPR/Cas
Jiangnan University
Zhejiang Shuren University, China
Generation of male sterility lines. Heterosis, the breeding result in which heterozygous hybrid progeny are superior to both homozygous parents, depends on the selection and application of male-sterile lines (MSL). Using MSL can reduce the production cost of hybrid seeds and improve its quality.
( Chen et al., 2021 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
University of Chinese Academy of Sciences
Jilin Agricultural University
Jilin Academy of Agricultural Sciences, China
Control photoperiodic flowering to allow adaptation of cultivars. Flowering time is a critical characteristic to determine the geographic distribution and regional adaptability of soybean.
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Generating male sterility lines (MSL). MS is the absence or non-function of pollen grain in plant or incapability of plants to produce or release functional pollen grains. Using MS lines eliminates the process of mechanical emasculation in hybrid seed production.
( Zou et al., 2017 )
SDN1
CRISPR/Cas
Sichuan Agricultural University, China
Jointless tomatoes. Pedicel abscission is an important agronomic factor that controls yield and post-harvest fruit quality. In tomato, floral stems that remain attached to harvested fruits during picking mechanically damage the fruits during transportation, decreasing the fruit quality for fresh-market tomatoes and the pulp quality for processing tomatoes.
( Roldan et al., 2017 )
SDN1
CRISPR/Cas
Institute of Plant Sciences Paris-Saclay (IPS2), France
University of Liège, Belgium
Rescued male fertility. Hybrids between divergent populations commonly show hybrid sterility; this reproductive barrier hinders hybrid breeding of the japonica and indica rice subspecies.
( Shen et al., 2017 )
SDN1
CRISPR/Cas
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources
Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions
South China Agricultural University, China
Early maturity of rice varieties. Rice is a tropical short-day plant. The northward cultivation in China is accompanied with daylength extension and temperature decrease, which are unfavorable for rice, to complete flowering and seed setting.
( Li et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
Jiangsu Academy of Agricultural Sciences, China
Restoring cytoplasmic sterility.
( Kazama et al., 2019 )
SDN2
TALENs
Tohoku University
Tamagawa University
The University of Tokyo
National Institute of Genetics
Tokyo Institute of Technology
Tamagawa University
Japan Science and Technology Agency, Japan
Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )
SDN1
CRISPR/Cas
University of California
Emory University, USA
University of Cambridge, UK
Male sterility for hybrid seed production reduces costs and ensures high varietal purity.
( Du et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
Beijing Academy of Agriculture and Forestry Sciences
Zhejiang Agricultural and Forestry University, China
Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Jung et al., 2020 )
SDN1
CRISPR/Cas
Hankyong National University
Hanyang University
Sunchon National University
Chungbuk National University
Tomato Research Center, South Korea
Increasing cross over frequency. Cross over formation during meiosis is essential for crop breeding to introduce favourable alleles controlling important traits from wild relatives into crops.
( de Maagd et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Liu et al., 2021 )
SDN1
CRISPR/Cas
Northwest A&
F University
Xi’an Jinpeng Seedlings Co. Ltd.
Hybrid Rapeseed Research Center of Shaanxi Province, China
Stem wood discoloration due to lignin reduction.
( Zhou et al., 2015 )
SDN1
CRISPR/Cas
University of Georgia, USA
Complete reproductive sterility to prevent the spread of highly domesticated, exotic or genetically modified organisms into wild populations.
( Azeez et al., 2021 )
SDN1
CRISPR/Cas
Michigan Technological University, USA
Confer male sterility for hybrid seed production. Male sterility is an important trait, especially for self-pollinated crops such as rice.
( Ma et al., 2019 )
SDN1
CRISPR/Cas
South China Agricultural University, China
Generation of a new thermo-sensitive genic male sterile rice line for hybrid breeding of indica rice.
( Barman et al., 2019 )
SDN1
CRISPR/Cas
China National Rice Research Institute, China
Bangladesh Rice Research Institute, Bangladesh
Fertility restoration of cytoplasmic male sterility.
( Suketomo et al., 2020 )
SDN1
CRISPR/Cas
Tohoku University, Japan
Male sterility and decreased total fatty acid content in the anther.
( Basnet et al., 2019 )
SDN1
CRISPR/Cas
Zhejiang University
Yangtze University, China
Domestication: Conferred domesticated phenotypes yet retained parental disease resistance (predominately Xanthomonas perforans), and salt tolerance.
(Li et al., 2018)
SDN1
CRISPR/Cas
University of Chinese Academy of Sciences, China
Development of commercial thermosensitive genic male sterile lines to accelerate hybrid rice breeding.
( Zhou et al., 2016 )
SDN1
CRISPR/Cas
State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources
Key Laboratory of Plant Functional Genomics and Biotechnology of Guangdong Provincial Higher Education Institutions
South China Agricultural University
China National Hybrid Rice R&
D Center, China
Induction of haploid plants and a reduced seed set for rice breeding.
( Yao et al., 2018 )
SDN2
CRISPR/Cas
ZhongGuanCun Life Science Park, China
Syngenta India Limited
Technology Centre
Medchal Mandal, India
Syngenta Crop Protection
LLC
Research Triangle Park, USA
Asexual propagation trough seeds. Induction of apomeiosis, mitosis instead of meiosis. This proces leads to the production of genetically identical seeds, serving many applications in plant breeding.
( Khanday et al., 2019 )
SDN1
CRISPR/Cas
University of California
Innovative Genomics Institute
Iowa State University, USA
Université Paris-Saclay, France
Genetic variability. The genetically reprogrammed rice plants can act as donor lines to stabilize important agronomic traits or can be a potential resource to create more segregating population.
( K et al., 2021 )
SDN1
CRISPR/Cas
University of Agricultural Sciences
Regional Centre for Biotechnology, India
Creation of photoperiod-/thermo-sensitive genic male-sterile (P/TGMS) lines, important for commercial rice breeding. P/TGMS rice lines are useful germplasm resources for two-line hybrid breeding.
( Lan et al., 2019 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Peking University Institute of Advanced Agricultural Sciences
School of Advanced Agriculture Sciences and School of Life Sciences
Peking University
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement,China
Removal of methyl iodide emissions. The release of methyl iodide in the athmospere causes ozone depletion and thus represents an important environmental threat.
( Carlessi et al., 2021 )
SDN1
CRISPR/Cas
PlantLab
Institute of Life Sciences
Scuola Superiore Sant’Anna
University of Pisa
University of Milan, Italy
Enhanced biomass saccharification by altered lignin biosynthesis. The intrinsic recalcitrance of lignocellulose residues requires high energy input for bioethanol production.
( Zhang et al., 2020 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Hubei University of Arts &
Science
Guangxi University, China
Prolonged basic vegetative growth periods for flexible cropping systems in southern China, as well as in other low-latitude regions. Most of the mid-latitude varities were sensitive to temperature or photoperiod, resulting in low grain yield when cultivated in low-latitude regions.
( Wu et al., 2020 )
SDN1
CRISPR/Cas
Fujian Agricultural and Forestry University
Fujian Academy of Agricultural Sciences
Minjiang University, China
Production of herbicide-sensitive strain to prevent volunteer infestation. Volunteer rice grows when cultivated rice seed fall into fields, overwinter and spontaneously germinate the next spring.
( Komatsu et al., 2020 )

BE
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Graduate School of Science
Technology and Innovation, Japan
Rescued hybrid female fertility. Hybrids between divergent populations commonly show hybrid sterility; this reproductive barrier hinders hybrid breeding of the japonica and indica rice subspecies.
( Guo et al., 2023 )
SDN1
CRISPR/Cas
Ministry of Agriculture and Rural Affairs
Guangdong Key Laboratory of New Technology in Rice Breeding
Guangdong Academy of Agricultural Sciences
South China Agricultural University, China
Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high seed purity during hybrid seed production.
( Zhou et al., 2023 )
SDN1
CRISPR/Cas
Beijing Academy of Agriculture and Forestry Sciences
Chinese Academy of Sciences
China Agricultural University, China
Enhanced biomass saccharification by remodelling of cell wall composition.
( Dang et al., 2023 )
SDN1
CRISPR/Cas
Shenyang Agricultural University/Key Laboratory of Northern geng Super Rice Breeding, China
Modified wood composition with traits desirable for fiber pulping and lower carbon emissions. The edited wood could bring efficiencies, bioeconomic opportunities and environmental benefits.
( Sulis et al., 2023 )
SDN1
CRISPR/Cas
North Carolina State University
University of Illinois at Urbana-Champaign, USA
Beihua University
Northeast Forestry University, China
Higher haploid induction rate. Haploid induction allows formation of doubled haploids, which can be used to rapidly fix genetic information.
( Jang et al., 2023 )
SDN1
CRISPR/Cas
Chonnam National University
Pusan National University
Kyung Hee University, South Korea
Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas. Complete abolition of pollen development.
( An et al., 2023 )
SDN1
CRISPR/Cas
University of Science and Technology Beijing
Yili Normal University
Zhongzhi International Institute of Agricultural Biosciences
Beijing Solidwill Sci-Tech Co. Ltd., China
Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Wu et al., 2024 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
University of Chinese Academy of Sciences
Jilin Agricultural University
Zhejiang Lab, China
Dwarf plants that retain favourable fruit traits.
( Nagamine et al., 2024 )
SDN1
CRISPR/Cas
University of Tsukuba, Japan