genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 34 results

Traits related to biotic stress tolerance

Broad-spectrum disease resistance without yield loss.
( Sha et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Chengdu Normal University
Jiangxi Academy of Agricultural Sciences
Anhui Agricultural University
BGI-Shenzhen
Northwest A&
F University
Shandong Academy of Agricultural Sciences, China
Université de Bordeaux, France
University of California
The Joint BioEnergy Institute, USA
University of Adelaide, Australia

Viral resistance: improved resistance to yellow leaf curl virus (TYLCV).
(Tashkandi et al., 2018)

SDN1
CRISPR/Cas

Princess Nourah bint Abdulrahman University
4700 King Abdullah University of Science and Technology, Saudi Arabia

Detection method for the geminiviruses, tomato yellow leaf curl virus and tomato leaf curl New Delhi virus, which can cause huge economic losses and pose a threat to sustainable agriculture.
( Mahas et al., 2021 )

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology (KAUST), Saudi Arabia

Viral resistance: resistance to Tomato yellow leaf curl virus (TYLCV). Delayed or reduced accumulation of viral DNA and abolished or attenuated symptoms of infection.
(Ali et al., 2015)

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia

Viral resistance: partial resistance to Pepper veinal mottle virus (PVMV) isolate IC, with plants harboring weak symptoms and low virus loads at the systemic level.
(Moury et al., 2020)

SDN1
CRISPR/Cas

INRA, France
Université de Tunis El-Manar
Université de Carthage, Tunisia
Université Felix Houphouët-Boigny, Cote d’Ivoire
Institut de l’Environnement et de Recherches Agricoles, Burkina Faso

Traits related to abiotic stress tolerance

Improved salt stress resistance. Significant increase in the shoot weight, the total chlorophyll content, and the chlorophyll fluorescence under salt stress. Also high antioxidant activities coincided with less reactive oxygen species (ROS).
( Shah Alam et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University, China
Taif University, Saudi Arabia
Alexandria University, Egypt

Drought and salt tolerance.
( Curtin et al., 2018 )

SDN1
CRISPR/Cas

University of Minnesota, USA
The University of Newcastle, Australia

Traits related to improved food/feed quality

Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)

SDN1
CRISPR/Cas

Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia

Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )

SDN1
CRISPR/Cas

Zhejiang University, China
La Trobe University, Australia

Increased amylose content in the seeds, thus a lower Glycemic Index (GI) value. Low GI rice is preferred to avoid a sudden rise in glucose in the bloodstream. Starch with a high GI threatens healthy individuals to get diabetes type II and proves extremely harmful for existing diabetes type II patients.
( Jameel et al., 2022 )

SDN1
CRISPR/Cas

Jamia Millia Islamia
International Centre for Genetic Engineering and Biotechnology, India
King Saud University, Saudi Arabia

Reduced browning and acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods and is regarded as a potential carcinogen and neurotoxin.
( Nguyen Phuoc Ly et al., 2023 )

SDN1
CRISPR/Cas

Murdoch University, Australia

Reduce or eliminate amylose content in root starch. Amylose influences the physicochemical properties of starch during cooking and processing.
( Bull et al., 2018 )

SDN1
CRISPR/Cas

Institute of Molecular Plant Biology, Switzerland

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia

Reduced levels of very long chain saturated fatty acids in kernels, which are associated with revalance of atherosclerosis and cardiovascular disease.
( Huai et al., 2024 )

SDN1
CRISPR/Cas

Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, China
International Crops Research Institute of the Semi-Arid Tropics (ICRISAT), India
Murdoch University, Australia

Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia

Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia

Specific differences in grain morphology, composition and (1,3;1,4)-β-glucan content. Barley rich in (1,3;1,4)-β-glucan, a source of fermentable dietary fibre, is useful to protect against various human health conditions. However, low grain (1,3;1,4)-β-glucan content is preferred for brewing and distilling.
( Garcia-Gimenez et al., 2020 )

SDN1
CRISPR/Cas

The James Hutton Institute
University of Dundee, UK
University of Adelaide
La Trobe University, Australia

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia

Traits related to increased plant yield and growth

Plant architecture: high tillering and reduced height.
(Butt et al., 2018)

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia

Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )

SDN1
CRISPR/Cas

Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China

Increase in plant height, tiller number, grain protein content and yield. 1.5- to 2.8-fold increase in total chlorophyll content in the flag leaf at the grain filling stage. Delayed senescence by 10–14 days. High nitrogen content in shoots under low nitrogen conditions.
( Karunarathne et al., 2022 )

SDN1
CRISPR/Cas

Murdoch University
Department of Primary Industries and Regional Development, Australia

Various phenotypic changes were observed of which traits such as plant dwarfing, color, shape, and weight, early flowering, a high number of flowers and early fruit set and maturation, fewer seeds, and reduced and delayed browning of fruits are agronomically important.
( Kodackattumannil et al., 2023 )

SDN1
CRISPR/Cas

United Arab Emirates University, United Arab Emirates

Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, Australia

Increased grain yield and quality.
( Luo et al., 2024 )

SDN1
CRISPR/Cas

Guizhou University, China
King Saud University, Saudi Arabia

Traits related to industrial utilization

Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )

SDN1
CRISPR/Cas

The University of Adelaide, Australia
Huaiyin Normal University, China

Accelerate flowering, a rare event under glasshouse conditions. Modified starch.
( Bull et al., 2018 )

SDN3
CRISPR/Cas

Institute of Molecular Plant Biology, Switzerland

Traits related to herbicide tolerance

Imazethapyr, imazapic
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu University, China
CSIRO Agriculture and Food, Australia

Herboxidiene
( Butt et al., 2019 )

SDN1
CRISPR/Cas

King Abdullah University of Science and Technology (KAUST), Saudi Arabia
Universite Paris-Saclay, France

Herbicide tolerance (ALS-targeting)
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu Academy of Agricultural Sciences
Jiangsu University, China
CSIRO Agriculture and Food, Australia

Bispyribac sodium
( Butt et al., 2017 )

SDN2
CRISPR/Cas

King Abdullah University of Science and Technology, Saudi Arabia
Agricultural Research Center, Egypt
Rice University, USA

Herbicide glyphosate tolerance.
( Arndell et al., 2019 )

SDN1
CRISPR/Cas

CSIRO
New South Wales Department of Primary Industries
The University of Adelaide, Australia

Bispyribac sodium
( Butt et al., 2020 )

King Abdullah University of Science and Technology (KAUST), Saudi Arabia

Traits related to product color/flavour

Albinism and dwarfing.
( Naim et al., 2018 )

SDN1
CRISPR/Cas

Queensland University of Technology, Australia

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour